Genetic association of AKAP10 gene polymorphism with reduced risk of preterm birth

Langmia IM 1 , Apalasamy YD 1 , Suki SZ 1 , Omar SZ 2 , Mohamed Z 1

Affiliations 

  • 1 Pharmacogenomics Laboratory, Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
  • 2 Department of Obstetrics and Gynecology, University of Malaya, Kuala Lumpur, Malaysia
J Perinatol, 2015 Sep;35(9):700-4.
PMID: 26110499 DOI: 10.1038/jp.2015.68

Abstract

Preterm birth (PTB) is a multifactorial complication in which genetic and environmental factors contribute to the phenotype. The AKAP10 protein encoded by AKAP10 gene has a vital role in the maintenance of myometrial quiescence and pregnancy. This study aimed to investigate whether polymorphisms in the AKAP10 gene are associated with the risk of PTB.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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