Harnessing the role of microneedles as sensors: current status and future perspectives

Ravindra Babu M 1 , Vishwas S 1 , Gulati M 2 , Dua K 3 , Kumar Singh S 4

Affiliations 

  • 1 School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, 144411 Punjab, India
  • 2 School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, 144411 Punjab, India; Faculty of Health, Australian Research Centre in Complementary and Integrative Medicine, University of Technology Sydney, Ultimo, NSW 2007, Australia
  • 3 Faculty of Health, Australian Research Centre in Complementary and Integrative Medicine, University of Technology Sydney, Ultimo, NSW 2007, Australia; Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo, NSW 2007, Australia
  • 4 School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, 144411 Punjab, India; Faculty of Health, Australian Research Centre in Complementary and Integrative Medicine, University of Technology Sydney, Ultimo, NSW 2007, Australia; School of Medical and Life Sciences, Sunway University, 47500 Sunway City, Malaysia. Electronic address: singhsachin23@gmail.com
Drug Discov Today, 2024 Jul;29(7):104030.
PMID: 38762087 DOI: 10.1016/j.drudis.2024.104030

Abstract

In recent years, microneedles (MNs) have been transformed to serve a wide range of applications in the biomedical field. Their role as sensors in wearable devices has provided an alternative to blood-based monitoring of health and diagnostic methods. Hence, they have become a topic of research interest for several scientists working in the biomedical field. These MNs as sensors offer the continuous monitoring of biomarkers like glucose, nucleic acids, proteins, polysaccharides and electrolyte ions, which can therefore screen for and diagnose disease conditions in humans. The present review focuses on types of MN sensors and their applications. Various clinical trials and bottlenecks of MN R&D are also discussed.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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