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Trends of CD4 cell count levels at the initiation of antiretroviral therapy over time and factors associated with late initiation of antiretroviral therapy among Asian HIV-positive patients

Kiertiburanakul S 1 , Boettiger D 2 , Lee MP 3 , Omar SF 4 , Tanuma J 5 , Ng OT 6 Show all authors , Durier N 7 , Phanuphak P 8 , Ditangco R 9 , Chaiwarith R 10 , Kantipong P 11 , Lee CK 12 , Mustafa M 13 , Saphonn V 14 , Ratanasuwan W 15 , Merati TP 16 , Kumarasamy N 17 , Wong WW 18 , Zhang F 19 , Pham TT 20 , Pujari S 21 , Choi JY 22 , Yunihastuti E 23 , Sungkanuparph S 24 , TREAT Asia HIV Observational Databases (TAHOD) , TREAT Asia Studies to Evaluate Resistance (TASER)

Affiliations 

  • 1 Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; sasisopin.kie@mahidol.ac.th
  • 2 The Kirby Institute, University of New South Wales, Kensington, NSW, Australia
  • 3 Queen Elizabeth Hospital, Hong Kong, China SAR
  • 4 University of Malaya Medical Centre, Kuala Lumpur, Malaysia
  • 5 National Center for Global Health and Medicine, Toyama Shinjuku-ku, Tokyo, Japan
  • 6 Tan Tock Seng Hospital, Singapore
  • 7 TREAT Asia, amfAR - The Foundation for AIDS Research, Bangkok, Thailand
  • 8 HIV-NAT/Thai Red Cross AIDS Research Centre, Bangkok, Thailand
  • 9 Research Institute for Tropical Medicine, Manila, Philippines
  • 10 Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand
  • 11 Chiang Rai Prachanukroh Hospital, Chiang Rai, Thailand
  • 12 Hospital Sungai Buloh, Sungai Buloh, Malaysia
  • 13 Hospital Raja Perempuan Zainab II, Kota Bharu, Malaysia
  • 14 National Center for HIV/AIDS, Dermatology & STDs, Phnom Penh, Cambodia
  • 15 Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
  • 16 Faculty of Medicine, Udayana University & Sanglah Hospital, Bali, Indonesia
  • 17 YRG Centre for AIDS Research and Education, Chennai, India
  • 18 Taipei Veterans General Hospital and AIDS Prevention and Research Centre, National Yang-Ming University, Taipei, Taiwan
  • 19 Beijing Ditan Hospital, Beijing, China
  • 20 Bach Mai Hospital, Hanoi, Vietnam
  • 21 Institute of Infectious Diseases, Pune, India
  • 22 Division of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea
  • 23 Working Group on AIDS Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia
  • 24 Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
J Int AIDS Soc, 2014;17:18804.
PMID: 24598459 DOI: 10.7448/IAS.17.1.18804

Abstract

Although antiretroviral therapy (ART) has been rapidly scaled up in Asia, most HIV-positive patients in the region still present with late-stage HIV disease. We aimed to determine trends of pre-ART CD4 levels over time in Asian HIV-positive patients and to determine factors associated with late ART initiation.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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