The management of a chemical inventory is necessary for safety purposes as well as for fulfilling regulatory compliance. In most academic laboratories, the management of chemicals is still being done manually, which is time-consuming. As a result, data are not updated and expired chemicals are unintentionally used. This research proposes that UHF Class 1 Gen 2 Radio Frequency Identification (RFID) technology be used in the development of a chemical inventory information system to ease chemical tracking as well as to shorten the inventory process time. An information system integrating RFID data and a web-based rule identification interface was developed. WAMP 2.2.17, PHP 5.3.5 and MySQL 5.5.8 were downloaded and a programming language was written to check the expiration date of the chemicals as well as to produce alert notification status. Wireless technology through GSM modem helped in producing alert messages using the Short Message System (SMS) of the nearly expired chemicals to the handphone of the person in charge in real time.