Affiliations 

  • 1 Institute for Clinical Research, National Institutes of Health, Ministry of Health, Selangor 40170, Malaysia
  • 2 Sector for Evidence-based Healthcare, National Institutes of Health, Ministry of Health, Selangor 40170, Malaysia
  • 3 Department of Ophthalmology, Shah Alam Hospital, Ministry of Health, Selangor 40000, Malaysia
  • 4 Department of Ophthalmology, Kuala Lumpur Hospital, Ministry of Health, Federal Territory 50586, Malaysia
  • 5 Department of Ophthalmology, Selayang Hospital, Ministry of Health, Selangor 61800, Malaysia
  • 6 Department of Ophthalmology, Tengku Ampuan Afzan Hospital, Ministry of Health, Pahang 25100, Malaysia
  • 7 Department of Ophthalmology, Sultanah Nur Zahirah Hospital, Ministry of Health, Kuala Terengganu 20400, Malaysia
  • 8 KPJ Selangor Specialist Hospital, Selangor 40300, Malaysia
  • 9 Sultan Abdul Aziz Shah Hospital, Selangor 43400, Malaysia
  • 10 Gleneagles Kuala Lumpur, Federal Territory 50450, Malaysia
  • 11 Department of Ophthalmology, Sungai Buloh Hospital, Ministry of Health, Selangor 47000, Malaysia
  • 12 Sunway Medical Centre, Selangor 47500, Malaysia
  • 13 Camden Medical Centre, Singapore 248649, Singapore
Int J Ophthalmol, 2023;16(5):712-720.
PMID: 37206185 DOI: 10.18240/ijo.2023.05.07

Abstract

AIM: To derive a Malaysia guideline and consensus as part of the Malaysia Retina Group's efforts for diagnosis, treatment, and best practices of diabetic macular edema (DME). The experts' panel suggests that the treatment algorithm to be divided into groups according to involvement the central macula. The purpose of DME therapy is to improve edema and achieve the best visual results with the least amount of treatment load.

METHODS: On two different occasions, a panel of 14 retinal specialists from Malaysia, together with an external expert, responded to a questionnaire on management of DME. A consensus was sought by voting after compiling, analyzing and discussion on first-phase replies on the round table discussion. A recommendation was deemed to have attained consensus when 12 out of the 14 panellists (85%) agreed with it.

RESULTS: The terms target response, adequate response, nonresponse, and inadequate response were developed when the DME patients' treatment responses were first characterized. The panelists reached agreement on a number of DME treatment-related issues, including the need to classify patients prior to treatment, first-line treatment options, the right time to switch between treatment modalities, and side effects associated with steroids. From this agreement, recommendations were derived and a treatment algorithm was created.

CONCLUSION: A detail and comprehensive treatment algorithm by Malaysia Retina Group for the Malaysian population provides guidance for treatment allocation of patients with DME.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.