Displaying publications 1 - 20 of 78 in total

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  1. Luo H, Sun Y
    Sci Rep, 2024 May 10;14(1):10747.
    PMID: 38730009 DOI: 10.1038/s41598-024-60773-5
    This study investigates the impact of geopolitical risk (GPR) on consumption-based carbon (CCO2) emissions as well as the moderating role of environmental policy stringency (EPS) on the above relationship. Based on data collected from 27 countries from 1990 to 2020, the basic results from the sample of the study indicate that GPR accelerates CCO2 emissions. Quantile regression results reveal that the effect of GPR is more pronounced in countries with higher CCO2 emissions. Moreover, EPS weakens the escalating effect of GPR on CCO2 emissions. The robust test results validate the findings reported in the basic regression model. The heterogeneity test indicates that the impact of GPR on CCO2 emissions is greater in developing countries compared in developed countries. The study also proposes these policy implications based on the findings: (1) countries should ensure a stable political environment, establish a robust legal system and promote energy transition; and (2) the scope of environmental taxes should be expanded where different tax rates should be imposed in order to be useful in reducing CCO2 emissions.
  2. Sun Y, Chong WG
    Mater Horiz, 2023 Jul 03;10(7):2373-2397.
    PMID: 37144354 DOI: 10.1039/d3mh00045a
    The emergence of multifunctional wearable electronics over the past decades has triggered the exploration of flexible energy storage devices. As an important component of flexible batteries, novel electrodes with good flexibility, mechanical stability and high energy density are required to adapt to mechanical deformation while powering devices. Electrodes with sophisticated designed structures are key to achieving novel batteries and supercapacitors with extended lifetimes under long-term deformation exposures. Many different novel structures including serpentine, auxetic and biomimetic are explored to construct electrodes thanks to their excellent mechanical deformability in three dimensions. This paper considers the various design strategies established for fabricating flexible electrodes using novel structural modifications. The current state-of-the-art developments of novel structures made of two-dimensional (2D) planar and three-dimensional (3D) cellular, interconnected architectures for flexible energy storage with different functionalities, are discussed. The key tunable geometrical parameters of structures for achieving high performance are critically assessed, and the challenges and limitations of electrodes facing their practical application are revealed, to offer new insights into future prospects of this field.
  3. Yang F, Sun Y, Zhang Y, Wang T
    PMID: 34281094 DOI: 10.3390/ijerph18137157
    This study aims to analyze the development trend of the manufacturing industry transformation and upgrading in the Guangdong-Hong Kong-Macao Greater Bay Area (2008-2018). On the basis of synergetics, the order parameter method of factor analysis is used to study these factors. The results show that: (1) There are five slow variable factors, such as intelligent manufacturing industry, technological innovation, scale agglomeration, market demand, and fixed asset investment, which are important power sources of the transformation and upgrading of the manufacturing industry in Greater Bay Area. The development of these factors is relatively mature, and they cooperate with each other. (2) Similar to a fast variable of manufacturing development ecology, green development is an important coordinating factor in removing bottlenecks. Finally, suggestions for the development of the transformation and upgrading of the manufacturing industry are put forward.
  4. Luo H, Sun Y, Zhang L
    Sci Rep, 2024 Mar 28;14(1):7423.
    PMID: 38548882 DOI: 10.1038/s41598-024-58015-9
    This study investigates the impact of macroprudential policies on ecological footprint (EF) in the top 11 largest countries. This study uses country-level panel data from these countries, covering the period from 1992 to 2020. Findings indicate that macroprudential policies alleviates ecological footprint in the sample. Macroprudential policies primarily reduce the ecological footprint before medium quantile (50%) while the environmental benefits of the policies end in the later quantiles. Moreover, environmental policy stringency (EPS) amplifies the positive influence of macroprudential policies on environmental sustainability. Estimate results stay the same with basic regression results in the post-global financial crisis (GFC) period while the impact is positive in the pre-GFC period. Finally, other robust tests validate the findings reported in basic regression model. This study suggests that governments should customize various types of macroprudential policies while also considering environmental concerns. The achievement of a sustainable environment can be facilitated by the combined effects of macroprudential policies and EPS.
  5. Sun Y, Tang S, Dou Z, Wang T
    Heliyon, 2024 Aug 15;10(15):e35321.
    PMID: 39170233 DOI: 10.1016/j.heliyon.2024.e35321
    To help the manufacturing industry achieve high-quality development, it is urgent to identify the factors that affect the development of regional manufacturing. Compared to previous regression models, this article attempts to discover the nonlinear effects of different factors on regional manufacturing industry development (RMID) and their future impact trends. Based on the theory of new structural economics, we used order parameter analysis to examine the impact of environmental pollution and technology on RMID. The results indicate that: (1) The half of the cities promote industrial growth, but there are still three other situations: development slow down (3/21), a slight downward trend (5/21), and recession (2/21). (2) The two-thirds of cities adopt green development to promote industrial growth, while the development of other cities slows down (3/21), and some cities have a slight downward trend (4/21). The conclusion is as follows: (1) Through comparison, it is found that the impact of environment and technology on the RMID remains roughly synchronous, but currently the environmental promotion effect is greater. (2) We have found four technological development paths and can extend three green development models, effectively promoting RMID's green technology development. These suggestions will lay the foundation for promoting RMID.
  6. Sun Y, Sommer W, Sun Q, Cao X
    PMID: 40102329 DOI: 10.3758/s13414-025-03042-5
    Whether inverted faces are processed locally or involve holistic processing has been debated for several years. This study conducted two experiments to explore the extent of holistic processing of inverted faces. Experiment 1 adopted a face-congruency paradigm that orthogonally manipulated stimulus congruency and orientation. Experiment 2 employed the complete congruency paradigm to test whether misalignment effects of inverted faces are related to holistic processing. The results of both experiments consistently demonstrated that inverted faces are processed not only locally but also holistically, and that misalignment disrupts the holistic processing of inverted faces. Subsequently computational modeling showed that in the congruent condition, the contributions of holistic and local information in inverted face processing performance were 24% and 76%, respectively, whereas in the incongruent condition, they were 10% and 90%, respectively. Together, the present study reveals that also inverted faces are processed holistically, albeit to a lower degree than upright faces.
  7. Sun Y, Puspanathan P, Lim T, Lin D
    Cancer Biol Med, 2025 Mar 24.
    PMID: 40126094 DOI: 10.20892/j.issn.2095-3941.2024.0386
    Advances in the identification of molecular biomarkers and the development of targeted therapies have enhanced the prognosis of patients with advanced gastric cancer. Several established biomarkers have been widely integrated into routine clinical diagnostics of gastric cancer to guide personalized treatment. Human epidermal growth factor receptor 2 (HER2) was the first molecular biomarker to be used in gastric cancer with trastuzumab being the first approved targeted therapy for HER2-positive gastric cancer. Programmed death-ligand 1 positivity and microsatellite instability can guide the use of immunotherapies, such as pembrolizumab and nivolumab. More recently, zolbetuximab has been approved for patients with claudin 18.2-positive diseases in some countries. More targeted therapies, including savolitinib for MET-positive patients, are currently under clinical investigation. However, the clinical application of these diagnostic approaches could be hampered by many existing challenges, including invasive and costly sampling methods, variability in immunohistochemistry interpretation, high costs and long turnaround times for next-generation sequencing, the absence of standardized and clinically validated diagnostic cut-off values for some biomarkers, and tumor heterogeneity. Novel testing and analysis techniques, such as artificial intelligence-assisted image analysis and multiplex immunohistochemistry, and emerging therapeutic strategies, including combination therapies that integrate immune checkpoint inhibitors with targeted therapies, offer potential solutions to some of these challenges. This article reviews recent progress in gastric cancer testing, outlines current challenges, and explores future directions for biomarker testing and targeted therapy for gastric cancer.
  8. Dou Z, Sun Y, Wang T, Wan H, Fan S
    PMID: 34071373 DOI: 10.3390/ijerph18115800
    This study aims to analyze the development trend of the manufacturing industry of the Guangdong-Hong Kong-Macao Greater Bay Area (from 2008 to 2018) by constructing an evaluation system. On the basis of push-pull-mooring theory, we analyze these factors by using an entropy and cluster model. The results show the following: (1) Technological development had an obvious spatial distribution pattern of core regional radiation, while others did not. (2) Economic development was based on the city's existing industrial development system, while environmental development depended on governmental policies. (3) Compared with the environmental factor, the development trends of the economic and technological factors were more similar. Lastly, we provide four strategies for the development of the manufacturing industry in different cities.
  9. Gu H, Huang X, Chen Q, Sun Y, Tan CP
    J Fluoresc, 2020 May;30(3):687-694.
    PMID: 32378115 DOI: 10.1007/s10895-020-02546-7
    The influences of metal atoms on optimized geometry structures, relative energies, frontline molecular orbitals, and binding energies of metalloporphyrin-based fluorescent array sensor were systematically investigated by density functional theory (DFT) at B3LYP/LAN2DZ level. DFT calculated results reveal that the selected metal atoms in the center of the metalloporphyrin plane provide difference performances of metalloporphyrin-based fluorescent array sensor for the rapid determination of trimethylamine. The calculated binding energies have displayed in the following order at the most stable states: zinc porphyrin (ZnP) 
  10. Sun Y, Kamran HW, Razzaq A, Qadri FS, Suksatan W
    PMID: 34951096 DOI: 10.1002/ieam.4570
    The present study investigates the pathway toward sustainability in Malaysia while observing the effects of tourism and transportation services on economic growth and carbon emissions. The study applied the quantile autoregressive distributed lag approach during the period 1970-2018, along with Granger causality to explore dynamic and asymmetric causal associations between the proposed variables. The empirical outcomes indicate that the error correction parameters are significant across major quantiles, confirming the presence of steady-state equilibrium in the long run. The results demonstrate that tourism and transportation services contribute significantly to economic growth in the long run; however, their contribution varies at different quantiles. On the other hand, tourism and transportation services were found to mitigate carbon dioxide emissions mainly across higher emission quantiles, confirming the sustainability of the transportation and tourism sector in Malaysia. We also observe a bidirectional causality between model variables. These results suggest important policy implications. Integr Environ Assess Manag 2022;00:1-15. © 2021 SETAC.
  11. Liu P, Meng W, Wang S, Sun Y, Ashraf MA
    Open Med (Wars), 2015;10(1):473-478.
    PMID: 28352739 DOI: 10.1515/med-2015-0081
    A series of 2-hydroxypropyltrimethyl ammonium chloride chitosan (HACC) was prepared by the reaction of chitosan with glycidyl trimethyl ammonium chloride. Structure of HACC was characterized by FT IR and 1H NMR spectroscopies, and it was proved that substitution reaction mainly occurs on the N element. Antimicrobial activities of HACC was examined against S. aureus, E. coli, and A. niger. Results indicatd that the inhibitory effects of HACC solutions were varied with HACC concentration, quaternization degrees, pH values, metal ions, and heat treatment. The antimicrobial properties of handsheets prepared from HACC were studied by the inhibition zone method, and the sheets had good antimicrobial properties against S. aureus and E. coli, and low inhibition rate against A. niger.
  12. Fu W, He X, Sun Y, Wang C, Wang J, Dong Y
    Int J Dev Disabil, 2023;69(4):602-610.
    PMID: 37346253 DOI: 10.1080/20473869.2021.1985919
    The prosperity of inclusion of students with disabilities largely rest on the attitudes of mainstream teachers. Few studies explore the relationship among school climate, teachers' attitude on inclusion and teachers' efficacy in China. This study surveyed 266 general teachers in China to understand the role of teachers' efficacy on inclusive education between school climate and teachers' attitude. The results indicated that teachers hold positive attitudes towards inclusion on average, especially in the dimension of affection. Additionally, school climate, teachers' efficacy and teachers' attitude were significantly associated, and the mediating effect of teachers' efficacy between school climate and teachers' attitude were proved by mediation analyses. The findings suggested that creating more inclusive school climate and improving general teachers' knowledge and skills on inclusive education, especially the skills on collaboration with others, which could contribute to promote more positive attitude on inclusive education of general teachers.
  13. Zhou Y, Sun Y, Pan D, Xia Q, Zhou C
    J Sci Food Agric, 2023 Aug 30;103(11):5412-5421.
    PMID: 37038882 DOI: 10.1002/jsfa.12616
    BACKGROUND: Goose meat is rough and embedded with dense connective tissue, impairing protein solubility. Therefore, to improve the functional properties of goose myofibrillar protein (GMP), ultrasound was used to assist the phosphorylation of GMP.

    RESULTS: The fact that GMP attached covalently with the phosphate group of sodium tripolyphosphate (GMP-STP) was disclosed directly by Fourier transform infrared spectroscopy. Furthermore, ultrasound significantly improved the hydrophobicity and solubility of GMP-STP, which could be attributed to the conversion of α-helix to β-sheet, β-turns, and random coils by sonication. The spatial stabilization of the protein phosphorylation process was boosted by ultrasound, making the droplets more dispersed, and thus an improvement in the functional properties of GMP-STP was observed. Water-holding capacity, oil-binding capacity, and emulsifying and foaming properties were best at an ultrasound power of 400 W.

    CONCLUSION: Ultrasound-assisted phosphorylation has great potential to modulate the structure-function relationship of proteins. © 2023 Society of Chemical Industry.

  14. Li C, Lin S, Sun Y, Afshan S, Yaqoob T
    Resour Policy, 2022 Aug;77:102740.
    PMID: 35502418 DOI: 10.1016/j.resourpol.2022.102740
    Equity markets are prone to several external factors, especially in the lethal pandemic situation when the uncertainty regarding the spread of the COVID disrupts the daily financial and economic activities along with the sharp decline in the oil price causing severe devastations to people not just in terms of life and health but also in the form of finance. Therefore, to assess the presence of empirical association of the oil price, Covid-19, and news-based uncertainty with the equity market condition, the method of QARDL was applied in the current investigation. The results revealed that the relationship of OIL was found to be positive and significant across all of the quantiles of the Stock Price Index (SPI); news-based uncertainty was found to be negative and significant across all of the quantiles of SPI, whereas COVID19 has the negative and significant impact on SPI only in the bearish and stable market conditions. Based on the findings, balance government interventions are recommended, balancing the generation of economic activities and counter COVID spread.
  15. Sun Y, Li Y, Wang Y, Jiang D, Liu X
    Front Public Health, 2021;9:723084.
    PMID: 34604162 DOI: 10.3389/fpubh.2021.723084
    The Covid-19 outbreak has spread over the world, limiting population and trade, causing job losses, and forcing businesses to close. The study's goal is to look at Covid-19's pandemic and consumer survival as a mediator for the future of running a business when FMCG companies are doing well. The researchers employed a basic random sampling strategy to do a layered transverse evaluation of samples. EFA, CFA, and SEM are used to choose data collection techniques for participants at Covid-19. According to the data, Malaysia has resulted in job losses, business growth, and customer satisfaction retention, as well as an increase in unemployment, company closures, and a drop in overall GDP. The impact of the Covid-19 epidemic on survival, production, and GDP has been demonstrated. Incorporating technology into all aspects of a company's working practices reveals the necessity and capacity of the organization to adapt to new scenarios.
  16. Wu X, Zhang S, Lai J, Lu H, Sun Y, Guan W
    Exp Clin Transplant, 2020 12;18(7):823-831.
    PMID: 33349209 DOI: 10.6002/ect.2020.0108
    OBJECTIVES: Liver fibrosis is inevitable in the healing process of liver injury. Liver fibrosis will develop into liver cirrhosis unless the damaging factors are removed. This study investigated the potential therapy of Bama pig adipose-derived mesenchymal stem cells in a carbon tetrachloride-induced liver fibrosis Institute of Cancer Research strain mice model.

    MATERIALS AND METHODS: Adipose-derived mesenchymal stem cells were injected intravenously into the tails of mice of the Institute of Cancer Research strain that had been treated with carbon tetrachloride for 4 weeks. Survival rate, migration, and proliferation of adipose-derived mesenchymal stem cells in the liver were observed by histochemistry, fluorescent labeling, and serological detection.

    RESULTS: At 1, 2, and 3 weeks after adipose-derived mesenchymal stem cell injection, liver fibrosis was significantly ameliorated. The injected adipose-derived mesenchymal stem cells had hepatic differentiation potential in vivo, and the survival rate of adipose-derived mesenchymal stem cells declined over time.

    CONCLUSIONS: The findings in this study confirmed that adipose-derived mesenchymal stem cells derived from the Bama pig can be used in the treatment of liver fibrosis, and the grafted adipose-derived mesenchy-mal stem cells can migrate, survive, and differentiate into hepatic cells in vivo.

  17. Gou Z, Zheng H, He Z, Su Y, Chen S, Chen H, et al.
    Environ Pollut, 2023 Jan 15;317:120790.
    PMID: 36460190 DOI: 10.1016/j.envpol.2022.120790
    This study aims to investigate the positive effects of the combined use of Enterobacter cloacae and biochar on improving nitrogen (N) utilization. The greenhouse pots experimental results showed the synergy of biochar and E. cloacae increased soil total N content and plant N uptake by 33.54% and 15.1%, respectively. Soil nitrogenase (NIT) activity increased by 253.02%. Ammonia monooxygenase (AMO) and nitrate reductase (NR) activity associated with nitrification and denitrification decreased by 10.94% and 29.09%, respectively. The relative abundance of N fixing microorganisms like Burkholderia and Bradyrhizobium significantly increased. Sphingomonas and Ottowia, two bacteria involved in the nitrification and denitrification processes, were found to be in lower numbers. The E. cloacae's ability to fix N2 and promote the growth of plants allow the retention of N in soil and make more N available for plant development. Biochar served as a reservoir of N for plants by adsorbing N from the soil and providing a shelter for E. cloacae. Thus, biochar and E. cloacae form a synergy for the management of agricultural N and the mitigation of negative impacts of pollution caused by excessive use of N fertilizer.
  18. Sun Y, Jia X, Tan CP, Zhang B, Fu X, Huang Q
    Int J Biol Macromol, 2023 Apr 30;235:123886.
    PMID: 36870635 DOI: 10.1016/j.ijbiomac.2023.123886
    The formation of inclusion complexes (ICs) between V-type starch and flavors is traditionally conducted in an aqueous system. In this study, limonene was solid encapsulated into V6-starch under ambient pressure (AP) and high hydrostatic pressure (HHP). The maximum loading capacity reached 639.0 mg/g after HHP treatment, and the highest encapsulation efficiency was 79.9 %. X-ray Diffraction (XRD) results showed that the ordered structure of V6-starch was ameliorated with limonene, which avoided the reduction of the space between adjacent helices within V6-starch generated by HHP treatment. Notably, HHP treatment may force molecular permeation of limonene from amorphous regions into inter-crystalline amorphous regions and crystalline regions as the Small-angle X-ray scattering (SAXS) patterns indicated, leading to better controlled-release behavior. Thermogravimetry analysis (TGA) revealed that the solid encapsulation of V-type starch improved the thermal stability of limonene. Further, the release kinetics study showed that a complex prepared with a mass ratio of 2:1 under HHP treatment sustainably released limonene over 96 h and exhibited a preferable antimicrobial effect, which could extend the shelf life of strawberries.
  19. Sun Y, Zheng Y, Song L, Sun P, Zhao M, Zhou Y, et al.
    R Soc Open Sci, 2022 Jan;9(1):211632.
    PMID: 35242354 DOI: 10.1098/rsos.211632
    The measurement of the droplets' elasticity is vitally important in microfluidic and ink-jet printing. It refers to the ability of the droplet to restore its original shape and strong robustness. This study investigated a novel method to measure elasticity. The plate coated with super-hydrophobic layers pressed on a droplet and the elastic force was recorded by an electronic balance. Meanwhile, a mathematical model was constructed to calculate the changes of the droplet area under the force. The measurement showed that external work mainly converts into surface energy and the damping ratio increases from 0.068 to 0.261 with the increase of mass fraction from 0 to 80 wt%. It also indicates that the novel method can accurately and efficiently measure the elasticity of droplets.
  20. Han W, Chai X, Zaaboul F, Sun Y, Tan CP, Liu Y
    Food Chem, 2024 Mar 01;435:137584.
    PMID: 37774617 DOI: 10.1016/j.foodchem.2023.137584
    This study investigates the impact of various chain lengths of hydrophilic polyglycerol fatty acid esters (HPGEs), namely SWA-10D, M-7D and M-10D on protein interactions and their influence on the surface morphology and interfacial properties of low-fat aerated emulsions under different pressures conditions. M-7D and M-10D samples exhibited larger particle sizes, higher ζ-potential and rougher surface compared to SWA-10D sample at 1 % concentration of HPGEs. Consequently, M-7D and M-10D samples demonstrated lower values of G', G'', and higher values tan δ at the oil-water interface as pressure increased, thereby promoting the formation of less viscoelastic structures. M-7D sample, characterized by lower content of α-helix structures, resulted in an observable redshift in the NH and CO groups of the protein. Molecular docking analysis affirmed that M-7D sample exhibited a lower absolute binding energy value, indicating stronger interaction with the protein compared to other samples, ultimately contributing to the unstable interfacial membrane formed.
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