Browse publications by year: 2016

  1. Nurazwa Ishak, Ahmad Firdaus Lajis, Rosfarizan Mohamad, Arbakariya Ariff, Murni Halim, Helmi Wasoh
    MyJurnal
    In this paper, the syntheses of kojic acid esters via chemical and enzymatic methods are
    reviewed. The advantages and disadvantages of chemical process in term of process, safety and
    efficiency are discussed. In enzymatic process, the significant process parameters related to the
    synthesis of kojic acid esters such as the lipases, solvent, temperature and water content are
    highlighted. Possible enzymatic synthesis using solvent and solvent-free system taking into
    consideration of the difference in these systems involving cost, lipase reusability and efficiency
    is comparatively reviewed. The possible approach for large scale production using various
    enzyme reactor designs is also discussed and re-evaluated.
    MeSH terms: Esters; Lipase; Paper; Pyrones; Solvents; Temperature; Water; Bioreactors; Chemical Phenomena
  2. Wahab Abideen Akinkunmi, Awang Ahmad Sallehin Awang Husaini, Azham Zulkharnain, Tay, Meng Guan, Hairul Azman Roslan
    MyJurnal
    Filamentous fungi such as Fusarium equiseti KR706303 and Penicillium citrinum KR706304
    are capable of sequestering heavy metals from aqueous solutions. In the present study, the role
    play by various functional groups present in the cell wall of F. equiseti KR706303 and P.
    citrinum KR706304 during lead and copper ions biosorption was investigated. The fungal
    biomass was chemically treated to modify the functional groups present in their cell wall. These
    modifications were studied through biosorption experiments. It was found that an esterification
    of the carboxyl and phosphate groups, methylation of the amine groups and extraction of lipids
    significantly decrease the biosorption of both lead and copper ions studied. Therefore, the
    carbonyl, hydroxyl and amide groups were recognized as important in the biosorption of metal
    ions by the tested fungi. The study showed that there was no release of any metal ions from the
    biomass after biosorption, indicating that ion exchange may not be a key mechanism in the
    biosorption of lead and copper ions by these fungi but complexation of metal ions within the
    fungal cell wall.
    MeSH terms: Amides; Amines; Cell Wall; Copper; Esterification; Fusarium; Ion Exchange; Ions; Lipids; Methylation; Penicillium; Phosphates; Hydroxyl Radical; Biomass; Metals, Heavy
  3. Halmi, M.I.E.
    MyJurnal
    The rise in pollution cases globally is expected to increase in line with industrialization.
    Monitoring activities for pollutants have been hampered by the astronomical costs of
    instrumental-based approach. This has resulted in the intense research on low cost
    biomonitoring systems using enzymes, organisms including microorganisms. Only positive
    samples are sent for instrumental analysis; dramatically cutting the cost of instrumental
    analysis. This review attempts to outline and give due recognition to several selected bioassay
    systems that have been tested for their applicability using polluted water samples as a routine
    first line-of-defense. This includes small aquatic organisms-based assays, enzymes especially
    proteases and bacterial-based systems using respiratory dye or luminescence systems as a
    method for toxicant detection.
    MeSH terms: Industrial Development; Biological Assay; Environmental Monitoring; Peptide Hydrolases; Endopeptidases; Water Pollution; Hazardous Substances; Luminescence; Aquatic Organisms
  4. Ling, A.P.K., Halmi, M.I.E., Hussein, S., Ong, S.L.
    MyJurnal
    Ficus deltoidea (or commonly known as mistletoe fig) in various parts of the world mainly
    serves as an ornamental shrub or houseplant and found native mainly in Asia tropical region,
    for example, Malaysia, Indonesia, Philippines and Thailand. Studies on the effect of plant
    growth regulators on cells production from this plant is important as optimization of cells
    production can lead to efficient production of secondary products characterization and
    production. An important aspect of the sigmoidal cells growth curve is the growth parameters.
    In this work, we model the effect of picloram (4-amino-3,5,6-trichloropicolinic acid) on the
    growth kinetics of the cell suspension cultures of Ficus deltoidea according to the modified
    Gompertz model. The adjusted coefficient of determination showed good agreement between
    experimental and predicted data with values ranging from 0.97-0.99. Parameters obtained from
    the fitting exercise were maximum cells growth rate (μm), lag time (l) and maximal cells
    production (Ymax). The results showed that picloram at concentrations of 3 mg/L and above
    were optimal for giving the highest cells growth rate measured as PCV (packed cell volume).
    The parameter growth rate obtained from the modelling exercise will be helpful for additional
    secondary modelling implicating the consequence of media conditions as well as other factors
    on the effect of picloram on the growth rate of cell suspension from this plant.
  5. Hussein, S., Halmi, M.I.E., Ling, A.P.K.
    MyJurnal
    One of the most important preliminary investigation of callus attributes is the growth
    characteristics. Most often than not, callus growth curve is sigmoidal in characteristics. In this
    work, we model callus growth from the seedling of Jatropha curcas L. according to the
    modified Gompertz model from published literature to acquire essential growth constants.
    These growth constants can be obtained with better precision using model such as the modified
    Gompertz. Parameters obtained from the fitting exercise were maximum callus growth rate
    (μm), lag time (l) and maximal callus production (Ymax) of 0.193 d-1, 2.91 days and 0.38 g
    callus/25 mL culture, respectively. Growth parameter constants extracted from the modelling
    exercise will be helpful for additional secondary modelling implicating the consequence of
    media conditions as well as other factors on the growth of callus from this plant.
  6. Siti Nadirah Ismail, Zeiad Amjad Aghwan, Awis Qurni Sazili, Zulkifli Idrus, Azad Behnan Sabow, Ahmed Abubakar Abubakar, et al.
    MyJurnal
    A study was conducted to determine the effects of shackling and cone restraining methods on
    meat quality of broiler chickens slaughtered at two categories of live weight. Fourty Cobb 400
    male broilers were randomly assigned to a 2 × 2 factorial arrangement in a completely
    randomized design with 10 birds of each treatment group. The birds were slaughtered at ≤2 kg
    and ≥2.5 kg live weights using shackling or cone restraining methods. Neither cone nor shackle
    restraining methods affected the pH change of both slaughter weights. Birds weighing ≤2 kg
    subjected to cone method had higher (P
  7. Tan, Hui San, Abdoreza Soleimani Farjam, Goh, Yong Meng, Idrus Zulkifli, Evi Croes, Sarathi Karmakar Partha, et al.
    MyJurnal
    This research was done to evaluate the effect of a commercial exogenous emulsifier
    (polyethylene glycol ricinoleate (PEGR)) with high hydrophilic-to-lipophilic balance (HLB)
    supplementation to broiler chicken diets on growth performance, digestibility of fat and
    apparent metabolisable energy (AME) content in week 1, 3 and 5. A total of 360 one-day-old
    male Cobb broiler chicks were assigned in groups of 30 to 12 battery cages. The chicks were
    randomly assigned to two dietary treatments, with 6 replicate cages per treatment. The diets
    were either standard broiler starter and finisher, with rice bran oil (RBO) as supplemented fat
    source or similar diets + 0.05% emulsifier (RBOV). Feed intakes of RBOV groups significantly
    increased compared to those of RBO groups from week 2 till 4 while body weights of RBOV
    diets significantly increased in week 4 and 5. Both RBOV and RBO groups had similar FCR
    except for week 5. Addition of this strongly hydrophilic emulsifier showed no significant
    difference in fat digestibility of both RC and RV groups but higher AME was noted for the
    treatment than for the control groups at week 5. Therefore, supplementing the exogenous
    emulsifier into a broiler diet enriched with rice bran oil improved body weight and AME
    content at week 5 with minimal effect on fat digestibility.
    MeSH terms: Animals; Body Weight; Chickens; Diet; Dietary Fats; Male; Polyethylene Glycols; Dietary Supplements; Control Groups
  8. Chung, Hung Hui, Azham Zulkharnain
    MyJurnal
    The FADS2 catalyzes the first rate-limiting step in the long chain-polyunsaturated fatty acids
    (LC-PUFAs) biosynthesis pathway by converting -linolenic acid and linoleic acid into
    stearidonic acid and -linolenic acid via the -3 and -6 pathways respectively. In mammals,
    PPAR and SREBP-1c have been implicated in the polyunsaturated fatty acids (PUFAs)
    mediated transcriptional activation of FADS2 promoter. However, in zebrafish, not much is
    known regarding the regulation of fads2 transcriptional regulation. Here, in this study, five
    vectors containing different promoter regions were constructed in order to analyse putative
    promoter activities. Through truncation analysis, it was found that the 1.2 kb promoter was able
    to drive luciferase activity to an approximate 40-fold in HepG2 cells. Upon mutagenesis
    analysis, three sites which are the putative NF-Y, SREBP and PPAR binding sites were found
    to be essential in driving the promoter activity. Lastly, the 1.2 kb fads2 promoter was able to
    direct EGFP expression specifically to the yolk syncytial layer (YSL) when transiently
    expressed in microinjected zebrafish embryos.
    MeSH terms: Animals; Binding Sites; Fatty Acids, Unsaturated; Luciferases; Mammals; Promoter Regions, Genetic; Zebrafish; Fatty Acids, Omega-3; Transcriptional Activation; Mutagenesis; alpha-Linolenic Acid; Linoleic Acid; Peroxisome Proliferator-Activated Receptors; Sterol Regulatory Element Binding Protein 1; Hep G2 Cells
  9. Ramamurthy S, Meng Er H, Nadarajah VD, Pook PCK
    Curr Pharm Teach Learn, 2016 03 21;8(3):364-374.
    PMID: 30070247 DOI: 10.1016/j.cptl.2016.02.017
    OBJECTIVES: To study the impact of open and closed book formative examinations on pharmacy students' learning approach and also to assess their performance and perception about open book (OB) and closed book (CB) systems of examination.

    METHODS: A crossover study was conducted among Year 1 and Year 2 pharmacy students. Students were invited to participate voluntarily for one OB and one CB online formative test in a chemistry module in each year. Evaluation of their learning approach and perception of the OB and CB systems of examination was conducted using Deep Information Processing (DIP) questionnaire and Student Perception questionnaire respectively. The mean performance scores of OB and CB examinations were compared.

    RESULTS: Analysis of DIP scores showed that there was no significant difference (p > 0.05) in the learning approach adopted for the two different examination systems. However, the mean score obtained in the OB examination was significantly higher (p < 0.01) than those obtained in the CB examination. Preference was given by a majority of students for the OB examination, possibly because it was associated with lower anxiety levels, less requirement of memorization, and more problem solving.

    CONCLUSION: There is no difference in deep learning approach of students, whether the format is of the OB or CB type examinations. However, the performance of students was significantly better in OB examination than CB. Hence, using OB examination along with CB examination will be useful for student learning and help them adapt to growing and changing knowledge in pharmacy education and practice.

    MeSH terms: Machine Learning; Anxiety; Books; Education, Pharmacy; Learning; Perception; Pharmacy; Problem Solving; Surveys and Questionnaires; Students, Pharmacy; Cross-Over Studies
  10. Clavadetscher J, Hoffmann S, Lilienkampf A, Mackay L, Yusop RM, Rider SA, et al.
    Angew Chem Int Ed Engl, 2016 12 12;55(50):15662-15666.
    PMID: 27860120 DOI: 10.1002/anie.201609837
    The copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction has proven to be a pivotal advance in chemical ligation strategies with applications ranging from polymer fabrication to bioconjugation. However, application in vivo has been limited by the inherent toxicity of the copper catalyst. Herein, we report the application of heterogeneous copper catalysts in azide-alkyne cycloaddition processes in biological systems ranging from cells to zebrafish, with reactions spanning from fluorophore activation to the first reported in situ generation of a triazole-containing anticancer agent from two benign components, opening up many new avenues of exploration for CuAAC chemistry.
    MeSH terms: Alkynes; Animals; Azides; Catalysis; Copper; Fluorescent Dyes; Polymers; Triazoles; Zebrafish; Cycloaddition Reaction
  11. Dilokthornsakul P, Lee TA, Dhippayom T, Jeanpeerapong N, Chaiyakunapruk N
    Value Health Reg Issues, 2016 May;9:105-111.
    PMID: 27881251 DOI: 10.1016/j.vhri.2016.03.001
    BACKGROUND: To compare health care utilization and cost by asthma severity and type of health insurance in Thailand.

    METHODS: A retrospective cohort study using an electronic database was conducted in patients with asthma. Patients who were diagnosed with asthma from 2009 to 2011, had at least two subsequent health care encounters for asthma during the first six months after the first asthma diagnosis, and had at least 90 days of follow-up were included. The primary outcome was direct health care costs of inpatient and outpatient care. We compared outcomes between groups on the basis of a proxy of severity (mild/moderate severe asthma vs. high severe asthma) and type of health insurance using a multivariable generalized linear model. Covariates such as Patients' demographic characteristics, comorbidities, and concurrent medications were included in the model.

    RESULTS: Among 1982 patients included, the average age was 40.3 ± 24.0 years, with 60.7% being males. A total of 1936 patients had mild/moderate severe asthma, whereas 46 patients had high severe asthma. There were 1293 patients under the Universal Coverage Scheme, 264 patients under Social Security Insurance, and 626 patients under the Civil Servant Medical Benefit Scheme (CSMBS). The average annual cost per patient was $598 ± $871. In adjusted analyses, the health care cost of patients with high severe asthma was $71 higher than that of patients with mild/moderate severe asthma (95% confidence interval $-131 to $274). The cost of patients under the CSMBS was $110 (95% confidence interval $29-$191) higher than that of patients under Universal Coverage Scheme.

    CONCLUSIONS: Health care costs of patients with asthma were substantial and were higher in patients with high severe asthma and patients under the CSMBS.
    MeSH terms: Asthma; Costs and Cost Analysis; Humans; Thailand; Utilization Review
  12. Wang Y, Ghoshal AG, Bin Abdul Muttalif AR, Lin HC, Thanaviratananich S, Bagga S, et al.
    Value Health Reg Issues, 2016 May;9:72-77.
    PMID: 27881264 DOI: 10.1016/j.vhri.2015.11.004
    OBJECTIVES: Asia-Pacific Burden of Respiratory Diseases is a cross-sectional, observational study examining the burden of disease in adults with respiratory diseases across six countries. The aim of this study was to describe health care resource use (HCRU), work impairment, cost burden, and health-related quality of life (HRQOL) associated with respiratory disease in the Asia-Pacific.

    METHODS: Consecutive participants aged 18 years or older with a primary diagnosis of asthma, allergic rhinitis, chronic obstructive pulmonary disease, or rhinosinusitis were enrolled. Participants completed a survey detailing respiratory symptoms, HCRU, work productivity and activity impairment, and HRQOL. Locally sourced unit costs for each country were used in the calculation of total costs.

    RESULTS: The study enrolled 5250 patients. Overall, the mean annual cost for patients with a respiratory disease was US $4191 (SGD 8489) per patient. For patients who reported impairment at work, the mean annual cost was US $7315 (SGD 10,244), with productivity loss being the highest cost component for all four diseases (US $6310 [SGD 9100]). On average, patients were impaired for one-third of their time at work and 5% of their work time missed because of respiratory disease, which resulted in a 36% reduction in productivity. Patients with a primary diagnosis of chronic obstructive pulmonary disease had the greatest impact on HRQOL.

    CONCLUSIONS: In the Asia-Pacific, respiratory diseases have a significant impact on HCRU and associated costs, along with work productivity. Timely and effective management of these diseases has the potential to reduce disease burden and health care costs and improve work productivity and HRQOL.

    MeSH terms: Adult; Asia; Asthma; Cross-Sectional Studies; Efficiency; Humans; Quality of Life; Surveys and Questionnaires; Sinusitis; Health Care Costs; Pulmonary Disease, Chronic Obstructive; Rhinitis, Allergic
  13. Bavanandan S, Ahmad G, Teo AH, Chen L, Liu FX
    Value Health Reg Issues, 2016 May;9:8-14.
    PMID: 27881266 DOI: 10.1016/j.vhri.2015.06.003
    OBJECTIVES: To investigate the 5-year health care budget impact of variable distribution of adult patients treated with peritoneal dialysis (PD) and in-center hemodialysis (ICHD) on government funding in Malaysia.

    METHODS: An Excel-based budget impact model was constructed to assess dialysis-associated costs when changing dialysis modalities between PD and ICHD. The model incorporates the current modality distribution and accounts for Malaysian government dialysis payments and erythropoiesis-stimulating agent costs. Epidemiological data including dialysis prevalence, incidence, mortality, and transplant rates from the Malaysian renal registry reports were used to estimate the dialysis patient population for the next 5 years. The baseline scenario assumed a stable distribution of PD (8%) and ICHD (92%) over 5 years. Alternative scenarios included the prevalence of PD increasing by 2.5%, 5.0%, and 7.5% or decreasing 1% yearly over 5 years. All four scenarios were accompanied with commensurate changes in ICHD.

    RESULTS: Under the current best available cost information, an increase in the prevalent PD population from 8% in 2014 to 18%, 28%, or 38% in 2018 is predicted to result in 5-year cumulative savings of Ringgit Malaysia (RM) 7.98 million, RM15.96 million, and RM23.93 million, respectively, for the Malaysian government. If the prevalent PD population were to decrease from 8% in 2014 to 4.0% by 2018, the total expenditure for dialysis treatments would increase by RM3.19 million over the next 5 years.

    CONCLUSIONS: Under the current cost information associated with PD and HD paid by the Malaysian government, increasing the proportion of patients on PD could potentially reduce dialysis-associated costs in Malaysia.

    MeSH terms: Adult; Budgets; Costs and Cost Analysis; Erythropoiesis; Health Expenditures; Government; Renal Dialysis; Humans; Malaysia; Peritoneal Dialysis; Registries; Incidence; Prevalence
  14. Dilokthornsakul P, McQueen RB, Chaiyakunapruk N, Spackman E, Watanabe JH, Campbell JD
    Value Health Reg Issues, 2016 May;9:99-104.
    PMID: 27881269 DOI: 10.1016/j.vhri.2015.12.003
    Health technology assessment is a form of health policy research that provides policymakers with information relevant to decisions about policy alternatives. Findings from cost-effectiveness analysis (CEA) are one of the important aspects of health technology assessment. Nevertheless, the more advanced method of value of information (VOI), which is recommended by the International Society for Pharmacoeconomics and Outcomes Research and Society for Medical Decision Making Modeling Good Research Practices Task Force, has rarely been applied in CEA studies in Asia. The lack of VOI in Asian CEA studies may be due to limited understanding of VOI methods and what VOI can and cannot help policy decision makers accomplish. This concept article offers audiences a practical primer in understanding the calculation, presentation, and policy implications of VOI. In addition, it provides a rapid survey of health technology assessment guidelines and literature related to VOI in Asia and discusses the future directions of VOI use in Asia and its potential barriers. This article will enable health economists, outcomes researchers, and policymakers in Asia to better understand the importance of VOI analysis and its implications, leading to the appropriate use of VOI in Asia.
    MeSH terms: Clinical Decision-Making; Asia; Cost-Benefit Analysis; Economics, Medical; Health Policy; Surveys and Questionnaires; Technology Assessment, Biomedical; Outcome Assessment (Health Care); Economics, Pharmaceutical; Advisory Committees
  15. Kwa, Siew Kim, Zainab Abdul Majeed, Tan, Kah Nian
    MyJurnal
    Myasthenia gravis (MG) is a rare autoimmune disorder
    characterised by fluctuating and variable combination
    of muscle weakness and fatigue. Most cases are due to
    T-cell mediated autoantibodies against post-synaptic
    acetylcholine receptors (AChR-Ab), thus preventing
    acetylcholine from binding and signalling skeletal
    muscle to contract.1
    The annual incidence is 7-23 new cases per million.1
    It can occur at any age but with two peaks; an earlyonset
    (20-40 years) female-predominant and a late-onset
    (60-80 years) male-predominant peak. MG is classified
    into ocular and generalised (80%). More than half the
    patients initially present with ptosis and diplopia but half
    will progress to generalised disease with involvement of
    bulbar, limb and respiratory weakness. Those presenting
    as generalised MG can also develop eye signs later.1
    It is important to recognise MG early because it is
    highly treatable. Untreated disease leads to permanent
    weakness.2 Treatment reduces mortality from lifethreatening
    myasthenic crisis.1,3 Misdiagnosis leads to
    potentially harmful interventions and inappropriate
    management.4,5 Diagnosis in late-onset MG is easily
    missed2,3,4,5 because of overlapping symptoms with
    other diseases common in the elderly. We report a case
    of delay and misdiagnosis in an elderly patient with
    co-morbidities. (Copied from article).
    MeSH terms: Acetylcholine; Aged; Autoantibodies; Blepharoptosis; Diagnostic Errors; Diplopia; Eye; Female; Humans; Male; Myasthenia Gravis; Receptors, Cholinergic; T-Lymphocytes; Incidence; Muscle Weakness
  16. Kow, Ren Yi, Dhiauddin Hai Ismail, Jamaluddin Shafie, Ruben Jaya Kumar, Nor Hafliza Md Salleh, Low, Chooi Leng
    MyJurnal
    Marjolin’s ulcer is a malignant cutaneous ulcer
    that undergoes transformation from a previously
    traumatized or chronically inflammed skin.1 Causes
    leading to ulcerations can be burn injury, trauma,
    chronic osteomyelitis and varicose ulcers.2 It is named
    after a French surgeon, Jean Nicolas Marjolin, who
    first described the condition in patients who developed
    malignant ulcers from burn scars.3 We report a case of
    a chronic non-healing foot ulcer that has become a
    Marjolin’s ulcer after 12 years. (Copied from article).
  17. Tamara Gien Pooke, Rozi Mahmud, Suraini Mohamad Saini, Yap, Poh Sin, Sharifah Roohi Syed Waseem Ahmad, Harwant Singh
    MyJurnal
    Introduction: The goal of this study was to assess the effectiveness of seated combined extension-compression and transverse load (ECTL) traction as a new method for increasing a reduced lordosis of less than 30 degrees in a Malaysian population between the ages of 18 and 60 years. Possible changes in disc height were measured in accordance with the underlying theoretical framework, that suggests the anterior cervical structures would elongate due to creep over the fulcrum of the traction device.
    Method: This was a single centre, randomised, blinded controlled clinical trial with parallel groups, used to test the superiority of the seated combined ECTL traction together with physiotherapy exercises when compared with the same physiotherapy exercises used as a control. Fifty randomly allocated subjects who completed the forty treatments over the fourteen weeks were analysed using non-parametric tests for changes in outcomes.
    Results: There were no significant changes in outcomes for disc height changes seen in this study. The findings of a greater overall increase in posterior disc height changes compared with anterior disc height changes were in contrast with the proposed underlying theoretical framework for this type of ECTL traction. The greater height changes occurring in the control group were also unexpected.
    Conclusion: The findings in this study of the contrasting changes in disc height of greater posterior than anterior height changes, question the underlying theoretical framework as postulated for this type of traction.
    MeSH terms: Animals; Exercise Therapy; Goals; Humans; Lordosis; Malaysia; Orthopedic Equipment; Posture; Traction; Control Groups
  18. Lim, Swee Geok, Yam, Siew Woan
    MyJurnal
    Introduction: Patient falls has been identified as one
    of the major issues in today’s health care despite efforts
    taken in preventing such incidents from happening
    (Cox et al., 2014). Patient falls can be prevented by
    using fall risk assessment tools such as Morse Fall Scale.
    Morse Fall Scale was implemented in the year 2014 in a
    private hospital in Malaysia but the patient fall rate did
    not decrease.

    Objective: The research objective is to determine the
    nurses’ level of knowledge and competency in the use
    of the Morse Fall Scale as an assessment tool in the
    prevention of patient falls.

    Method: A quantitative, descriptive, cross-sectional
    research design was conducted with 100 registered nurses
    from a private hospital in Selangor, Malaysia. Universal
    sampling technique was used to recruit the nurses.
    Results: The registered nurses had a moderate level
    of knowledge (M = 7.72; SD = 1.72) and competency
    (scoring Morse Fall Scale, M = 4.75; SD = 1.26;
    planning intervention, M = 13.19; SD = 1.89) in using
    the Morse Fall Scale.

    Conclusion: It is recommended that a review of the
    training programme on the use of the Morse Fall Scale
    be implemented in a more structured manner.
  19. Siew, Wei Fern, Loh, Cindy Sze Nee
    MyJurnal
    Background: Continuing professional development (CPD) is a primary strategy for nurses to keep abreast with the rapid changes in the health care practices of current times. Evidence has shown that nurses lack the initiative to take up the additional CPD offered by their organisation and have to be persuaded to do so once they have achieved the minimum 25 points of CPD mandated by Malaysia Professional Regulatory Board of Nursing (MNB).
    Objective: To determine the extent to which nurses from a private hospital in Melaka will participate in CPD and the challenges affecting them from participating in CPD
    upon achieving the mandatory CPD points specified by MNB.
    Methods: This is a cross-sectional descriptive survey. A sample of 188 registered nurses (RNs) from a private hospital in Melaka was recruited via purposive sampling technique to complete a self-reporting questionnaire. The instrument which was adapted and used with permission was pilot-tested for reliability and validated by content experts to ensure its suitability for this local study.
    Results: The survey showed that 82.4% of the registered nurses (RNs) had attained additional CPD points apart from the minimum 25 CPD points stipulated by MNB. The findings on RNs reading journals or engaged in distance learning programmes were not encouraging as the percentages were only 31.4% and the latter, 9%. In-service talks, grand round discussions and online sources of continual nursing education that do not require the RNs to be away from their work duties were the most frequent type of CPD activities participated by the RNs as compared to conferences, workshops, distance learning programmes or post basic courses. The top 3 challenges that affect RNs’ participation in CPD were time constraint (90.4%), work commitments (85.6%) and difficulty in getting nominated (53.7%) to attend the CPD activities of their choice.
    Conclusions: The results of this study highlighted the respondents’ views to the management on the importance to align the approach of sponsoring CPD courses according to the nurses’ needs in order to meet their context of practice. The management also ought to take into consideration the identified challenges encountered by the nurses to participate in CPD upon achieving their mandatory CPD points specified by MNB.
    MeSH terms: Adult; Cross-Sectional Studies; Education, Continuing; Humans; Malaysia; Nurses; Hospitals, Private
  20. Raja Ariffin RN, Abdul Mutalib M, Mohd Satar N, Hanafi H, Othman A, Tumin M, et al.
    MyJurnal
    Background: There is a lack of information on the practice of family planning among Muslim women in New York City in the United States of America (USA) [hereinafter known as “Muslim women residing in the United States” (MWRIU)], Tehran in the Islamic Republic of Iran (IRI) and Kuala Lumpur, Malaysia.
    The limited figures on this issue are either outdated or mere estimates. The importance of sexual and reproductive health of Muslim women is expected to have massive effects on the social and economic progress of developing countries like the IRI and Malaysia. It is also expected to have imperative impacts on the attempts to empower the MWRIU community and enhance their health status to meet the national standards.
    Objective: The study objective is to explore and compare the practice of family planning, namely on contraceptive use and abortion among Muslim women in 3 major cities of different countries.
    Methodology: A survey of 379, 377 and 380 respondents from New York City, Tehran and Kuala Lumpur respectively was conducted in 2013 using self-administered questionnaires.
    Results: There were significant differences in contraceptive and abortion practices across these countries (P<0.01). While a significant 86.6% of Iranian and 66.2% of the MWRIU used contraception, only 22.9% of the Malaysian women did so. For abortion, 13.6% of the MWRIU and 6.3% of the Malaysian respondents had abortion at least once; while only 22% of Iranians revealed their abortion history, totaling 32.1% of them who had abortion. Financial problems and having an unsupportive husband were among the major factors hindering their practice of healthy family planning.
    Conclusion: Educational campaigns should be promoted to increase the awareness on the permissibility of family planning in Islam, as well as on sexual and reproductive rights.
    MeSH terms: Abortion, Induced; Adult; Contraception; Cross-Sectional Studies; Female; Humans; Iran; Islam; Health Knowledge, Attitudes, Practice; Malaysia; Religion; United States
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