Two new xanthones from Artocarpus obtusus

Hashim N 1 , Rahmani M , Sukari MA , Ali AM , Alitheen NB , Go R Show all authors , Ismail HB

Affiliations 

  • 1 Department of Chemistry, Universiti Putra Malaysia 43400 UPM, Selangor, Malaysia
J Asian Nat Prod Res, 2010 Feb;12(2):106-12.
PMID: 20390751 DOI: 10.1080/10286020903450411

Abstract

Two new xanthones, pyranocycloartobiloxanthone A (1) and dihydroartoindonesianin C (2), were isolated from the stem bark of Artocarpus obtusus Jarrett by chromatographic separation. Their structures were determined by using spectroscopic methods and comparison with known related compounds. Pyranocycloartobiloxanthone A (1) showed strong free radical scavenging activity by using DPPH assay as well as cytotoxicity towards K562, HL-60, and MCF7 cell lines.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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