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A seroprevalence study of viral hepatitis E infection in human immunodeficiency virus type 1 infected subjects in Malaysia

Ng KP 1 , He J 2 , Saw TL 3 , Lyles CM 4

Affiliations 

  • 1 K P Ng, MBBS. K P Ng, MBBS. Viral Hepatitis & AIDS Laboratory, Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
  • 2 J He, MD. Viral Hepatitis & AIDS Laboratory, Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
  • 3 T L Saw, MLT. Viral Hepatitis & AIDS Laboratory, Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
  • 4 C M Lyles, PhD. Department of Epidemiology, Infectious Diseases Program, School of Hygiene and Public Health, The Johns Hopkins University, Baltimore, MD, USA 21205
Med J Malaysia, 2000 Mar;55(1):58-64.
PMID: 11072492 MyJurnal

Abstract

Hepatitis E virus (HEV) is a RNA virus transmitted enterically. A study of anti-HEV antibodies in 145 human immunodeficiency virus type 1 (HIV-1) infected subjects found that 14.4% of them were reactive to anti-HEV antibodies. Anti-HEV IgG and anti-HEV IgM was detected in 10.3% and 4.1% of the subjects respectively. Prevalence of anti-HEV (either IgG or IgM) was similar across all adult ages (p = 0.154), between the three ethnic groups (p = 0.378), and across risk groups (p = 0.120). The results showed that HEV infection in subjects recruited in this study was most likely transmitted via faecal-route.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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