Browse publications by year: 2012

  1. Ng SC, Tsoi KK, Kamm MA, Xia B, Wu J, Chan FK, et al.
    Inflamm. Bowel Dis., 2012 Jun;18(6):1164-76.
    PMID: 21887729 DOI: 10.1002/ibd.21845
    BACKGROUND: Inflammatory bowel diseases (IBD) result from an interaction between genetic and environmental factors. Preliminary findings suggest that susceptibility genes differ between IBD patients in Asia and the West. We aimed to evaluate disease-predisposing genes in Asian IBD patients.

    METHODS: A systematic review and meta-analysis were performed of published studies from 1950 to 2010 using keyword searches in MEDLINE, EMBASE, EBM Reviews, and BIOSIS Previews.

    RESULTS: In all, 477 abstracts were identified and data extracted from 93 studies, comprising 17,976 IBD patients and 27,350 age- and sex-matched controls. Major nucleotide oligomerization domain (NOD)-2 variants in Western Crohn's disease (CD) patients were not associated with CD in Han Chinese, Japanese, South Korean, Indian, and Malaysian populations. New NOD2 mutations were, however, associated with CD in Malaysians (JW1), Han Chinese, and Indians (P268S). Autophagy-related protein 16-linked 1 (ATG16L1) was not associated with CD in East Asians (odds ratio [OR] 0.97; 95% confidence interval [CI] 0.84-1.13). Interleukin (IL)-23R was associated with CD in South Koreans (OR 1.8; 95% CI 1.16-2.82) and a single nucleotide polymorphism in IL-23R (Gly149Arg) was protective of CD in Han Chinese (OR 0.3; 95% CI 0.15-0.60). Tumor necrosis factor (TNF) superfamily gene-15 (SF15) polymorphisms were associated with CD (OR 2.68; 95% CI 1.86-3.86), while TNF-308 polymorphisms (OR 1.82; 95% CI 1.15-2.9), cytotoxic T lymphocyte antigen (CTLA)-4 (OR 2.75; 95% CI 1.22-6.22) and MICA allele (OR 2.41; 95% CI 1.89-3.07) were associated with ulcerative colitis in Asians.

    CONCLUSIONS: Genetic mutations of IBD in Asians differ from Caucasians. New mutations and susceptibility genes identified in Asian IBD patients provide an opportunity to explore new disease-associated mechanisms in this population of rising incidence.

    MeSH terms: Humans; Meta-Analysis as Topic; Inflammatory Bowel Diseases/genetics*; Genetic Predisposition to Disease*; Asian Continental Ancestry Group/genetics*
  2. Katsuura Y, Russell V
    Ir J Psychol Med, 2012 Jan;29(3):171-175.
    PMID: 30200052 DOI: 10.1017/S0790966700017201
    We report on the case of a middle-aged woman with a complex psychiatric history in whom atypical intrusive imagery identified in the mental status examination appeared to represent an emergence of childhood dissociative phenomena. These new symptoms led to the reappraisal of her clinical presentation and a diagnostic re-evaluation that they represented a re-emergence of childhood post-traumatic stress disorder secondary to sexual abuse. We discuss the phenomenology identified in our patient with the aim of increasing awareness of unusual symptoms in adults with a history of childhood sexual abuse and the importance of the mental state examination in eliciting and classifying such phenomena.
    MeSH terms: Adult; Dissociative Disorders; Female; Humans; Middle Aged; Sex Offenses; Stress Disorders, Post-Traumatic; Imagery (Psychotherapy)
  3. Mohamad N, Ponnusamy S, Devi S, Manikam R, Idrus II, Bakar NHA
    Res Rep Trop Med, 2012;3:103-106.
    PMID: 30100777 DOI: 10.2147/RRTM.S34483
    Melioidosis presents with a wide range of clinical presentations, which include severe community-acquired pneumonia, septicemia, central nervous system infection, and less severe soft tissue infection. Hence, its diagnosis depends heavily on the clinical microbiology laboratory for culture. In this case report, we describe an atypical presentation of melioidosis in a 52-year-old man who had fever, right upper-abdominal pain, and jaundice for 15 days. Melioidosis caused by Burkholderia pseudomallei was subsequently diagnosed from blood culture. As a primary care physician, high suspicion index is of great importance. High suspicion index of melioidosis in a high-risk group patient, such as the patient with diabetes mellitus and diabetic foot, is crucial in view of atypical presentations of pseudomonas sepsis. A correct combination of antibiotic administration in the early phase of therapy will determine its successful outcome.
    MeSH terms: Anti-Bacterial Agents; Central Nervous System Infections; Fever; Humans; Jaundice; Male; Melioidosis; Middle Aged; Pneumonia; Pseudomonas; Pseudomonas Infections; Abdominal Pain; Bacteremia; Burkholderia pseudomallei; Diabetic Foot; Soft Tissue Infections; Sepsis; Physicians, Primary Care; Blood Culture
  4. Jaffry Zakaria
    MyJurnal
    The racial riot incident on 13th of May 1969 had opened the eyes of many people to realize on how important serious efforts to be focused in managing the sensitivity and the differences in multiracial society in countries like Malaysia. Many experts believe that integration can be build through outdoor education activities. The author will try to unravel and discuss on the outdoor education activity relations and integration campus community. This discussion will cover the latest issues and a variety of previous studies and personal experiences of the author as an outdoor education activist.
    MeSH terms: Eye; Humans; Malaysia; Riots; Societies; Continental Population Groups; Community Integration
  5. Yusop Ahmad, Nur Haziyanti Mohamad Khalid, Trevor Glen Philip
    MyJurnal
    This study aimed to test the effect of modality imagery training via video tapes and audio tapes to improve the performance of overhead service skills in volleyball. 45 subjects who followed the volleyball professional course in Sultan Idris University of Education (UPSI) were selected for this test and they were randomly divided into three groups: video, audio group and control group. Russel-Lange Volleyball Test was used to obtain data on the overhead service performance. The results showed significant differences in overhead service performance before and after participants were exposed to the methods of video and audio tapes. There were also significant differences in overhead service performance among the video, audio, and control group. The study should that the introduction of audio and video imagery method may helps improve the overhead service skills performance in volley ball.
    MeSH terms: Communications Media; Eugenol; Humans; Zinc Oxide; Control Groups; Volleyball
  6. Nathan, Sanmuga
    MyJurnal
    This quasi-experimental study examined the effectiveness of SET pedagogical style training that combined teaching style E (Inclusion style) from Mosston Spectrum of Teaching Styles (Mosston & Ashworth, 2002) with Teaching Games for Understanding (TGfU), in hockey. A total of n=25, Form One low-skilled students (LSS) secondary school boys were involved in this study using Physical Education class for the duration of nine weeks. The effectiveness of the SET pedagogical style of training on LSS in hockey was measured using speed and accuracy executing general hockey skills, acquisition of declarative and procedural hockey knowledge as well as ball control, decision making (passing, tackling, dribbling and scoring) and skill execution (passing, tackling, dribbling and scoring) in 3 vs 3 game play. The data was analysed using MANCOVA together with other two training styles, which was not disclosed in this article. Findings indicated there were significant improvements in speed and accuracy executing hockey general skills, declarative and procedural knowledge using SET pedagogical style of training. Findings too revealed the SET style was able to develop significantly game components of ball control, decision makng and skill execution in 3 vs 3 game plays at posttest among LSS group. Conclusion, further research has to be done to validate the SET pedagogical style of training across many invasion games.
    MeSH terms: Decision Making; Hockey; Humans; Learning; Male; Physical Education and Training; Research; Students; Knowledge
  7. Nur Haziyanti Mohamad Khalid
    MyJurnal
    A study was conducted to examine resilience profiles among Sport Science students (N=280) in Sultan Idris Education University, Tanjong Malim. The resilience aspects were comprising risk factors, protective factors such as resilience strength, emotional intelligence, and locus of control, and also resilience outcomes in terms of students’ mental health status and their academic achievement. Adult Resiliency Attitudes Scale (ARAS), BarOn Emotional Quotient Inventory: Youth Version (BarOn EQi:YV), Rotter’s Locus of Control Scale, Depression, Anxiety and Stress Scale (DASS) and students final examination results were used to measure the profiles. The results indicate that the academic factor was among the highest risk factors which contribute stress to the students. In terms of protective factors, students were strong enough in their morality aspect (resiliency strength), general mood (emotional intelligence) and internal locus of control. In fact, Sport Science students should possess very significant protective factors in terms of their resiliency strength, emotional intelligence and internal locus of control in order to face any future risk factors and to stabilize their mental health status.
  8. Nelfianty Mohd Rasyid, Shaharudin Abd Aziz
    MyJurnal
    The purpose of this study was to identify the preferred coaching styles of the Malaysian Sports School athletes based on gender, age group, and types of sports they had participated. This study utilised the athletes preferred version of the Leadership Scale for Sport questionnaire (LSS). The subjects were the population of two Malaysian Sport School athletes (N = 854; Bukit Jalil Sports School = 409, Bandar Penawar Sports School = 445). The findings demonstrated that Training and Instruction (M = 4:09, SD = 73) was the most preferred leadership style by the athletes, followed by Democratic (M = 3.87, SD = .75), Social Support (M = 3.74, SD = .75) and Positive Feedback (M = 3:59, SD = .82). Autocratic behavior was the least preferred coaching style (M = 2.35, SD = 96). T-test analysis showed that there were significant differences between autocratic leadership style t(852) = 4.63, p
    MeSH terms: Leadership; Surveys and Questionnaires; Social Support; Sports; Athletes; Educational Personnel; Mentoring
  9. Kuan Boon, Ong, Timothy R Ackland
    MyJurnal
    Athletes and coaches in the sport of sprint kayaking and canoeing face contradicting philosophies about the optimum physical structure of the paddler and equipment setup characteristics. There exists however, little normative data in the scientific literature for the current physical size and proportionality characteristics as well as equipment set-up of World-class or Asian sprint paddlers. These data and basic understanding of paddlers’ morphology and boat set-up would be useful for Malaysian coaches when initially selecting talented individuals for development programs as well as in determining their specialist events. Ackland et al. (2003) found that participants in Olympic sprint paddling events considered to be homogeneous in shape and physical size, male and female paddlers have SAMs of 1.1 and 1.0 respectively. Compared to other athlete groups the variance in stature and body mass of paddlers is generally low. Whilst sprint paddlers are not athletes with extreme proportionality profiles, they do possess unique characteristics not commonly observed in the general population. Whereas in equipment set-up, Ong et al. (2005) found that there are consistent differences for both male and female athletes among sprint and slalom kayak paddlers who competed at the 2000 Olympic Games in Sydney. The sprint paddlers seated higher and using longer paddles with longer, though narrower blades (p>0.0001). But, among male sprint paddlers, only minor differences in equipment set-up were found between competitors ranked in the top 10 places to the rest of the field. Significant (p
  10. Mohar Kassim
    MyJurnal
    This research is to study the knowledge of four (n=4) coaches in training at two football academies in Malaysia. This study applied a qualitative methodology (interviews and observations) to explore the unique features and circumstances surrounding the football academy coaches. Subsequently, the findings of this study revealed that i) the development of knowledge of coaching has taken place in the academy but constrained by factors involving the coach education programme at the academy level; ii) the weaknesses of the coaches in transferring important knowledge to the players.
    MeSH terms: Academies and Institutes; Football; Malaysia; Research; Soccer; Knowledge; Mentoring
  11. Lee Ai Choo, Magee, David, Choptain, Tracy, Dhillon, Sat
    MyJurnal
    The objective of this systematic review was to assess the effectiveness of physical therapy interventions for chronic soft tissue injury to the low back. Only randomized controlled trials identifying physical therapy interventions within the scope of practice for Canadian physiotherapists and athletic therapists, with a clinical diagnosis of chronic soft tissue injury to the low back with symptoms lasting a minimum of three months were included. Only three studies of the 87 articles reviewed were deemed eligible for review based on the relevancy criteria set forth by the reviewers. Percutaneous electrical nerve stimulation (PENS) and therapist supervised active exercise programs may be a promising treatment modality for chronic low back pain (CLBP) by reducing pain, improving self-reported disability, and improving physical performance. The consensus amongst reviewers’ was that the quality of the three articles were deemed of weak methodological quality making author inferences to the success of the reported physical interventions towards the modulation of pain, improved range of motion or patient satisfaction inconclusive. At the most basic level, there is a lack of uniformity in defining low back pain based on time, with definitions ranging anywhere from one week to six months. This is a major limitation in existing scientific literature. The ability to compare studies and results is hampered by the disparities in CLBP definition. The scientific rigor applied to studies devoted to therapeutic interventions and rehabilitation is poor.
  12. Julismah Jani, Syed Kamaruzaman Syed Ali
    MyJurnal
    The objectives of this study were to determine level of acquisition, implementation and differences of pedagogical content knowledge among physical education teachers It also examined the relationship between pedagogical content knowledge and its implementation during physical education lesson. About 149 of Form 4 physical education teachers in Ulu Kinta, Perak, Malaysia secondary schools and 125 physical education teachers of X class in upper secondary schools of Surabaya, Indonesia were involved in this study. Data of the study was collected through questionnaires The findings delineate a medium level (M = 2.90) of pedagogical content knowledge of Malaysian physical education teachers and 86.3% have implemented in their lessons. Whilst the Indonesian physical education teachers acquired a high level of pedagogical content knowledge (M = 3.69) and 94.2% have implemented during their physical education lessons. There was a significant (p = .00) difference among Malaysian and Indonesian physical education teachers on acquisition of pedagogical content knowledge. The findings also delineate a medium positive and significant relationship between pedagogical content knowledge and its implementation during physical education lesson of Malaysian (r = .622, p < .01) and Indonesian (r = .647, p < .01) physical education teachers respectively. The results of the study implied that pedagogical content knowledge is a specific domain to teaching process. Teachers are able to develop their current dimension and goals or contemporary of pedagogical content knowledge based on current needs and their own ability and contentment. Therefore, teachers should acquire pedagogical content knowledge so that their teaching would be meaningful and effective for students learning.
    MeSH terms: Goals; Indonesia; Learning; Malaysia; Physical Education and Training; Surveys and Questionnaires; Schools; Students; Knowledge
  13. Taha NA, Ibrahim MI, Rahman AF, Shafie AA, Rahman AH
    Value Health Reg Issues, 2012 May;1(1):82-86.
    PMID: 29702832 DOI: 10.1016/j.vhri.2012.03.006
    OBJECTIVES: To explore the validity and reliability of a disease-specific health-related quality-of-life questionnaire-the Schizophrenia Quality of Life Scale Revision 4 (SQLS-R4)-in patients with schizophrenia in Malaysia.

    METHODS: A total of 222 outpatients with schizophrenia receiving treatment at the Universiti Kebangsaan Malaysia Medical Centre completed the SQLS-R4 in either the Malay or the English language. A generic self-report health-related quality-of-life measure-the EuroQoL group EuroQol five-dimensional questionnaire-and a measure of symptom severity-the Clinical Global Impression-Schizophrenia scale-were also administered to assess validity.

    RESULTS: Good internal consistency reliability was found for both the psychosocial and vitality domains (Cronbach's α = 0.95 and 0.85, respectively). Most items were also significantly correlated with their own scale score (rs ranging from 0.29 to 0.74). There was a moderate correlation between the SQLS-R4 "vitality" domain and the EuroQol five-dimensional questionnaire "usual activities" domain (rs = 0.44) and a large correlation between the SQLS-R4 "psychosocial" domain and the EuroQol five-dimensional questionnaire "anxiety/depression" domain (rs = 0.44-0.57). Most of the symptom dimensions of the Clinical Global Impression-Schizophrenia scale were also moderately correlated with the SQLS-R4 subscale scores.

    CONCLUSIONS: The SQLS-R4 is a valid and reliable health-related quality-of-life instrument for use in minimally ill patients with schizophrenia in Malaysia, but some of the items may be redundant and irrelevant. Validation of SQLS-R4 in different types of patients and various levels of illness severity is required to further verify its application.

  14. Craig AG, Khairul MF, Patil PR
    Malays J Med Sci, 2012 Apr;19(2):5-18.
    PMID: 22973133
    Malaria is a disease that causes enormous human morbidity and mortality. One feature of mature Plasmodium falciparum-infected erythrocytes leading to the development of severe malaria is thought to be cytoadherence and blockage of the microvasculature. Therefore, an understanding of mechanisms that mediate parasite adhesion leading to malaria pathology is needed to yield new treatments for malaria. However, to date, cytoadherence-associated pathology is still under debate. Is cytoadherence needed to develop severe malaria? This review will discuss the available information on associations of cytoadherence with the development of severe malaria.
  15. Han YZ, Ren TJ, Jiang ZQ, Jiang BQ, Gao J, Koshio S, et al.
    Fish Physiol. Biochem., 2012 Dec;38(6):1785-1794.
    PMID: 22763698 DOI: 10.1007/s10695-012-9675-4
    A 60-day feeding trial was conducted to determine the effects of palm oil blended with oxidized and non-oxidized fish oil on growth performances, hematology, and non-specific immune response in juvenile Japanese sea bass, Lateolabrax japonicas. Japanese sea bass (1.73 ± 0.01 g) were fed seven experimental diets containing 100 g/kg of dietary lipid in forms of palm oil (10P), fish oil (10F), fish oil blended with palm oil at different ratios, 6:4 (6F4P) and 4:6 (4F6P), oxidized fish oil (10OF), and oxidized fish oil blended with palm oil at different ratios, 6:4 (6OF4P) and 4:6 (4OF6P). After the feeding trial, the following results were illustrated. No significant effects were observed in survival, feed conversion ratio, condition factor, and hematocrit after feeding with experimental diets for 60 days. The relatively higher specific growth rate and hematology were observed in 6F4P. Furthermore, both palm oil and oxidized fish oil acted as a negatively on serum lysozyme activity (P < 0.05). This study suggested that a ration of 6F4P is recommended as an innocuous ratio for Japanese sea bass. Furthermore, according to the present investigation, palm oil seems to have the ability to improve the protein efficiency when added to oxidized fish diets as well as a positive trend to the growth performance (P > 0.05).
    MeSH terms: Animals; Animal Feed/analysis; Animal Nutritional Physiological Phenomena; Diet/veterinary; Fish Oils/pharmacology*; Fish Oils/chemistry; Oxidation-Reduction; Perciformes/blood*; Perciformes/growth & development*; Perciformes/immunology; Plant Oils/pharmacology*; Plant Oils/chemistry; Dietary Supplements
  16. Praveena SM, Kwan OW, Aris AZ
    Environ Monit Assess, 2012 Nov;184(11):6855-68.
    PMID: 22146822 DOI: 10.1007/s10661-011-2463-2
    Principal component analysis (PCA) is capable of handling large sets of data. However, lack of consistent method in data pre-treatment and its importance are the limitations in PCA applications. This study examined pre-treatments methods (log (x + 1) transformation, outlier removal, and granulometric and geochemical normalization) on dataset of Mengkabong Lagoon, Sabah, mangrove surface sediment at high and low tides. The study revealed that geochemical normalization using Al with outliers removal resulted in a better classification of the mangrove surface sediment than that outliers removal, granulometric normalization using clay and log (x + 1) transformation. PCA output using geochemical normalization with outliers removal demonstrated associations between environmental variables and tides of mangrove surface sediment, Mengkabong Lagoon, Sabah. The PCA outputs at high and low tides also provided to better interpret information about the sediment and its controlling factors in the intertidal zone. The study showed data pre-treatment method to be a useful procedure to standardize the datasets and reducing the influence of outliers.
    MeSH terms: Environmental Monitoring/methods*; Malaysia; Water Pollutants, Chemical/analysis; Water Pollution, Chemical; Geologic Sediments/chemistry*; Principal Component Analysis/methods*
  17. Chan W, Mccrae RR, De Fruyt F, Jussim L, Löckenhoff CE, De Bolle M, et al.
    J Pers Soc Psychol, 2012 Dec;103(6):1050-1066.
    PMID: 23088227 DOI: 10.1037/a0029712
    Age trajectories for personality traits are known to be similar across cultures. To address whether stereotypes of age groups reflect these age-related changes in personality, we asked participants in 26 countries (N = 3,323) to rate typical adolescents, adults, and old persons in their own country. Raters across nations tended to share similar beliefs about different age groups; adolescents were seen as impulsive, rebellious, undisciplined, preferring excitement and novelty, whereas old people were consistently considered lower on impulsivity, activity, antagonism, and Openness. These consensual age group stereotypes correlated strongly with published age differences on the five major dimensions of personality and most of 30 specific traits, using as criteria of accuracy both self-reports and observer ratings, different survey methodologies, and data from up to 50 nations. However, personal stereotypes were considerably less accurate, and consensual stereotypes tended to exaggerate differences across age groups.
    MeSH terms: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Cross-Cultural Comparison*; Female; Humans; Male; Middle Aged; Personality/physiology*; Personality Inventory; Surveys and Questionnaires; Social Perception; Stereotyping*; Reproducibility of Results; Young Adult
  18. Ulrich S, Hesse M, Bröderbauer D, Wong SY, Boyce PC
    Taxon, 2012 Apr 13;61(2):281-292.
    PMID: 28904408
    Pollen characters in Araceae accord well with recent DNA-based phylogenies, and here we provide a new example of "compass needle" quality in Araceae on the basis of two closely related genera, Schismatoglottis and Apoballis. All investigated Schismatoglottis pollen is psilate (smooth pollen surface) with calcium crystals covering the pollen surface. By contrast, pollen of species transferred to recently resurrected Apoballis (Apoballis acuminatissima and A. mutata) is distinctively echinate (spiny). A unique layer covers the endexine of Schismatoglottis, and the whole pollen surface of Apoballis. Our findings strongly suggest that "Schismatoglottis" species with echinate pollen fall into the genus Apoballis. Moreover, all schismatoglottid taxa perform spathe movements during anthesis to control the movement of pollinators. The spathe movements of Apoballis acuminatissima clearly differ from those known in Schismatoglottis species, and indeed are so far unique for the entire family. This, together with differences in floral odour is strongly suggestive of differences in pollination ecology between the genera Schismatoglottis and Apoballis.
  19. Vithana EN, Khor CC, Qiao C, Nongpiur ME, George R, Chen LJ, et al.
    Nat. Genet., 2012 Oct;44(10):1142-1146.
    PMID: 22922875 DOI: 10.1038/ng.2390
    Primary angle closure glaucoma (PACG) is a major cause of blindness worldwide. We conducted a genome-wide association study including 1,854 PACG cases and 9,608 controls across 5 sample collections in Asia. Replication experiments were conducted in 1,917 PACG cases and 8,943 controls collected from a further 6 sample collections. We report significant associations at three new loci: rs11024102 in PLEKHA7 (per-allele odds ratio (OR)=1.22; P=5.33×10(-12)), rs3753841 in COL11A1 (per-allele OR=1.20; P=9.22×10(-10)) and rs1015213 located between PCMTD1 and ST18 on chromosome 8q (per-allele OR=1.50; P=3.29×10(-9)). Our findings, accumulated across these independent worldwide collections, suggest possible mechanisms explaining the pathogenesis of PACG.
    MeSH terms: Carrier Proteins/genetics*; Humans; Repressor Proteins/genetics; Glaucoma, Angle-Closure/genetics*; Logistic Models; Case-Control Studies; Genetic Predisposition to Disease*; Polymorphism, Single Nucleotide; Collagen Type XI/genetics*; Principal Component Analysis; Protein D-Aspartate-L-Isoaspartate Methyltransferase/genetics*; Genome-Wide Association Study*; Genetic Loci
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