Affiliations 

  • 1 Division of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
  • 2 Division of Infectious Diseases and Tropical Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
  • 3 Department of Medical Microbiology, Postgraduate Institute of Medical Education & Research, Chandigarh, India
  • 4 Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
  • 5 Division of Haematology, Oncology and Bone Marrow Transplantation, University of Hong Kong, Pokfulam, Hong Kong
  • 6 School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei, Taiwan
  • 7 Department of Infectious Diseases, Singapore General Hospital Singapore 169608, Singapore
  • 8 Critical Care and Emergency Medicine, AMRI Hospitals, Kolkata, India
J Antimicrob Chemother, 2022 09 30;77(10):2579-2585.
PMID: 35904002 DOI: 10.1093/jac/dkac251

Abstract

Management of invasive mould infections (IMIs) is challenging in Asia, as awareness among medical practitioners can be low and resources are limited. Timely diagnosis and appropriate treatment of IMIs can mitigate the impact on morbidity and mortality, but diagnostic methods, as well as access to preferred antifungal medications, may vary throughout the region. Knowledge of local epidemiology and accurate diagnosis and identification of causal pathogens would facilitate optimal treatment but data in Asia are lacking. To address these unmet needs in the management of IMIs, this paper is a call for urgent action in the following areas: improving awareness of the threat of IMIs; providing education to frontline clinicians across a broad range of specialties on 'red flags' for suspicion of IMIs; prioritizing cost-effective rapid diagnostic testing; improving access to preferred antifungal medications; and closing the gaps in local epidemiological data on IMIs to inform local treatment guidelines.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.