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Scopulariopsis brevicaulis infection in a patient with acute myeloid leukemia

Ng KP 1 , Soo-Hoo TS 2 , Na SL 3 , Gan GG 4 , Sangkar JV 5 , Teh AKH 6

Affiliations 

  • 1 K P Ng, PhD. Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur
  • 2 T S Soo-Hoo, PhD. Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur
  • 3 S L Na, MLT. Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur
  • 4 G G Gan, MRCP. Department of Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur
  • 5 J V Sangkar, MRCP. Department of Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur
  • 6 A K H Teh, FRCP. Department of Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur
Med J Malaysia, 2003 Oct;58(4):608-12.
PMID: 15190640

Abstract

Scopulariopsis brevicaulis is a soil fungus normally associated with onychomycosis. It causes subcutaneous infection in immunocompromised patients and is rarely isolated from blood. A case of systemic Scopulariopsis brevicaulis infection was reported in a patient with acute myeloid leukemia. The patient developed persistent fever that did not respond to wide spectrum antibiotics and amphotericin B. Scopulariopsis brevicaulis was the only pathogen isolated from blood cultures. The fever subsided with itraconazole and there was no recurrence of fungal infection with prolonged maintenance of oral itraconazole.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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