• 1 Department of Otorhinolaryngology, Taiping Hospital, 34000 Taiping, Perak, Malaysia
  • 2 Department of Pathology, Taiping Hospital, 34000 Taiping, Perak, Malaysia
  • 3 Department of Otorhinolaryngology-Head & Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia, Health Campus 16150 Kota Bharu, Kelantan, Malaysia
Gulf J Oncolog, 2021 May;1(36):79-81.
PMID: 35017141


Malignant transformation of recurrent respiratory papillomatosis (RRP) is a rare entity occurring in only less than 5% of patients with RRP. The risk of transformation can arise even in the absence of risk factors such as smoking and radiation. We describe a patient with juvenile RRP diagnosed since childhood, who suffered malignant transformation into a squamous cell carcinoma after 29 years. Keywords: Recurrent respiratory papillomatosis; laryngeal neoplasms; squamous cell carcinoma; human papilloma-virus.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.