Browse publications by year: 2020

  1. Ahmad Badruridzwanullah Zun, Mohd Ismail Ibrahim, Anees Abdul Hamid
    MyJurnal
    Introduction: Primary health care plays an important role in healthcare systems. In Malaysia, One (1) Malaysia Clinic (now known as Community Clinic since 2018) was established in 2010 aims to increase healthcare services accessibility within the poor urban population. The aim was to look at the effectiveness of One (1) Malaysia Clinic as a new form of public primary health clinic by looking at expectations and perceptions of the quality of the provided services by the patients. Method: It applied a cross sectional study involving nine clinics in of the busiest district in Kelantan namely, Kota Bharu district. 386 respondents which were Malaysian citizen, 18 years old and above were involved in this study. The survey used Malay validated SERVQUAL questionnaire. The Service Quality (SQ) gap was calculated. Result: The empathy dimension obtained the highest expectation and perception score, while the tangi- ble dimension has the lowest expectation and perception score. In all SERVQUAL dimension, the expectations and perceptions of the service provided was significantly different with P < 0.001. The most critical dimension identified was tangible dimension as it has the largest negative SQ gap score. Conclusion: Negative gaps for all SERVQUAL dimensions and individual items indicated that provided services at One (1) Malaysia Clinic still could not fulfilled the patient’s expectation. A continuous improvement program is needed especially on tangible dimension in deliv- ering a quality healthcare services.
    MeSH terms: Adolescent; Ambulatory Care Facilities; Cross-Sectional Studies; Delivery of Health Care; Empathy; Health Services; Humans; Malaysia; Motivation; Perception; Primary Health Care; Surveys and Questionnaires; Urban Population
  2. Ruzawani Ruslan, Munirah Mohd Adnan, Normastura Abd Rahman
    MyJurnal
    Introduction: Smoking is a common risk factor for periodontal disease and other chronic diseases. This study was conducted to determine the prevalence of smoking among army personnel and its association with periodontal health status. Methods: A cross-sectional study was carried out among randomly selected 233 army personnel in 8th Brigade Infantry, Kelantan. A face validated self-administered Bahasa Malaysia questionnaire was used for data col- lection. Periodontal examination was done using Community Periodontal Index (CPI) and coded as ‘0’ for healthy; ‘1’ for bleeding observation; ‘2’ for detection of calculus; ‘3’ for probing of 4-5mm pocketing and ‘4’ for probing of 6mm or more pocketing. Results: All respondents (n=233) were male, the majority (92.7%) Malays, not married (60.5%) with the mean (SD) age of 25.8 (5.06) years. The prevalence of smoking among army personnel was 76.0% (95% CI: 70.4, 81.5). Almost all (97.4%) have some degree of periodontal disease. The non-smoker, ex-smoker and smoker groups were highest for having calculus with a percentage of 40.5%, 57.1%, and 57.1%, respectively. No significant association was found between smoking status (ever-smoker and non-smoker) and periodontal pocketing (CPI 0-2 and CPI 3-4) (p=0.960). However, the ever-smokers (93.2%) significantly higher percentage for the need of invasive treatment (CPI >2) compared to the non-smokers (76.2%) (p=0.002). Conclusion: The prevalence of smok- ing among army personnel in North-East Malaysia was high, with most of them have some degree of periodontal disease. Smoking cessation intervention should be strategized in the military community to reduce the burden of care for chronic diseases.
    MeSH terms: Calculi; Chronic Disease; Cross-Sectional Studies; Health Status; Humans; Malaysia; Male; Military Personnel; Periodontal Diseases; Periodontal Index; Periodontal Pocket; Risk Factors; Smoking; Prevalence; Smoking Cessation
  3. Mazlan NW, Clements C, Edrada-Ebel R
    Mar Drugs, 2020 Dec 21;18(12).
    PMID: 33371387 DOI: 10.3390/md18120661
    The discovery of new secondary metabolites from natural origins has become more challenging in natural products research. Different approaches have been applied to target the isolation of new bioactive metabolites from plant extracts. In this study, bioactive natural products were isolated from the crude organic extract of the mangrove plant Avicennia lanata collected from the east coast of Peninsular Malaysia in the Setiu Wetlands, Terengganu, using HRESI-LCMS-based metabolomics-guided isolation and fractionation. Isolation work on the crude extract A. lanata used high-throughput chromatographic techniques to give two new naphthofuranquinone derivatives, hydroxyavicenol C (1) and glycosemiquinone (2), along with the known compounds avicenol C (3), avicequinone C (4), glycoquinone (5), taraxerone (6), taraxerol (7), β-sitosterol (8) and stigmasterol (9). The elucidation and identification of the targeted bioactive compounds used 1D and 2D-NMR and mass spectrometry. Except for 6-9, all isolated naphthoquinone compounds (1-5) from the mangrove plant A. lanata showed significant anti-trypanosomal activity on Trypanosoma brucei brucei with MIC values of 3.12-12.5 μM. Preliminary cytotoxicity screening against normal prostate cells (PNT2A) was also performed. All compounds exhibited low cytotoxicity, with compounds 3 and 4 showing moderate cytotoxicity of 78.3% and 68.6% of the control values at 100 μg/mL, respectively.
    MeSH terms: Antiprotozoal Agents/isolation & purification*; Antiprotozoal Agents/pharmacology; Cell Line; Furans/isolation & purification*; Furans/pharmacology; Humans; Naphthoquinones/isolation & purification*; Naphthoquinones/pharmacology; Plant Extracts/isolation & purification*; Plant Extracts/pharmacology; Trypanosoma brucei brucei/drug effects*; Trypanosoma brucei brucei/physiology; Avicennia*
  4. Yong Kang Cheah, Mohd Azahadi, Noor Safiza Mohamad Nor, Siew Nooi Phang, Noor Hazilah Abd Manaf
    MyJurnal
    Introduction: This study examined how waist circumference (WC) varied across sociodemographic characteristics of Malaysian adults using a nationally representative data. Methods: Data from the Malaysian Adult Nutrition Survey 2014 (n = 2696) was used. In the sample, 46.55% were males and 53.45% were females. The outcome variable was WC. Waist circumference was categorised into four ordinal outcomes: very low, low, high and very high. The ex- planatory variables were age, monthly individual income, education, gender, marital status, ethnicity, employment status and household location. Ordered probit models were utilised. Results: The majority of males had a low WC (54.66%), and only a small proportion had a very high WC (0.96%). Similarly, a high proportion of females had a low WC (55.59%), and only 1.94% had a very high WC. Younger males were more likely to have a high WC than their older counterparts. Males who had monthly income of RM2000-2999 or RM3000-3999 were more likely to have a high WC compared with those who had monthly income of RM999. Chinese and Indian males were more likely to have a high WC than Bumiputera males. For females, those who were married, widowed/divorced and Bu- miputera were likely to have a high WC. Conclusion: WC was associated with various sociodemographic profiles of males and females. In particular, there were positive associations between the likelihoods of having a high WC and younger age group, higher income, Chinese, Indian, and being married. Our findings provided policy makers with better information on formulating intervention measures.
    MeSH terms: Administrative Personnel; Adult; Divorce; Educational Status; Employment; Ethnic Groups; Female; Humans; Male; Marriage; Nutrition Surveys; Marital Status; Widowhood; Asian Continental Ancestry Group; Waist Circumference
  5. Nor Hazliana Harun, Rabiatul Basria S.M.N. Mydin, Khairul Anuar Shariff, Nur Adila Rosdi, Davamunisvari Rames
    MyJurnal
    Introduction: This study aims to investigate different residue sizes of β-tricalcium phosphate (β-TCP) micro-granules as carriers to assess antibacterial activity and drug-control release behavior of ampicillin (AMP-) and antimycotic (AMC-). Incorporation of antibiotic into the β-TCP micro-granules and it sustain release behavior could be used as alternative solution to reduce the risk of osteomyelitis and bone infections risks. Methods: Three different residue sizes (less than 300 µm, 300 µm and 600 µm) were prepared and coated with antibiotics solution (20 µg/µl of ampi- cillin and 100X antimycotic solution) by using two methods; dip and stream coating. After 72 h, 1.5 mL of distilled water was added to the treated (β-TCP) micro-granules at two different pH value (5.0 and 7.4). The extracted solution was further analyzed by Kirby Bauer disc diffusion test and spectrophotometer assay. Results: The solution con- taining AMC-(β-TCP) micro-granules with the size of 300 µm residue produced the largest inhibition zones against Escherichia coli (E. coli). All residue sizes coated with AMP- showed no antibacterial activity against both strains; Staphylococcus aureus (S. aureus) and E.coli. Additionally, the release behavior of AMC-(β-TCP) micro-granules was found not depending on the pH, but on the size of residue. Complete drug release was rapidly observed within 48
    h. Conclusion: Based on this findings, it showed AMC-(β-TCP) micro-granules had an antibacterial activity against Gram-negative strain. Specifically, it can reduced the growth rate of E. coli and the rapid release behavior of AMC- (β-TCP) micro-granules help in minimizing the risk-infections in early stage of implantation.
    MeSH terms: Adenosine Monophosphate; Ampicillin; Anti-Bacterial Agents; Calcium Phosphates; Pharmaceutical Preparations; Escherichia coli; Hydrogen-Ion Concentration; Osteomyelitis; Staphylococcal Infections; Staphylococcus aureus; Water; Rivers; Drug Liberation
  6. Rafidah Aga Mohd Jaladin, Janet Ann Fernandez, Nur Ain Sumaiyah Abdullah, Adelina Asmawi
    MyJurnal
    Introduction: Single parent families, especially, those headed by single mothers are becoming increasingly common around the world especially in Malaysia. Single mothers generally suffer from poorer mental health, job discrimina- tion, abuse and neglect. Hence, they often experience high anxiety, depression, and stress. This calls for research to empower their mental wellbeing. The present study examined the effectiveness of creative group counselling in increasing self-compassion, and decreasing depression, anxiety and stress among single mothers. Methods: A qua- si experimental pre-test post-test design was employed in the study. Research participants consisted of 36 single mothers placed in two experimental and two control groups. The instruments used were Self-Compassion Scale and Depression Anxiety and Stress Scale. A self-compassion module was developed that comprised creative therapeutic activities which was administered to the participants in the experimental groups via a 7-session group counselling programme. Participants in the control groups, on the other hand, took part in guidance activities. Semi structured in- terviews were also performed to gather feedback on the impact of the creative intervention from three single mothers. Results: Findings revealed that creative group counselling successfully increased the level of self-compassion among single mothers. Additionally, the depression, stress and anxiety scores of single mothers were lower after joining the group counselling programme. Furthermore, three themes emerged from the present study which are i) be kind to oneself; ii) mistakes are part of life; and iii) self-transformation. Conclusion: It is evident that the implementation of creative group counselling improves the mental wellbeing of single mothers.
    MeSH terms: Anxiety; Anxiety Disorders; Counseling; Depression; Empathy; Feedback; Female; Humans; Malaysia; Mental Health; Mothers; Stress, Psychological; Single-Parent Family; Control Groups
  7. Norfarhana Mohd Anuar, Barakatun Nisak Mohd Yusof, Farah Yasmin Hasbullah, Siti Nur’Asyura Adznam, Zuriati Ibrahim, Nor Fadhlina Zakaria, et al.
    MyJurnal
    Introduction: Low glycemic index (GI) diet is recommended as part of medical nutrition therapy for the management of gestational diabetes mellitus (GDM). While the clinical benefits are evident, data assessing knowledge of the GI concept among women with GDM are scarce. This was a needs assessment study to determine the level of knowl- edge about the GI concept among women with GDM. Methods: Using a cross-sectional design, we included 85 women with GDM (mean age: 30.6 ± 4.0, pre-pregnancy BMI: 24.8 ± 4.1 kg/m2, gestational age: 34.0 ± 4.0 weeks) from Hospital Serdang, Malaysia. Knowledge about the GI concept was assessed using a developed questionnaire. Additional questions on GDM were assessed using Gestational Diabetes Mellitus Knowledge Questionnaire (GDM- KQ). Subjects with less than 50%, 51-74%, and more than 75% total score were categorized as having poor, fair, and good knowledge levels, respectively. Results: The mean knowledge score obtained by the subjects was 12.8 ± 3.5. More subjects scored correctly for GDM-related knowledge (68.2%). More than half (58.8%) had heard about the GI concept previously and 55.3% understood the definition of GI. The average knowledge score about the GI con- cept was 55.6%; subjects scored highest on the influence of different carbohydrates (teh tarik versus milk) on blood glucose level (87.1%). However, the majority of the subjects had fair knowledge level (62.4%). Conclusion: Women with GDM had moderate knowledge about the GI concept. Results of the needs assessment served as preliminary data for the development of a GI-based nutrition education program in Malaysia.
    MeSH terms: Animals; Blood Glucose; Cross-Sectional Studies; Diet; Female; Gestational Age; Health Education; Hospitals; Humans; Infant; Malaysia; Milk; Pregnancy; Surveys and Questionnaires; Body Mass Index; Diabetes, Gestational; Needs Assessment; Glycemic Index; Nutrition Therapy
  8. Siti Noor Syarma Mohd Sharif, Mohd Adzim Khalili Rohin, Norhayati Abd Hadi
    MyJurnal
    Introduction: cAMP Response Element Binding (CREB) and Brain Derived Neurotrophic Factor (BDNF) protein levels tend to be a critical mediator for the beneficial effects of diet on neurogenesis and cognitive function. Increased fruit intake has been associated with improved cognitive function. However, in Malaysia, most adolescents still haven't met the recommended intake of fruits and far less is known on how their adequacy of fruit intake can be affected to their protein levels of CREB and BDNF. Methods: A cross sectional study was done on 352 students aged 14 and 16 years old involving 11 secondary schools in Kuala Terengganu, Marang and Hulu Terengganu Districts. A validated MyUM adolescent FFQ was used for fruit intake assessment. Blood sample to determine the level of CREB and BDNF proteins. Results: A total of 53.7% of adolescents consumed an adequate intake ( 2 servings/day) of fruits. Serum level BDNF was significantly (p
    MeSH terms: Adolescent; Aged; Cognition; Cross-Sectional Studies; Diet; Fruit; Humans; Malaysia; Schools; Students; Brain-Derived Neurotrophic Factor; Response Elements; Neurogenesis
  9. Manah Chandra Changmai, Mohammed Faruque Reza, Zamzuri idris, Regunath Kandasamy, Kastury Gohain
    MyJurnal
    Introduction: Intracranial brain tumour like meningiomas and glioblastomas are most prevalent tumour. The metas- tasis to the brain is one of the major issues in the tumours of the central nervous system. The diagnosis of metastatic and primary brain tumour is incomprehensible with standard magnetic resonance imaging (MRI). The magnetic res- onance spectroscopy (MRS) is basically performed in standard clinical setting for diagnosing and tracking the brain tumour. Method: It is a retrospective study containing 53 patients with MRS. The patients with metastatic tumour (n=10), glioblastomas (n=8) and meningiomas (n=20) are included in the study. Single voxel technique is applied in the tumour core to determine the metabolites. The tumour N-acetyl aspartate (NAA), Choline (Cho), Creatine (Cr), Lactate, Alanine and lipids were analysed. The ratios of NAA/Cr, Cho/NAA and Cho/Cr were recorded and com- pared between the three tumours. The metabolites were detected between short echo time (TE) to long echo time (TE) during MRS. Results: There is a sharp fall of NAA peak in metastatic tumour. The resonance of creatine, lactate and alanine is higher in glioblastomas. A high lipid mean value of 3.13(0.17) is seen in metastatic tumour. The ROC curve shows a low NAA/Cr specificity of 46.7%, high sensitivity of 83.3% in Cho/NAA and Cho/Cr ratio. Conclusion: The metabolic profiles of metastatic brain tumour, glioblastomas and meningioma illustrate a divergence in their description that will assist in planning therapeutic and surgical intervention of these tumours.
    MeSH terms: Alanine; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Glioblastoma; Humans; Lipids; Magnetic Resonance Imaging; Meningeal Neoplasms; Meningioma; Reference Standards; Retrospective Studies; ROC Curve; Spectrum Analysis; Lactic Acid; Metabolome
  10. Aiemeeza Rajali, Siti Fauzza Ahmad
    MyJurnal
    Introduction: The compatibility of denture cleanser is crucial in the prevention of failure of adhesion between silicone soft liner and acrylic denture base, thus ensuring the durability of the prosthesis. This scanning electron microscope (SEM) study was to determine the mode of failure and measured the gap formation between silicone soft liners and Polymethylmethacrylate (PMMA) denture base after immersion in denture cleansers. Methods: A total of 135 specimens of PMMA denture base lined with three different silicone soft liners (GC Reline Soft, Mollosil and Tokuyama Sofreliner Tough) were immersed into denture cleansers (Polident® and Stearadent) daily and stored in distilled water at 37±1°C. Specimens were examined and sectioned at 2.5mm and 5.0mm from the margin after 1 day, 30 days and 90 days before analyzed. Results: No significant difference detected in the mode of failure and gap formation after one-day immersion. Adhesive failure was the commonest failure at the margin after 30 days (71.11%) and after 90 days (95.56%). However, 33.33% of specimens showed mixed failure at 5.0mm sectioned after 90 days. A significant difference of gap formation was demonstrated from Mollosil in Steradent at the margin and at 2.5 mm sectioned after 30 days and after 90 days (p
    MeSH terms: Adhesives; Borates; Denture Bases; Denture Cleansers; Denture Liners; Immersion; Microscopy, Electron, Scanning; Phosphates; Silicones; Sodium Chloride; Sulfates; Water; Polymethyl Methacrylate
  11. Koehn JZ, Quinn EL, Otten JJ, Allison EH, Anderson CM
    J Agric Food Syst Community Dev, 2020;10(1):171-189.
    PMID: 33996191 DOI: 10.5304/jafscd.2020.101.027
    Along the U.S. West Coast, sustainable management has rebuilt fish stocks, providing an opportunity to supply nutrient-rich food to adjacent coastal communities where food insecurity and diet-based diseases are common. However, the market has not successfully supplied locally sourced seafood to nutritionally vulnerable people. Rather, a few organizations make this connection on a limited scale. We used a "positive deviant" approach to learn how these organizations' efforts developed, how they overcame challenges, and what conditions enabled their interventions. We found that organizations in these positive deviant cases provided fish from a wide variety of species and sources, and distributed them through different channels to a diversity of end consumers. A key factor facilitating success was the ability to negotiate a price point that was both profitable and reasonable for organizations supplying nutritionally vulnerable or low-income consumers. Further-more, securing access to grants overcame initial costs of establishing new supply channels. All cases highlighted the importance of individual champions who encouraged development and cultural connections between the initiative and the nearby community. Organizations overcame key challenges by establishing regulations governing these new channels and either using partnerships or vertically integrating to reduce costs associated with processing and transport. Oftentimes training and education were also critical to instruct workers on how to process unfamiliar fish and to increase consumer awareness of local fish and how to prepare them. These lessons illuminate pathways to improve the contribution of local seafood to the healthy food system.
  12. Afiq Izzudin A Rahim, Mohd Ismail Ibrahim
    MyJurnal
    Introduction: Initially, studies showed that graphic warning signs (GWSs) on cigarette packages encouraged smok- ing cessation. However, there have been recent concerns over the effectiveness of GWSs to change smoker percep- tions and behavior over time. Our goals were to assess the latest perceptions of GWSs among smokers in Kelantan and to determine the factors associated with them. Methods: This cross-sectional study was conducted among re- spondents who attended outpatient clinics in a teaching hospital in Kelantan. Their perceptions were analyzed with a validated Malay questionnaire containing four domains: fear, influence, credibility, and picture content. Results: The average smoking age was 17 (3.04) years old. The mean smoking time was 11 (7.49) years. The average daily cigarettes smoked was 8 (6.26). Most respondents perceived low levels of fear (83%), poor picture content (65.5%), low influence (87.6%), and low levels of credibility (70.1%) in GWSs. Those with low levels of education were significantly associated with poor perceptions of GWSs. Conclusion: Despite vigorous efforts by the government to discourage smoking in Kelantan, smokers still poorly perceive GWSs. More effective health-promotion strategies are essential to influence smokers in this area.
    MeSH terms: Adolescent; Ambulatory Care Facilities; Cross-Sectional Studies; Fear; Goals; Government; Hospitals, Teaching; Humans; Malaysia; Perception; Product Labeling; Surveys and Questionnaires; Smoke; Smoking; Health Behavior; Tobacco Products
  13. Syarifah Nurul Ain, Chua Sze Hung, Aida Nurbaini Arbain, Sarah Marilyn Amin, Teoh Eu Vin, Ferro Firdaus Ibrahim, et al.
    MyJurnal
    Introduction: Doctors are known to deal with high occupational stress, causing increased risk of depression, anxi- ety and stress.Nevertheless, the prevalence and associatedfactors of depression, anxiety and stress among registered doctorsworking in 24 public hospitals in Sabah, Malaysia are not known yet. Methods: This cross-sectional study was conducted using convenient sampling from September-October 2018. The data of 21-item Depression Anxiety Stress Scale (DASS-21) was collected via online link anonymously. Results: Among 314 doctors, majority of them were females (62.1%), mean age 29 (SD 2.72), non-Sabahan (82.8%), Malays (46.8%), not married (78.3%) and medical officers (93.6%). Prevalence of severe/extremely severe anxiety symptoms was 27.4%,depression (22.9%) and stress (18.5%). Doctors perceiving themselves to be depressed, anxious and/or stressed were more likely to develop the corresponding symptoms. Females and Chinese were twice more likely to report anxiety symptoms. Being married had protective effect against depressive symptoms, while working in same hospital for longer time had a significant but weak protective effect against anxiety and stress symptoms. Conclusions: Mental health issue among doctors is substantial and need to be addressed effectively for the benefit of their life, patients and country.
    MeSH terms: Adult; Anxiety; Anxiety Disorders; Cross-Sectional Studies; Depression; Female; Hospitals, Public; Humans; Malaysia; Marriage; Mental Health; Prevalence; Asian Continental Ancestry Group
  14. Mohd Zarawi Mat Nor, Najib Majdi Yaacob
    MyJurnal
    Introduction: The USM Pre-clinical medical students’ guidance and counselling needs questionnaire (USM-MS- GCN-Q) is an English-language guidance and counselling needs questionnaire which was developed specifically for pre-clinical medical students. The aim of this study is to highlight the construct validity of USM-MSGCN-Q among pre-clinical medical students. Methods: In June 2017, a cross-sectional study on 208 pre-clinical medical students was conducted in Universiti Sains Malaysia (USM). This self-administered USM-MSGNC-Q consisted of four constructs and 20 items with a 5-point Likert scale within each item. A confirmatory factor analysis was em- ployed to test the hypothesized measurement model. Results: The final measurement model fitted the data well. The four-factor model initially consisted of 20 items however, it was reduced to 18 items with the goodness of fit indices suggesting good model fit (RMSEA 0.89, GFI .915 and ChiSq/df 2.642). Internal consistency reliability (Cronbach’s alpha) was 0.879 for self-leadership skills, 0.929 for communication skills, 0.871 for learning skills, and 0.870 for psychological coping skills. The overall Cronbach’s value was 0.922. Respective composite reliability values were 0.879,0.952,0.879 and 0.835 while the Average Variance Extracted values were 0.729, 0.911, 0.595 and 0.630. Conclusion: This study has confirmed that self-leadership, communication, learning and psychological coping skills were the components of guidance and counselling needs which influences the effectiveness of guidance and coun- selling sessions with pre-clinical medical students.
    MeSH terms: Adaptation, Psychological; Communication; Counseling; Cross-Sectional Studies; Factor Analysis, Statistical; Humans; Language; Leadership; Learning; Malaysia; Surveys and Questionnaires; Students, Medical; Reproducibility of Results
  15. Normina Ahmad Bustami, Yu Bin Ho, Chung Keat Tan, Ahmad Zaharin Aris, Eugenie Sin Sing Tan
    MyJurnal
    Introduction: Consumption of Chinese Herbal Medicine (CHMs) have escalated globally. They are preferred treat- ment for minor diseases or disorders. In Malaysia, CHMs are common home remedies during pregnancy and postpar- tum. Angelica sinensis (Danggui) is a staple CHMs during postpartum for purpose of nourishing blood and resolving stasis. Concerns are raised over possible heavy metals toxicity. Objective: This study aims to (i) determine Danggui consumption among postpartum mothers, (ii) quantify its heavy metals level, namely Lead (Pb), Cadmium (Cd), Ar- senic (As) and Chromium (Cr) and (iii) determine health risks of Danggui consumption among mothers. Methods: A cross-sectional study involving 112 postpartum mothers was carried out in Kuala Lumpur. Danggui samples were collected from nine districts in Kuala Lumpur (Segambut, Seputeh, Cheras, Kepong, Bandar Tun Razak, Titiwangsa, Setiawangsa, Batu and Lembah Pantai). Heavy metals were extracted using microwave digester and analysed using Inductively coupled plasma mass spectrometry (ICPMS). Hazard Quotient (HQ) was used to determine non-carcino- genic health risks for herbal medicine consumption. Results: Danggui was consumed by 19.6% of mothers (n=22). Among them, incidence of jaundice was 63.6% and need for phototherapy was 40.9%. Heavy metals contamina- tions were found in the decreasing order of Cr > As > Pb > Cd with median (interquartile) of 3996.3 (2805.6) μg/ kg, 128.3 (56.7), 98.6 (99.1) and 37.0 (35.0) respectively. No non-carcinogenic health risks were found for all four metals. Conclusion: Alarming concentrations of heavy metals were quantified in Danggui warranting for further in- vestigation to safeguard health of postpartum mothers.
    MeSH terms: Cadmium; Chromium; Cross-Sectional Studies; Drugs, Chinese Herbal; Female; Humans; Jaundice; Lead; Malaysia; Medicine, Traditional; Microwaves; Mothers; Phototherapy; Plants, Medicinal; Plasma; Pregnancy; Mass Spectrometry; Incidence; Metals, Heavy; Herbal Medicine; Angelica sinensis; Postpartum Period
  16. Wan Ling Chew, Kaur Satvinder, Serene En Hui Tung, Ai Ni Teoh, Choon Ming Ng
    MyJurnal
    Introduction: Early environmental factors play a major role in shaping the health of an individual. Dietary prefer- ence and habits shaped by parental feeding practice during childhood are likely to persist into adulthood which further determines body weights status. This study aimed to determine the retrospective child feeding practices asso- ciated with obesity risk in young adults. Methods: This was a retrospective cross-sectional study with 176 university students in Kuala Lumpur. Data of maternal age, gestational age and feeding practices were collected retrospectively using Child Feeding Questionnaire (CFQ). Subject’s current socio-demographic data was collected and anthropo- metric measurements were taken using standard protocol. Results: Around 22% of the subjects were overweight/ obese. No significant association was found between child feeding practices with maternal age. A significant asso- ciation (p
    MeSH terms: Adult; Body Weight; Child; Cross-Sectional Studies; Demography; Diet; Feeding Behavior; Gestational Age; Habits; Humans; Maternal Age; Obesity; Parents; Surveys and Questionnaires; Reference Standards; Retrospective Studies; Students; Universities; Overweight; Young Adult
  17. Hidani Hasim, Che Badariah Abd Aziz, Siti Qusyasyiah Ahmad Suhaimi, Mahaneem Mohamed, Idris Long, Rahimah Zakaria
    MyJurnal
    Introduction: Increased nociceptive responses were shown in the offspring of prenatally stressed rats. Reports have demonstrated the anti-nociceptive effects of Tualang honey in the rat offspring. The present study was done to de- termine whether the modulation of nociceptive behaviour by Tualang honey was mediated by modulating changes in the histology, oxidative stress parameters and N-methyl-D-aspartate (NMDA) receptors in the thalamus of the rat offspring. Methods: Eighteen Sprague Dawley pregnant rats were randomly assigned to control (C), stress (S) and stress-treated with Tualang honey (SH) groups. Stress was given in a form of restraint stress.Tualang honey was given to SH group from first day of pregnancy until delivery. Thirty-three adult male offspring were subjected to formalin test before they were sacrificed. Nociceptive behaviour score, number of neurons, level of oxidative stress parameters and NMDA receptors in the thalamus were analysed by using one-way ANOVA. Results: The study demonstrated a significant decrease in mean nociceptive behaviour score (p
    MeSH terms: Analysis of Variance; Animals; Female; Honey; Male; Neurons; Pain Measurement; Pregnancy; Restraint, Physical; Thalamus; Receptors, N-Methyl-D-Aspartate; N-Methylaspartate; Rats, Sprague-Dawley; Oxidative Stress; Rats
  18. Umi Mardhiyyah Mat Ali, Asma Alhusna Abang Abdullah, Nurul Asyikin Yahya
    MyJurnal
    Introduction: Delivering oral hygiene instruction is one of the integral parts of orthodontic treatment. However, there is scarce information regarding the impact of audiovisual method on knowledge retention among orthodontic patients. This study aimed to assess knowledge retention of the patient after instruction delivered in audiovisual (AV) method and compare it to the standard written and verbal (WV) method. Methods: This prospective clinical trial was conducted on 60 patients aged 13 to 40 years. They were randomized into the audiovisual group (n=30) and written & verbal group (n=30). Patients’ knowledge retention was measured using a self-administered questionnaire in Google form, immediately after instruction given as short-term retention and long-term retention for three time- point, i.e., 1-month, 3-month, and 6-month. Results: There was a significant improvement in knowledge for both AV and WV methods at immediate and 1-month assessment and the knowledge retained until 6-month follow up. The AV method demonstrated a significantly higher increase in knowledge retention at immediate and 1-month than the WV method. Conclusion: The AV method was significantly more effective in improving patient's knowledge reten- tion compared to the written & verbal methods. Repetition of instruction also influence the retention of knowledge.
    MeSH terms: Adolescent; Adult; Aged; Dental Care; Follow-Up Studies; Humans; Oral Hygiene; Prospective Studies; Surveys and Questionnaires; Reference Standards; Writing; Health Behavior; Young Adult
  19. Aisha Khodijah Kholib Jati, Suharni Mohamad, Zeehaida Mohamed, Wan Haslindawani Wan Mahmood, Wan Muhamad Amir W Ahmad, Wan Suriana Wan Ab Rahman1
    MyJurnal
    Introduction: This preliminary cross-sectional study aimed to investigate the prevalence of toxoplasmosis among blood donors in Kelantan, Malaysia. Methods: A total of 56 blood donors were screened by an enzyme-linked immu- nosorbent assay (ELISA) for anti-T. gondii Immunoglobulin G (IgG) and Immunoglobulin M (IgM) antibodies. Positive
    T. gondii IgG and IgM were further tested for IgG avidity ELISA. All extracted deoxyribonucleic acids (DNAs) from whole blood samples were analyzed for the presence of the Toxoplasma B1 gene and the ITS1 region by polymerase chain reaction (PCR). The socio-demographic data of donors was assessed using a data collection form. Results: Out of 56 blood donors, 24 (42.86%) donors were IgG+/IgM-, and 2 (3.57%) donors were IgG+/IgM+ with one of them having a high avidity index indicating as past infection for more than 20 weeks and the other with a low avidity index indicating as recent infection within 20 weeks. None of the samples tested positive for the presence of the Toxoplasma B1 gene and the ITS1 region. A univariate analysis showed that only employment status was significantly associated with Toxoplasma seropositivity. Conclusion: The seroprevalence of toxoplasmosis among blood donors in Kelantan, Malaysia, was 46.43%. Nevertheless, direct detection by PCR showed that this parasite was absent in the blood. These results highlight that the blood donors in this study had previously been exposed to T. gondii infection. The parasite may still remain in certain tissues but does not freely circulate in the blood.
    MeSH terms: Animals; Antibodies, Protozoan; Blood Donors; Cross-Sectional Studies; Employment; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin G; Immunoglobulin M; Malaysia; Parasites; Toxoplasma; Toxoplasmosis; Prevalence; Seroepidemiologic Studies; Polymerase Chain Reaction
  20. Mohamed Paid Yusof, Idayu Badilla Idris, Nur Ashiqin Abd Rahman, Raudah Abd Rahman, Wan Rosmawati Wan Ismail
    MyJurnal
    Introduction: Measles outbreaks are endemic in Southeast Asia. A possible reason for such outbreaks is low vaccine coverage. In Malaysia, there is a lack of studies on measles outbreaks. The urban district of Petaling in Selangor, Peninsular Malaysia, reported a high number of outbreaks in 2014–2018. Thus, we analysed the trend of mea- sles outbreaks and identify the common characteristics of measles cases in Petaling District. Methods: This was a cross-sectional study using secondary data from the Petaling District Health Office online surveillance system. Data from 2014 until 2018 from the e-Measles and eWabak systems were extracted, and the trend and common character- istics of measles cases were analysed. Results: A total of 48 outbreaks involving 124 cases were reported during the period investigated. The outbreaks showed an increasing trend from 2.1% in 2014 to 37.5% in 2016, and decreased slightly from 29.2% in 2017 to 27.1% in 2018. The common characteristics were age 1 to
    MeSH terms: Asia, Southeastern; Cross-Sectional Studies; Disease Outbreaks; Malaysia; Measles; Measles Vaccine
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