Affiliations 

  • 1 Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan
  • 2 Nanomaterials and Polymer Nanocomposites Laboratory, School of Engineering, University of British Columbia, Kelowna, BC V1V 1V7, Canada
  • 3 Biotechnology Research Center, Shiraz University of Medical Sciences, Shiraz 71439-14693, Iran
  • 4 Department of Chemical Engineering, School of Chemical and Petroleum Engineering, Shiraz 71557-13876, Iran
  • 5 Department of Pathology, Shiraz University of Medical Sciences, Shiraz 71439-14693, Iran
  • 6 Associate Professor of Endodontics Department of Endodontics, School of Dentistry Oral and Dental Disease Research Center Shiraz University of Medical Sciences, Shiraz 71956-15787, Iran
  • 7 Nanotechnology & Catalysis Research Centre (NANOCAT), University of Malaya (UM), Kuala Lumpur 50603, Malaysia
Materials (Basel), 2023 Jun 29;16(13).
PMID: 37444999 DOI: 10.3390/ma16134685

Abstract

Metal-organic frameworks (MOFs) have proven to be very effective carriers for drug delivery in various biological applications. In recent years, the development of hybrid nanostructures has made significant progress, including developing an innovative MOF-loaded nanocomposite with a highly porous structure and low toxicity that can be used to fabricate core-shell nanocomposites by combining complementary materials. This review study discusses using MOF materials in cancer treatment, imaging, and antibacterial effects, focusing on oral cancer cells. For patients with oral cancer, we offer a regular program for accurately designing and producing various anticancer and antibacterial agents to achieve maximum effectiveness and the lowest side effects. Also, we want to ensure that the anticancer agent works optimally and has as few side effects as possible before it is tested in vitro and in vivo. It is also essential that new anticancer drugs for cancer treatment are tested for efficacy and safety before they go into further research.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.