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To use the brief psychiatric rating scale to detect disorganized speech in schizophrenia: Findings from the REAP-AP study

Chon Park Y 1 , Kanba S 2 , Chong MY 3 , Tripathi A 4 , Kallivayalil RA 5 , Avasthi A 6 Show all authors , Grover S 6 , Chee KY 7 , J Tanra A 8 , Maramis MM 9 , Yang SY 10 , Sartorius N 11 , Tan CH 12 , Shinfuku N 13 , Park SC 14

Affiliations 

  • 1 Department of Neuropsychiatry, Hanyang University Guri Hospital, Guri, Republic of Korea
  • 2 Department of Neuropsychiatry, Graduate School of Medicine, Kyushu University, Fukuoka, Japan
  • 3 Chang Gung Memorial Hospital, Chang Gung University School of Medicine, Chiayi, Taiwan
  • 4 Department of Psychiatry, King George's Medical University, Chowk, Lucknow, India
  • 5 Pushpagiri Institute of Medical Sciences, Tiruvalla, Kerala, India
  • 6 Department of Psychiatry, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
  • 7 Tunku Abdul Rahman Institute of Neuroscience, Kuala Lumpur Hospital, Kuala Lumpur, Malaysia
  • 8 Wahidin Sudirohusodo University, Makassar, Sulawesi Selatan, Indonesia
  • 9 Department of Psychiatry, Dr. Soetomo Hospital, Faculty of Medicine, Airlangga University, Surabaya, Indonesia
  • 10 Department of Pharmacy, Songde Branch, Tapei City Hospital, Tapei, Taiwan
  • 11 Association of the Improvement of Mental Health Programs, Geneva, Switzerland
  • 12 Department of Pharmacology, National University Hospital, Singapore, Singapore
  • 13 Department of Social Welfare, School of Human Sciences, Seinan Gakuin University, Fukuoka, Japan
  • 14 Department of Psychiatry, Inje University College of Medicine and Haeundae Paik Hospital, Busan, Republic of Korea. Electronic address: cogito-ergo-sum@hanmail.net
Kaohsiung J. Med. Sci., 2018 Feb;34(2):113-119.
PMID: 29413227 DOI: 10.1016/j.kjms.2017.09.009

Abstract

Our study aimed to assess the psychometric validity of the conceptual disorganization item and other items of the Brief Psychiatric Rating Scale (BPRS) for detecting disorganized speech in patients with schizophrenia. We included 357 schizophrenia patients with disorganized speech and 1082 without disorganized speech from the survey centers in India, Indonesia, Japan, Malaysia, and Taiwan, using the data from the Research on Asian Psychotropic Patterns for Antipsychotics (REAP-AP) study. After adjusting the effects of confounding variables, a binary logistic regression model was fitted to identify BPRS items independently associated with disorganized speech. Receiver operating characteristic (ROC) curves were used to identify optimum cut-off scores and their sensitivities and specificities for detecting disorganized speech. After adjusting the effects of confounding variables, the fitted binary logistic regression model indicated that conceptual disorganization (P 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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