Affiliations 

  • 1 Department of Mathematics and Computer Science, Echahid Cheikh Larbi Tebessi University, Tebessa, Algeria
  • 2 Department of Political Science, Bacha Khan University Charsadda, Charsadda, 24420, KPK, Pakistan
  • 3 Department of Civil Engineering, College of Engineering, Institute of Energy Infrastructure (IEI), Universiti Tenaga Nasional (UNITEN), Putrajaya Campus, Jalan IKRAM-UNITEN, 43000, Kajang, Selangor, Malaysia
  • 4 Department of Mathematics, College of Science, Qassim University, Buraydah, 51452, Saudi Arabia. s.boularas@qu.edu.sa
  • 5 Department of Mathematics, University of Swabi, Swabi, 23561, KPK, Pakistan
  • 6 Department of Mathematics, College of Science, Qassim University, Buraydah, 51452, Saudi Arabia
Sci Rep, 2024 Feb 06;14(1):3048.
PMID: 38321259 DOI: 10.1038/s41598-024-53696-8

Abstract

The infection of human papilloma virus (HPV) poses a global public health challenge, particularly in regions with limited access to health care and preventive measures, contributing to health disparities and increased disease burden. In this research work, we present a new model to explore the transmission dynamics of HPV infection, incorporating the impact of vaccination through the Atangana-Baleanu derivative. We establish the positivity and uniqueness of the solution for the proposed model HPV infection. The threshold parameter is determined through the next-generation matrix method, symbolized by [Formula: see text]. Moreover, we investigate the local asymptotic stability of the infection-free steady-state of the system. The existence of the solutions of the recommended model is determined through fixed-point theory. A numerical scheme is presented to visualize the dynamical behavior of the system with variation of input factors. We have shown the impact of input parameters on the dynamics of the system through numerical simulations. The findings of our investigation delineated the principal parameters exerting significant influence for the control and prevention of HPV infection.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.