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Expert consensus on the management of chronic lymphocytic leukaemia in Asia

Tse E 1 , Kwong YL 2 , Goh YT 3 , Bee PC 4 , Ng SC 5 , Tan D 6 Show all authors , Caguioa P 7 , Nghia H 8 , Dumagay T 9 , Norasetthada L 10 , Chuncharunee S 11 , Radhakrishnan V 12 , Bagal B 13 , Atmakusuma TD 14 , Mulansari NA 14

Affiliations 

  • 1 Division of Haematology, Medical Oncology and Haematopoietic Stem Cell Transplant, Department of Medicine, School of Clinical Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong, China. ewctse@hku.hk
  • 2 2.Division of Haematology, Medical Oncology and Haematopoietic Stem Cell Transplant, Department of Medicine, School of Clinical Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong, China
  • 3 Department of Haematology, Singapore General Hospital, Singapore, Singapore
  • 4 Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
  • 5 Subang Jaya Medical Centre (SJMC), Selangor, Malaysia
  • 6 Mount Elizabeth Novena Hospital, Singapore, Singapore
  • 7 Section of Haematology, St Luke's Medical Center, University of Santo Tomas Hospital, Manila, Philippines
  • 8 Blood Transfusion and Haematology Hospital (BTH), Ho Chi Minh, Vietnam
  • 9 Division of Haematology, Department of Medicine, Philippine General Hospital, Manila, Philippines
  • 10 Division of Haematology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
  • 11 Department of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
  • 12 Clinical Haematology Oncology and HCT, Tata Medical Centre, Kolkata, India
  • 13 Department of Medical Oncology, Tata Memorial Centre, Parel, India
  • 14 Haematology-Medical Oncology Division, Dr. Cipto Mangunkusumo National General Hospital/ Universitas Indonesia, Jakarta, Indonesia
Clin Exp Med, 2023 Oct;23(6):2895-2907.
PMID: 36795237 DOI: 10.1007/s10238-023-01007-2

Abstract

In recent years, considerable progress has been made in the standard treatment for chronic lymphocytic leukaemia (CLL) due to the availability of new potent drugs. However, the majority of data on CLL were derived from Western populations, with limited studies and guidelines on the management of CLL from an Asian population perspective. This consensus guideline aims to understand treatment challenges and suggest appropriate management approaches for CLL in the Asian population and other countries with a similar socio-economic profile. The following recommendations are based on a consensus by experts and an extensive literature review and contribute towards uniform patient care in Asia.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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