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Challenges of implementing the Paediatric Surviving Sepsis Campaign International Guidelines 2020 in resource-limited settings: A real-world view beyond the academia

Wooldridge G 1 , O'Brien N 2 , Muttalib F 3 , Abbas Q 4 , Adabie Appiah J 5 , Baker T 6 Show all authors , Bansal A 7 , Basnet S 8 , Campos-Miño S 9 , de Souza DC 10 , Díaz F 11 , Dramowski A 12 , Fernández-Sarmiento J 13 , Fustiñana A 14 , González G 15 , Jabornisky R 16 , Jaramillo-Bustamante JC 17 , Yek Kee C 18 , Lang HJ 19 , Soares Lanziotti V , Kohn Loncarica G , Mohsenibod H , Ode B , Murthy S 20 , Andre-von Arnim AVS , Hansmann A 21 , González-Dambrauskas S

Affiliations 

  • 1 Royal Hospital for Children, Glasgow, United Kingdom
  • 2 The Ohio State University, Columbus, Ohio, USA
  • 3 Department of Paediatric Critical Care, BC Children's Hospital, Vancouver, Canada
  • 4 Department of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan
  • 5 Department of Child Health, Komfo Anokye Teaching Hospital, Kumasi, Ghana
  • 6 Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden
  • 7 Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India
  • 8 School of Medicine, Southern Illinois University, Springfield, Illinois, USA
  • 9 Department of Pediatrics, Hospital Metropolitano, Quito, Ecuador
  • 10 Universidade de São Paulo, Sao Paulo, Brazil
  • 11 Escuela de Postgrado, Universidad Finis Terrae, Santiago, Chile
  • 12 Department of Paediatrics and Child Health, Stellenbosch University, Cape Town, South Africa
  • 13 Graduate School, Universidad CES, Bogotá, Colombia
  • 14 Universidad de Buenos Aires, Buenos Aires, Argentina
  • 15 Hospital de Niños Ricardo Gutiérrez, Ciudad Autónoma de Buenos Aires, Argentina
  • 16 Department of Paediatric, National Northeasthern University, Argentina
  • 17 Department of Pediatrics, School of Medicine, Universidad de Antioquia, Medellin, Colombia
  • 18 Sarawak General Hospital, Malaysia
  • 19 Global Child Health Department, University Witten/Herdecke. Witten, Germany
  • 20 Department of Paediatric Critical Care, BC Children's Hospital. Vancouver, Canada
  • 21 National Pediatric Hospital. Phnom Penh, Cambodia
Andes Pediatr, 2021 Dec;92(6):954-962.
PMID: 35506809 DOI: 10.32641/andespediatr.v92i6.4030

Abstract

The Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-associated Organ Dysfunction in Children was released in 2020 and is intended for use in all global settings that care for children with sepsis. However, practitioners managing children with sep sis in resource-limited settings (RLS) face several challenges and disease patterns not experienced by those in resource-rich settings. Based upon our collective experience from RLS, we aimed to reflect on the difficulties of implementing the international guidelines. We believe there is an urgent need for more evidence from RLS on feasible, efficacious approaches to the management of sepsis and septic shock that could be included in future context-specific guidelines.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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