Affiliations 

  • 1 UTM-IRDA Digital Media Centre (MaGIC-X), Faculty of Computing, University Technology Malaysia, 81310 Skudai, Johor Bahru, Malaysia; Department of Higher Studies, University of Baghdad, Al-Jaderia, Baghdad, Iraq. Electronic address: m_altamimi75@yahoo.com
  • 2 UTM-IRDA Digital Media Centre (MaGIC-X), Faculty of Computing, University Technology Malaysia, 81310 Skudai, Johor Bahru, Malaysia
  • 3 Advanced Medical and Dental Institute, Universiti Sains Malaysia, Bertam, 13200 Kepala Batas Pulau Pinang, Malaysia
Magn Reson Imaging, 2015 Jul;33(6):787-803.
PMID: 25865822 DOI: 10.1016/j.mri.2015.03.008

Abstract

Resection of brain tumors is a tricky task in surgery due to its direct influence on the patients' survival rate. Determining the tumor resection extent for its complete information via-à-vis volume and dimensions in pre- and post-operative Magnetic Resonance Images (MRI) requires accurate estimation and comparison. The active contour segmentation technique is used to segment brain tumors on pre-operative MR images using self-developed software. Tumor volume is acquired from its contours via alpha shape theory. The graphical user interface is developed for rendering, visualizing and estimating the volume of a brain tumor. Internet Brain Segmentation Repository dataset (IBSR) is employed to analyze and determine the repeatability and reproducibility of tumor volume. Accuracy of the method is validated by comparing the estimated volume using the proposed method with that of gold-standard. Segmentation by active contour technique is found to be capable of detecting the brain tumor boundaries. Furthermore, the volume description and visualization enable an interactive examination of tumor tissue and its surrounding. Admirable features of our results demonstrate that alpha shape theory in comparison to other existing standard methods is superior for precise volumetric measurement of tumor.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.