Furoquinoline alkaloids from Melicope bonwickii (F.Muell.) T.Hartley

Komala I 1 , Rahmani M , Sukari MA , Mohd Ismail HB , Cheng Lian GE , Rahmat A

Affiliations 

  • 1 Department of Chemistry, Universiti Putra Malaysia, 43400 UPM, Serdang, Malaysia
Nat Prod Res, 2006 Apr;20(4):355-60.
PMID: 16644530

Abstract

Investigation on the leaves of Melicope bonwickii (F.Muell.) T.Hartley (Rutaceae) afforded a new 7-(2'-hydroxy-3'-chloroprenyloxy)-4-methoxyfuroquinoline (1) together with the known 7-(2',3'-epoxyprenyloxy)-4-methoxyfuroquinoline (2), evellerine (3) kokusaginine (4) and an amide aurantiamide acetate (5). Compounds 1 and 2 showed significant activity against cervical cell lines (Hela).

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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