Affiliations 

  • 1 Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan
  • 2 Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
  • 3 Department of Mechanical Engineering, Center for Nanofibers and Nanotechnology, National University of Singapore, Singapore, Singapore
  • 4 Nanotechnology & Catalysis Research Centre, University of Malaya, Kuala Lumpur, Malaysia
  • 5 Department of Pharmaceutical Biotechnology, Faculty of Pharmacy and Pharmaceutical research Center, Shiraz University of Medical Science, Shiraz, Iran
Drug Metab Rev, 2020 05;52(2):299-318.
PMID: 32150480 DOI: 10.1080/03602532.2020.1734021

Abstract

Gold Nanostars (GNS) have attracted tremendous attention toward themselves owing to their multi-branched structure and unique properties. These state of the art metallic nanoparticles possess intrinsic features like remarkable optical properties and exceptional physiochemical activities. These star-shaped gold nanoparticles can predominantly be utilized in biosensing, photothermal therapy, imaging, surface-enhanced Raman spectroscopy and target drug delivery applications due to their low toxicity and extraordinary optical features. In the current review, recent approaches in the matter of GNS in case of diagnosis, bioimaging and biomedical applications were summarized and reported. In this regard, first an overview about the structure and general properties of GNS were reported and thence detailed information regarding the diagnostic, bioimaging, photothermal therapy, and drug delivery applications of such novel nanomaterials were presented in detail. Summarized information clearly highlighting the superior capability of GNS as potential multi-functional materials for biomedical applications.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.