Affiliations 

  • 1 Centre for Child & Adolescent Mental Health (CCAMH), University of Ibadan, Ibadan North, Nigeria
  • 2 Department of Aquaculture, Faculty of Fisheries and Marine, Universitas Airlangga, Jl. Mulyosari, Surabaya 60113, Indonesia
  • 3 Research Centre for Applied Microbiology, National Research and Innovation Agency (BRIN), Cibinong 16911, Indonesia
  • 4 Higher Institution Centre of Excellence (HiCoE), Institute of Tropical Aquaculture and Fisheries, Universiti Malaysia Terengganu, Kuala Terengganu 21030, Malaysia
  • 5 HeTA Centre of Excellence for Food Safety, School of Chemical Engineering, University of Birmingham, Birmingham B15 2SQ, UK
  • 6 Department of Food Quality and Safety and Veterinary Legislation, Faculty of Veterinary Medicine, Trakia University, 6000 Stara Zagora, Bulgaria
Antibiotics (Basel), 2023 Apr 28;12(5).
PMID: 37237733 DOI: 10.3390/antibiotics12050829

Abstract

The objective of this study was to examine the frequency and extent of antibiotic-resistant pathogens in seafood sold in Malaysia, using a systematic review and meta-analysis approach to analyze primary research studies. Four bibliographic databases were systematically searched for primary studies on occurrence. Meta-analysis using a random-effect model was used to understand the prevalence of antibiotic-resistant bacteria in retail seafood sold in Malaysia. A total of 1938 primary studies were initially identified, among which 13 met the inclusion criteria. In the included primary studies, a total of 2281 seafoods were analyzed for the presence of antibiotic-resistant seafood-borne pathogens. It was observed that 51% (1168/2281) of the seafood was contaminated with pathogens. Overall, the prevalence of antibiotic-resistant seafood-borne pathogens in retail seafood was 55.7% (95% CI: 0.46-0.65). Antibiotic-resistant Salmonella species had an overall prevalence of 59.9% (95% CI: 0.32-0.82) in fish, Vibrio species had an overall prevalence of 67.2% (95% CI: 0.22-0.94) in cephalopods, and MRSA had an overall prevalence of 70.9% (95% CI: 0.36-0.92) in mollusks. It could be concluded that there is a high prevalence of antibiotic-resistant seafood-borne pathogens in the retail seafood sold in Malaysia, which could be of public health importance. Therefore, there is a need for proactive steps to be taken by all stakeholders to reduce the widespread transmission of antibiotic-resistant pathogens from seafood to humans.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.