Affiliations 

  • 1 Department of Mechanical Engineering, University of Malaya, Kuala Lumpur 50603, Malaysia
  • 2 Mathematics Department, Faculty of Science, University of Tabuk, Saudi Arabia
  • 3 Department of Mechanical Engineering, Jain College of Engineering, Belagavi, 590014, India
  • 4 Department of Mechanical and Industrial Engineering, Mekelle University, Mekelle, Ethiopia
  • 5 Department of Mechanical and Industrial Engineering, Sultan Qaboos University, Al Khoud, Muscat, 123, Oman
Biomed Mater Eng, 2017;28(3):257-266.
PMID: 28527189 DOI: 10.3233/BME-171672

Abstract

The current study investigates the effect of multi stenosis on the hemodynamic parameters such as wall pressure, velocity and wall shear stress in the realistic left coronary artery. Patients CT scan image data of normal and diseased left coronary artery was chosen for the reconstruction of 3D coronary artery models. The diseased 3D model of left coronary artery shows a narrowing of more than 70% and 80% of area stenosis (AS) at the left main stem (LMS) and left circumflex (LCX) respectively. The results show that the decrease in pressure was found downstream to the stenosis as compared to the coronary artery without stenosis. The maximum pressure drop was noted across the 80% AS at the left circumflex branch. The recirculation zone was also observed immediate to the stenosis and highest wall shear stress was found across the 80% area stenosis. Our analysis provides an insight into the distribution of wall shear stress and pressure drop, thus improving our understanding on the hemodynamics in realistic coronary artery.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.