Affiliations 

  • 1 Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei City 10617, Taiwan
  • 2 Nanomaterials and Polymer Nanocomposites Laboratory, School of Engineering, University of British Columbia, Kelowna, BC V1V 1V7, Canada
  • 3 Department of Medical Nanotechnology, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz 71345-1583, Iran
  • 4 Department of Materials Science and Engineering, School of Engineering, Shiraz University, Shiraz 71348-51154, Iran
  • 5 Department of Chemical Engineering, University of Mohaghegh Ardabili, Ardabil P.O. Box 179, Iran
  • 6 Department of Pathology, Shiraz University of Medical Sciences, Shiraz 71345-1583, Iran
  • 7 Nanotechnology & Catalysis Research Centre (NANOCAT), University of Malaya (UM), Kuala Lumpur 50603, Malaysia
  • 8 Biotechnology Research Center, Shiraz University of Medical Sciences, Shiraz 71345-1583, Iran
Int J Mol Sci, 2021 Jun 25;22(13).
PMID: 34202199 DOI: 10.3390/ijms22136850

Abstract

In this review, the unique properties of intrinsically conducting polymer (ICP) in biomedical engineering fields are summarized. Polythiophene and its valuable derivatives are known as potent materials that can broadly be applied in biosensors, DNA, and gene delivery applications. Moreover, this material plays a basic role in curing and promoting anti-HIV drugs. Some of the thiophene's derivatives were chosen for different experiments and investigations to study their behavior and effects while binding with different materials and establishing new compounds. Many methods were considered for electrode coating and the conversion of thiophene to different monomers to improve their functions and to use them for a new generation of novel medical usages. It is believed that polythiophenes and their derivatives can be used in the future as a substitute for many old-fashioned ways of creating chemical biosensors polymeric materials and also drugs with lower side effects yet having a more effective response. It can be noted that syncing biochemistry with biomedical engineering will lead to a new generation of science, especially one that involves high-efficiency polymers. Therefore, since polythiophene can be customized with many derivatives, some of the novel combinations are covered in this review.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.