• 1 The Kirby Institute, University of New South Wales, Sydney, Australia
  • 2 Center for Infectious Disease and Cancer Research, Kaohsiung Medical University, Kaohsiung City, Taiwan
  • 3 Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
  • 4 Division of Infectious Diseases, Brown University Alpert Medical School, RI, USA
  • 5 Faculty of Medicine Udayana University & Sanglah Hospital, Bali, Indonesia
  • 6 Department of Microbiology, Queen Mary Hospital, Faculty of Medicine, The University of Hong Kong, Hong Kong, China
  • 7 Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand
  • 8 Chiangrai Prachanukroh Hospital, Chiangrai, Thailand
  • 9 HIV-NAT/Thai Red Cross AIDS Research Centre, Bangkok, Thailand
  • 10 Hospital Sungai Buloh, Sungai Buloh, Malaysia
  • 11 University Malaya Medical Centre, Kuala Lumpur, Malaysia
  • 12 Research Institute for Tropical Medicine, Manila, Philippines
  • 13 TREAT Asia, amfAR-The Foundation for AIDS Research, Bangkok, Thailand
  • 14 Center for Infectious Disease and Cancer Research, Kaohsiung Medical University, Kaohsiung City, Taiwan; Department of Microbiology, Kaohsiung Medical University, Kaohsiung City, Taiwan. Electronic address:
Kaohsiung J. Med. Sci., 2015 Sep;31(9):445-53.
PMID: 26362956 DOI: 10.1016/j.kjms.2015.07.002


Human immunodeficiency virus (HIV)-1 epidemics in Asian countries are driven by varying exposures. The epidemiology of the regional pandemic has been changing with the spread of HIV-1 to lower-risk populations through sexual transmission. Common HIV-1 genotypes include subtype B and circulating recombinant form (CRF) 01_AE. Our objective was to use HIV-1 genotypic data to better quantify local epidemics. TASER-M is a multicenter prospective cohort of HIV-infected patients. Associations between HIV exposure, patient sex, country of sample origin and HIV-1 genotype were evaluated by multivariate logistic regression. Phylogenetic methods were used on genotypic data to investigate transmission relationships. A total of 1086 patients from Thailand, Hong Kong, Malaysia and the Philippines were included in analyses. Proportions of male patients within countries varied (Thailand: 55.6%, Hong Kong: 86.1%, Malaysia: 81.4%, Philippines: 93.8%; p 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.