High allele frequency of CYP2C9*3 (rs1057910) in a Negrito's subtribe population in Malaysia; Aboriginal people of Jahai

Rosdi RA 1 , Mohd Yusoff N 2 , Ismail R 3 , Soo Choon T 4 , Saleem M 2 , Musa N 5 Show all authors , Yusoff S 1

Affiliations 

  • 1 a Department of Paediatrics , School of Medical Sciences, Universiti Sains Malaysia , Health Campus, Kubang Kerian , Kelantan , Malaysia
  • 2 b Advanced Medical and Dental Institute, Universiti Sains Malaysia , Bertam, Kepala Batas , Pulau Pinang , Malaysia
  • 3 c Centre of Excellence for Research in AIDS (CERiA) , Level 17, Wisma RND, Jalan Pantai Baharu , Kuala Lumpur , Malaysia
  • 4 d Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia , Main Campus, Jalan Inovasi, Gelugor , Penang , Malaysia
  • 5 e Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia , Health Campus, Kubang Kerian , Kelantan , Malaysia , and
Ann Hum Biol, 2015 Sep 24.
PMID: 26402341

Abstract

CYP2C9 gene polymorphisms modulate inter-individual variations in the human body's responses to various endogenous and exogenous drug substrates. To date, little is known about the CYP2C9 gene polymorphisms among the aboriginal populations of the world, including those in Malaysia.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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