A plain language summary of the results from the MAGNITUDE study assessing how effective and how safe niraparib and abiraterone acetate with prednisone is in patients with metastatic castration-resistant prostate cancer

Chi KN 1 , Rathkopf D 2 , Smith MR 3 , Efstathiou E 4 , Attard G 5 , Olmos D 6 Show all authors , Lee JY 7 , Small EJ 8 , Pereira de Santana Gomes AJ 9 , Roubaud G 10 , Saad M 11 , Zurawski B 12 , Sakalo V 13 , Mason GE 14 , Francis P 15 , Wang G 14 , Wu D 16 , Diorio B 17 , Lopez-Gitlitz A 16 , Sandhu S 18

Affiliations 

  • 1 aBC Cancer - Vancouver Center, University of British Columbia, Vancouver, BC, Canada
  • 2 bMemorial Sloan Kettering Cancer Center and Weill Cornell Medicine, New York, NY
  • 3 cMassachusetts General Hospital Cancer Center and Harvard Medical School, Boston, MA
  • 4 dHouston Methodist Cancer Center, Houston, TX
  • 5 eUniversity College London, London, UK
  • 6 fDepartment of Medical Oncology, Hospital Universitario 12 de Octubre, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Madrid, Spain
  • 7 gDepartment of Urology Cancer Center, Seoul St Mary's Hospital, The Catholic University of Korea, Seoul, South Korea
  • 8 hHelen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA
  • 9 iLiga Norte Riograndense Contra o Câncer, Natal, Brazil
  • 10 jDepartment of Medical Oncology, Institut Bergonié, Bordeaux, France
  • 11 kDepartment of Clinical Oncology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
  • 12 lDepartment of Outpatient Chemotherapy, Professor Franciszek Lukaszczyk Oncology Center, Bydgoszcz, Poland
  • 13 mKyiv City Clinical Oncology Center and Academician O.F. Vozianov Institute of Urology of the National Academy of Medical Sciences of Ukraine, Kyiv, Ukraine
  • 14 nJanssen Research & Development, LLC, Spring House, PA
  • 15 oJanssen Research & Development, LLC, Raritan, NJ
  • 16 pJanssen Research & Development, LLC, Los Angeles, CA
  • 17 qJanssen Research & Development, LLC, Titusville, NJ
  • 18 rPeter MacCallum Cancer Centre and the University of Melbourne, Melbourne, Australia
Future Oncol, 2025 Mar 30.
PMID: 40159790 DOI: 10.1080/14796694.2025.2470106

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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