Affiliations 

  • 1 Tianjin Key Laboratory of Pulp & Paper, Tianjin University of Science and Technology, Tianjin 300457, China ; State Key Laboratory of Pulp and Paper Engineering, South China University of Technology, Guangzhou 510640, China
  • 2 Tianjin Key Laboratory of Pulp & Paper, Tianjin University of Science and Technology, Tianjin 300457, China
  • 3 Water Research Unit, Faculty of Science and Natural Resources, University Malaysia Sabah 88400 Kota Kinabalu, Sabah, Malaysia
Open Med (Wars), 2015;10(1):473-478.
PMID: 28352739 DOI: 10.1515/med-2015-0081

Abstract

A series of 2-hydroxypropyltrimethyl ammonium chloride chitosan (HACC) was prepared by the reaction of chitosan with glycidyl trimethyl ammonium chloride. Structure of HACC was characterized by FT IR and 1H NMR spectroscopies, and it was proved that substitution reaction mainly occurs on the N element. Antimicrobial activities of HACC was examined against S. aureus, E. coli, and A. niger. Results indicatd that the inhibitory effects of HACC solutions were varied with HACC concentration, quaternization degrees, pH values, metal ions, and heat treatment. The antimicrobial properties of handsheets prepared from HACC were studied by the inhibition zone method, and the sheets had good antimicrobial properties against S. aureus and E. coli, and low inhibition rate against A. niger.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.