• 1 Department of Surgery, Faculty of Medicine, Universiti Kebangsaan, Kuala Lampur, Malaysia
Ann Thorac Med, 2011 Jul;6(3):149-51.
PMID: 21760848 DOI: 10.4103/1817-1737.82451


The administration of intrapleural streptokinase (IPSK) is widely practiced in the management of loculated empyema thoracis. To our knowledge, there have been only 4 cases of hemorrhagic complications attributed to the administration of IPSK reported in the literature. In this article, we report a case of a 17-year-old girl who received IPSK and developed shock, anemia, coagulopathy and massive hemothorax. Our discussion focuses on the hemorrhagic complication of chest tube insertion and the role of IPSK in blood clot lysis and inhibition of local hemostasis.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.