Affiliations 

  • 1 Department of Food Technology, University Putra Malaysia, 43400 Serdang, Selangor, Malaysia
  • 2 Department of Food Technology, University Putra Malaysia, 43400 Serdang, Selangor, Malaysia. Electronic address: olaniny56@gmail.com
  • 3 Department of Food Science, University Putra Malaysia, 43400 Serdang, Selangor, Malaysia
  • 4 Laboratory of Natural Products, Institute of Bioscience, University Putra Malaysia, 43400 Serdang, Selangor, Malaysia
Food Chem, 2017 Jun 01;224:365-371.
PMID: 28159281 DOI: 10.1016/j.foodchem.2016.12.075

Abstract

The solubility limitations of phenolic acids in many lipidic environments are now greatly improved by their enzymatic esterification in ionic liquids (ILs). Herein, four different ILs were tested for the esterification of dihydrocaffeic acid with hexanol and the best IL was selected for the synthesis of four other n-alkyl esters with different chain-lengths. The effect of alkyl chain length on the anti-oxidative properties of the resulted purified esters was investigated using β-carotene bleaching (BCB) and free radical scavenging method DPPH and compared with butylated hydroxytoluene (BHT) as reference compound. All four esters (methyl, hexyl, dodecyl and octadecyl dihydrocaffeates) exhibited relatively strong radical scavenging abilities. The scavenging activity of the test compounds was in the following order: methyl ester>hexyl ester⩾dodecyl ester>octadecyl ester>BHT while the order for the BCB anti-oxidative activity was; BHT>octadecyl ester>dodecyl ester>hexyl ester>methyl ester.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.