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Evaluation of three commercial rapid tests for detecting antibodies to human immunodeficiency virus

Ng KP 1 , Saw TL 2 , Baki A 3 , Kamarudin R 4

Affiliations 

  • 1 K P Ng, MBBS. Viral Hepatitis & AIDS Laboratory, Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur
  • 2 T L Saw, MLT. Viral Hepatitis & AIDS Laboratory, Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur
  • 3 A Baki, MLT. Viral Hepatitis & AIDS Laboratory, Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur
  • 4 R Kamarudin, MLT. Viral Hepatitis & AIDS Laboratory, Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur
Med J Malaysia, 2003 Aug;58(3):454-60.
PMID: 14750391

Abstract

Determine HIV-1/2, Chembio HIV-1/2 STAT-PAK and PenTest are simple/rapid tests for the detection of antibodies to HIV-1 and HIV-2 in human whole blood, serum and plasma samples. The assay is one step and the result is read visually within 15 minutes. Using 92 known HIV-1 reactive sera and 108 known HIV-1 negative sera, the 3 HIV tests correctly identified all the known HIV-1 reactive and negative samples. The results indicated that Determine HIV-1/2, Chembio HIV-1/2 STAT-PAK and PenTest HIV are as sensitive and specific (100% concordance) as Microparticle Enzyme Immunoassay. The data indicated that these 3 HIV tests are effective testing systems for diagnosis of HIV infection in a situation when the conventional Enzyme Immunoassay is not suitable.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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