Affiliations 

  • 1 Department of Pathology, Microbiology and Forensic Medicine, School of Medicine, The University of Jordan, Amman 11942, Jordan
  • 2 Sheikh Jaber Al-Ahmad Al-Sabah Hospital, Ministry of Health, Kuwait City, Kuwait
  • 3 School of Medicine, The University of Jordan, Amman, Jordan
  • 4 Istishari Hospital, Amman, Jordan
  • 5 Jordan University Hospital, Amman, Jordan
  • 6 The Office of Infection Prevention and Control, Jordan University Hospital, Amman, Jordan
  • 7 Faculty of Pharmacy, Mansoura University, El Mansoura, Egypt
  • 8 Department of Clinical Pharmacy, Faculty of Pharmacy, Al-Baha University, Al-Baha, Saudi Arabia
  • 9 Restorative Department, Faculty of Dentistry, Zarqa University, Zarqa, Jordan
  • 10 Department of Pharmacy, Mediclinic Parkview Hospital, Mediclinic Middle East, Dubai, United Arab Emirates
  • 11 Department of Clinical Pharmacy and Therapeutics, Faculty of Pharmacy, Applied Science Private University, Amman, Jordan
Ther Adv Vaccines Immunother, 2025;13:25151355251324384.
PMID: 40027198 DOI: 10.1177/25151355251324384

Abstract

BACKGROUND: Respiratory syncytial virus (RSV) poses a significant respiratory health risk to senior citizens, contributing substantially to hospitalizations and mortality. With the recent approval of three RSV vaccines for the elderly, it is critical to understand the factors that can shape the RSV vaccination attitudes to inform public health strategies that can enhance uptake among this vulnerable population.

OBJECTIVES: This study aimed to investigate the potential factors that could influence the attitudes toward RSV vaccination among senior citizens in Arab countries.

DESIGN: A multinational cross-sectional study, adhering to STROBE guidelines, was conducted using a survey instrument previously validated through exploratory factor analysis to assess attitudes toward the newly approved RSV vaccine.

METHODS: A self-administered online survey was distributed conveniently among senior citizens mainly across five Arab countries. The survey collected data on demographics, vaccination history, and key constructs related to RSV vaccine attitude, including "Fear," "Information," "Accessibility," "Benefits," and "Conspiracy."

RESULTS: A total of 483 participants were included in the study, with the majority from five Arab countries: Jordan (n = 239, 49.5%), Kuwait (n = 74, 15.3%), Egypt (n = 68, 14.1%), Saudi Arabia (n = 51, 10.6%), and the UAE (n = 23, 4.8%), alongside participants from other Arab nations (n = 28, 5.8%). Among the respondents, 51.1% (n = 247) expressed acceptance of the RSV vaccine, 22.4% (n = 108) were hesitant, and 26.5% (n = 128) exhibited refusal. Multivariate analysis identified perceived benefits (β = 0.484, p 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.