Displaying publications 1 - 20 of 1927 in total

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  1. Fulltext A Standards Organization for Open and FAIR Neuroscience: the International Neuroinformatics Coordinating Facility
    Abrams MB, Bjaalie JG, Das S, Egan GF, Ghosh SS, Goscinski WJ, et al.
    Neuroinformatics, 2022 Jan;20(1):25-36.
    PMID: 33506383 DOI: 10.1007/s12021-020-09509-0
    There is great need for coordination around standards and best practices in neuroscience to support efforts to make neuroscience a data-centric discipline. Major brain initiatives launched around the world are poised to generate huge stores of neuroscience data. At the same time, neuroscience, like many domains in biomedicine, is confronting the issues of transparency, rigor, and reproducibility. Widely used, validated standards and best practices are key to addressing the challenges in both big and small data science, as they are essential for integrating diverse data and for developing a robust, effective, and sustainable infrastructure to support open and reproducible neuroscience. However, developing community standards and gaining their adoption is difficult. The current landscape is characterized both by a lack of robust, validated standards and a plethora of overlapping, underdeveloped, untested and underutilized standards and best practices. The International Neuroinformatics Coordinating Facility (INCF), an independent organization dedicated to promoting data sharing through the coordination of infrastructure and standards, has recently implemented a formal procedure for evaluating and endorsing community standards and best practices in support of the FAIR principles. By formally serving as a standards organization dedicated to open and FAIR neuroscience, INCF helps evaluate, promulgate, and coordinate standards and best practices across neuroscience. Here, we provide an overview of the process and discuss how neuroscience can benefit from having a dedicated standards body.
    Matched MeSH terms: Reproducibility of Results
  2. Validity and Reliability of Persian Version of the 12-Item Expectations Regarding Aging Survey
    Sharif Nia H, She L, Somasundram S, Khoshnavay Fomani F, Kaveh O, Hosseini L
    Int J Aging Hum Dev, 2023 Mar;96(2):248-262.
    PMID: 35266410 DOI: 10.1177/00914150221084650
    Objective:The present study was designed to assess the construct validity and reliability of the Persian version of the 12-item Expectations Regarding Aging (ERA) survey among the older adult Iranian population. Methods: The Persian version of this scale was developed using translation and revision in the current study. The construct validity was assessed through exploratory factor analysis (EFA) and confirmatory factor analysis (CFA). The reliability was assessed through internal consistency (Cronbach's alpha and McDonald's omega), composite reliability (CR), and maximal reliability (MaXR). The data compiled online was based on a sample of 400 older adults aged 65 years and older. Results: The Persian version includes 12 items loading onto three factors with 12 items explaining 46.633% of the total variance with excellent internal consistency and reliability. Conclusion: The Persian version of ERA is reliable and valid that can be used to assess the ERA concept among older adults.
    Matched MeSH terms: Reproducibility of Results*
  3. A systematic review of statistical methods used to test for reliability of medical instruments measuring continuous variables
    Zaki R, Bulgiba A, Nordin N, Azina Ismail N
    Iran J Basic Med Sci, 2013 Jun;16(6):803-7.
    PMID: 23997908
    Reliability measures precision or the extent to which test results can be replicated. This is the first ever systematic review to identify statistical methods used to measure reliability of equipment measuring continuous variables. This studyalso aims to highlight the inappropriate statistical method used in the reliability analysis and its implication in the medical practice.
    Matched MeSH terms: Reproducibility of Results
  4. Android application for type 2 diabetes mellitus
    Gayatri RW, Katmawanti S, Wardani HE, Low WY
    Enferm Clin, 2021 04;31 Suppl 2:S311-S315.
    PMID: 33849188 DOI: 10.1016/j.enfcli.2020.09.019
    The purpose of this study is to develop an interactive service for people with DM and design a product specifically for the Android operating system. This study employs a research and development (R&D) design. The research phase consisted of a situation analysis, data collection, product design, expert validation, product revision, product tryout, and final revision. The research instrument was a questionnaire. Data analysis involved descriptive quantitative in percentage form. The results of the validation from the Android application experts, which focused on display quality, technical concerns, audio, and video quality, were found at 93.75% (very acceptable). In addition, the results of the validity assessment from the material experts, including general health experts and nutritionists, reached 98.08% (very acceptable) and 86.54% (very feasible), respectively. Based on the results of expert validation, the application design is categorized as very acceptable for development as a DM interactive service product.
    Matched MeSH terms: Reproducibility of Results
  5. Fulltext Industry 5.0: Ethereum blockchain technology based DApp smart contract
    Rupa C, Midhunchakkaravarthy D, Hasan MK, Alhumyani H, Saeed RA
    Math Biosci Eng, 2021 08 23;18(5):7010-7027.
    PMID: 34517569 DOI: 10.3934/mbe.2021349
    The use of advanced technologies has increased drastically to maintain any sensitive records related to education, health, or finance. It helps to protect the data from unauthorized access by attackers. However, all the existing advanced technologies face some issues because of their uncertainties. These technologies have some lapses to provide privacy, attack-free, transparency, reliability, and flexibility. These characteristics are essential while managing any sensitive data like educational certificates or medical certificates. Hence, we designed an Industry 5.0 based blockchain application to manage medical certificates using Remix Ethereum blockchain in this paper. This application also employs a distributed application (DApp) that uses a test RPC-based Ethereum blockchain and user expert system as a knowledge agent. The main strength of this work is the maintenance of existing certificates over a blockchain with the creation of new certificates that use logistic Map encryption cipher on existing medical certificates while uploading into the blockchain. This application helps to quickly analyze the birth, death, and sick rate as per certain features like location and year.
    Matched MeSH terms: Reproducibility of Results
  6. Stochastic lead time demand estimation via Monte Carlo simulation technique in supply chain planning
    Mahdavi M, Mahdavi M
    Sains Malaysiana, 2014;43:629-636.
    This paper considers a Monte Carlo simulation based method for estimating cycle stocks (production lot-sizing stocks) in a typical batch production system, where a variety of products is scheduled for production at determined periods of time. Delivery time is defined as the maximum lead time and pre-assembly processing time of the product's raw materials in the method. The product's final assembly cycle and delivery time, which were obtained via the production schedule and supply chain simulation, respectively, were both considered to estimate the demand distribution of product based on total duration. Efficient random variates generators were applied to model the lead time of the supply chain's stages. In order to support the performance reliability of the proposed method, a real case study is conducted and numerically analyzed.
    Matched MeSH terms: Reproducibility of Results
  7. Fulltext Electrodiagnostic subtyping in Guillain-Barré syndrome: Use of criteria in practice based on a survey study in IGOS
    Arends S, Drenthen J, Van den Bergh PYK, Hadden RDM, Shahrizaila N, Dimachkie MM, et al.
    J Peripher Nerv Syst, 2022 Sep;27(3):197-205.
    PMID: 35700346 DOI: 10.1111/jns.12504
    Electrodiagnostic (EDx) studies are helpful in diagnosing and subtyping of Guillain-Barré syndrome (GBS). Published criteria for differentiation into GBS subtypes focus on cutoff values, but other items receive less attention, although they may influence EDx subtyping: (a) extensiveness of EDx testing, (b) nerve-specific considerations, (c) distal compound muscle action potential (CMAP)-amplitude requirements, (d) criteria for conduction block and temporal dispersion. The aims of this study were to investigate how these aspects were approached by neuromuscular EDx experts in practice and how this was done in previously published EDx criteria for GBS. A completed questionnaire was returned by 24 (of 49) members of the electrophysiology expertise group from the International GBS Outcome Study. Six published EDx criteria for GBS subtyping were compared regarding these aspects. The indicated minimal number of motor nerves to study varied among respondents and tended to be more extensive in equivocal than normal studies. Respondents varied considerably regarding usage of compression sites for subtyping (median/wrist, ulnar/elbow, peroneal/fibular head): 29% used all variables from all sites, 13% excluded all sites, and 58% used only some sites and/or variables. Thirty-eight percent of respondents required a minimal distal CMAP amplitude to classify distal motor latency as demyelinating, and 58% did for motor conduction velocity. For proximal/distal CMAP-amplitude ratio and F-wave latency, a requisite minimal CMAP amplitude was more often required (79%). Also, the various published criteria sets showed differences on all items. Practical use of EDx criteria for subtyping GBS vary extensively across respondents, potentially lowering the reproducibility of GBS subtyping.
    Matched MeSH terms: Reproducibility of Results
  8. Dried Blood Spots-A Platform for Therapeutic Drug Monitoring (TDM) and Drug/Disease Response Monitoring (DRM)
    Zailani NNB, Ho PC
    Eur J Drug Metab Pharmacokinet, 2023 Sep;48(5):467-494.
    PMID: 37495930 DOI: 10.1007/s13318-023-00846-4
    This review provides an overview on the current applications of dried blood spots (DBS) as matrices for therapeutic drug (TDM) and drug or disease response monitoring (DRM). Compared with conventional methods using plasma/serum, DBS offers several advantages, including minimally invasiveness, a small blood volume requirement, reduced biohazardous risk, and improved sample stability. Numerous assays utilising DBS for TDM have been reported in the literature over the past decade, covering a wide range of therapeutic drugs. Several factors can affect the accuracy and reliability of the DBS sampling method, including haematocrit (HCT), blood volume, sampling paper and chromatographic effects. It is crucial to evaluate the correlation between DBS concentrations and conventional plasma/serum concentrations, as the latter has traditionally been used for clinical decision. The feasibility of using DBS sampling method as an option for home-based TDM is also discussed. Furthermore, DBS has also been used as a matrix for monitoring the drug or disease responses (DRM) through various approaches such as genotyping, viral load measurement, assessment of inflammatory factors, and more recently, metabolic profiling. Although this research is still in the development stage, advancements in technology are expected to lead to the identification of surrogate biomarkers for drug treatment in DBS and a better understanding of the correlation between DBS drug levels and drug responses. This will make DBS a valuable matrix for TDM and DRM, facilitating the achievement of pharmacokinetic and pharmacodynamic correlations and enabling personalised therapy.
    Matched MeSH terms: Reproducibility of Results
  9. Fulltext Reliability and validity of the Malay version of the General Health Questionnaire (GHQ - 12) among urological patients
    Quek KF, Low WY, Razack AH, Chua CB, Loh CS
    Med J Malaysia, 2002 Jun;57(2):169-77.
    PMID: 24326647
    The aim of the study was to validate the Malay version of the General Quentionnaire (GHQ-12) in patients with psychiatric morbidity secondary to urological disorder. Validity and reliability were studied in patients with lower urinary tract symptoms (LUTS) and patients without LUTS. Internal consistency was excellent. A high degree of internal consistency was observed for each of the 12 items and total scores (Cronbach's alpha value = 0.50 and higher and 0.65 respectively. Test-retest correlation coefficient for the 12 items scores was highly significant. Intraclass correlation coefficient was high (ICC=0.47 and above). A significant level between baseline and post-treatment scores were observed across 3 items in the surgical group. The Mal-GHQ-12 is a suitable, reliable, valid and sensitive to clinical change in the Malaysian population.
    Matched MeSH terms: Reproducibility of Results*
  10. Fulltext Reliability and validity of Malay language version of International Physical Activity Questionnaire (IPAQ-M) among the Malaysian cohort participants
    Shamsuddin N, Poh BK, Syed Zakaria SZ, Noor MI, Jamal R
    Int J Public Health Res, 2015;5(2):643-653.
    MyJurnal
    Introduction: Validation of instruments is essential when assessing physical activity (PA). The aim of this study was to validate a Malay language version of the International Physical Activity Questionnaire (IPAQ-M) against Actical accelerometer and to determine its reliability and validity.
    Methods: A total of 90 Malay adults aged 35-65 years old participating in The Malaysian Cohort project were recruited for this study. The IPAQ-M is comprised of 12 items, covering vigorous, moderate, walking, sitting and sleeping activities, and was administered on two occasions (Day 1 and Day 9) by interviewing the participants. Participants wore the Actical accelerometer for seven consecutive days between the two interview sessions. Results Validity tests showed that time spent in moderate-vigorous physical activity (MVPA) (min/wk) from IPAQ-M was significantly correlated with MVPA from accelerometer (rho=0.32, p<0.01). Time spent in vigorous activity (rho=0.44) and total activity (rho=0.36) from IPAQ-M were significantly correlated (p<0.01) with that measured by accelerometer, but no correlation was observed for sedentary behaviour. Reliability tests revealed significant correlations between the two interview sessions for all intensities of PA (rho=0.55 to 0.71, p<0.01). Bland-Altman plots showed that time spent in MVPA for IPAQ-M was significantly different from that measured by accelerometer (mean difference: 98.02 min/wk; 95% limits of agreement: -785.33 to 1317.83 min/wk; p<0.01). When classifying people into meeting PA recommendation, the agreement between the two instruments was fair (κ=0.22).
    Conclusions The IPAQ-M has acceptable validity for MVPA, vigorous and total physical activity, and was reliable for assessing the physical activity of Malay adults.
    Keywords Health care workers - Knowledge - Practice - Universal precaution - Health center.
    Study name: The Malaysian Cohort (TMC) Project
    Matched MeSH terms: Reproducibility of Results*
  11. Fulltext Design of miniaturized double-negative material for specific absorption rate reduction in human head
    Faruque MR, Islam MT
    PLoS One, 2014;9(10):e109947.
    PMID: 25350398 DOI: 10.1371/journal.pone.0109947
    In this study, a double-negative triangular metamaterial (TMM) structure, which exhibits a resounding electric response at microwave frequency, was developed by etching two concentric triangular rings of conducting materials. A finite-difference time-domain method in conjunction with the lossy-Drude model was used in this study. Simulations were performed using the CST Microwave Studio. The specific absorption rate (SAR) reduction technique is discussed, and the effects of the position of attachment, the distance, and the size of the metamaterials on the SAR reduction are explored. The performance of the double-negative TMMs in cellular phones was also measured in the cheek and the tilted positions using the COMOSAR system. The TMMs achieved a 52.28% reduction for the 10 g SAR. These results provide a guideline to determine the triangular design of metamaterials with the maximum SAR reducing effect for a mobile phone.
    Matched MeSH terms: Reproducibility of Results
  12. Fulltext Reliable geographical forwarding in cognitive radio sensor networks using virtual clusters
    Zubair S, Fisal N
    Sensors (Basel), 2014;14(5):8996-9026.
    PMID: 24854362 DOI: 10.3390/s140508996
    The need for implementing reliable data transfer in resource-constrained cognitive radio ad hoc networks is still an open issue in the research community. Although geographical forwarding schemes are characterized by their low overhead and efficiency in reliable data transfer in traditional wireless sensor network, this potential is still yet to be utilized for viable routing options in resource-constrained cognitive radio ad hoc networks in the presence of lossy links. In this paper, a novel geographical forwarding technique that does not restrict the choice of the next hop to the nodes in the selected route is presented. This is achieved by the creation of virtual clusters based on spectrum correlation from which the next hop choice is made based on link quality. The design maximizes the use of idle listening and receiver contention prioritization for energy efficiency, the avoidance of routing hot spots and stability. The validation result, which closely follows the simulation result, shows that the developed scheme can make more advancement to the sink as against the usual decisions of relevant ad hoc on-demand distance vector route select operations, while ensuring channel quality. Further simulation results have shown the enhanced reliability, lower latency and energy efficiency of the presented scheme.
    Matched MeSH terms: Reproducibility of Results
  13. Fulltext Development, test-retest reliability and validity of the Pharmacy Value-Added Services Questionnaire (PVASQ)
    Tan CL, Hassali MA, Saleem F, Shafie AA, Aljadhey H, Gan VB
    Pharm Pract (Granada), 2015 Apr-Jun;13(3):598.
    PMID: 26445622 DOI: 10.18549/PharmPract.2015.03.598
    (i) To develop the Pharmacy Value-Added Services Questionnaire (PVASQ) using emerging themes generated from interviews. (ii) To establish reliability and validity of questionnaire instrument.
    Matched MeSH terms: Reproducibility of Results
  14. Artificial olfactory system with fault-tolerant sensor array
    Lotfivand N, Abdolzadeh V, Hamidon MN
    ISA Trans, 2016 Jul;63:425-435.
    PMID: 27038885 DOI: 10.1016/j.isatra.2016.03.012
    Numerous applications of artificial olfaction resulting from research in many branches of sciences have caused considerable interest in the enhancement of these systems. In this paper, we offer an architecture which is suitable for critical applications, such as medical diagnosis, where reliability and precision are deemed important. The proposed architecture is able to tolerate failures in the sensors of the array. In this study, the discriminating ability of the proposed architecture in detecting complex odors, as well as the performance of the proposed architecture in encountering sensor failure, were investigated and compared with the generic architecture. The results demonstrated that by applying the proposed architecture in the artificial olfactory system, the performance of system in the healthy mode was identical to the classic structure. However, in the faulty situation, the proposed architecture implied high identification ability of odor samples, while the generic architecture showed very poor performance in the same situation. Based on the results, it was possible to achieve high odor identification through the developed artificial olfactory system using the proposed architecture.
    Matched MeSH terms: Reproducibility of Results
  15. The use of BLRP model for disaggregating daily rainfall affected by monsoon in Peninsular Malaysia
    Zulkifli Yusop, Harisaweni, Fadhilah Yusof
    Sains Malaysiana, 2016;45:87-97.
    Rainfall intensity is the main input variable in various hydrological analysis and modeling. Unfortunately, the quality of rainfall data is often poor and reliable data records are available at coarse intervals such as yearly, monthly and daily. Short interval rainfall records are scarce because of high cost and low reliability of the measurement and the monitoring systems. One way to solve this problem is by disaggregating the coarse intervals to generate the short one using the stochastic method. This paper describes the use of the Bartlett Lewis Rectangular Pulse (BLRP) model. The method was used to disaggregate 10 years of daily data for generating hourly data from 5 rainfall stations in Kelantan as representative area affected by monsoon period and 5 rainfall stations in Damansara affected by inter-monsoon period. The models were evaluated on their ability to reproduce standard and extreme rainfall model statistics derived from the historical record over disaggregation simulation results. The disaggregation of daily to hourly rainfall produced monthly and daily means and variances that closely match the historical records. However, for the disaggregation of daily to hourly rainfall, the standard deviation values are lower than the historical ones. Despite the marked differences in the standard deviation, both data series exhibit similar patterns and the model adequately preserve the trends of all the properties used in evaluating its performances.
    Matched MeSH terms: Reproducibility of Results
  16. Fulltext Maintenance and physical asset management issues in project commissioning
    Ahmad Fuad Ab Ghani, Azrin Ahmad, Nor Salim Muhammad, Reduan Mat Dan, Rustamreen Jenal
    Malaysian Journal of Applied Sciences, 2018;2(2):10-28.
    MyJurnal
    This study describes the review on maintenance related issues during design and construction stage
    within construction industry. The paper highlights the causes and errors made during design and
    construction stage and their impact during the operation/production/occupancy stage as well as the
    maintenance costs associated with it. The study identifies the mistakes in the working processes within
    design and construction stage leading to the errors that affect the durability, performance, reliability,
    maintainability, availability and safety of the systems. The paper presents a comprehensive review of
    the published literatures, journals, technical papers in the related areas in the construction field. The
    review highlights the new approaches and decision framework which link the designers and
    construction personnel that could reduce the errors and defects in construction which then lead to
    maintenance issues and asset management. The factors of accessibility, materials, design and
    documentation standardization have been discussed thoroughly for better understanding in improving
    maintenance and physical asset management in project commissioning.
    Matched MeSH terms: Reproducibility of Results
  17. Fulltext Application of artificial neural network for automatic contingency analysis in power security assessment
    Ismail Musirin, Titik Khawa Abdul Rahman
    Scientific Research Journal, 2006;3(1):11-25.
    MyJurnal
    Several incidents that occurred around the world involving power failure
    caused by unscheduled line outages were identified as one of the main
    contributors to power failure and cascading blackout in electric power
    environment. With the advancement of computer technologies, artificial
    intelligence (AI) has been widely accepted as one method that can be applied
    to predict the occurrence of unscheduled disturbance. This paper presents
    the development of automatic contingency analysis and ranking algorithm
    for the application in the Artificial Neural Network (ANN). The ANN is
    developed in order to predict the post-outage severity index from a set of preoutage
    data set. Data were generated using the newly developed automatic
    contingency analysis and ranking (ACAR) algorithm. Tests were conducted
    on the 24-bus IEEE Reliability Test Systems. Results showed that the developed
    technique is feasible to be implemented practically and an agreement was
    achieved in the results obtained from the tests. The developed ACAR can be
    utilised for further testing and implementation in other IEEE RTS test systems
    particularly in the system, which required fast computation time. On the other
    hand, the developed ANN can be used for predicting the post-outage severity
    index and hence system stability can be evaluated.
    Matched MeSH terms: Reproducibility of Results
  18. CMF-iteMS: An automatic threshold selection for detection of copy-move forgery
    Abd Warif NB, Idris MYI, Abdul Wahab AW, Salleh R, Ismail A
    Forensic Sci Int, 2019 Feb;295:83-99.
    PMID: 30576953 DOI: 10.1016/j.forsciint.2018.12.004
    Taking into consideration that the prior CMF detection methods rely on several fixed threshold values in the filtering process, we propose an efficient CMF detection method with an automatic threshold selection, named as CMF-iteMS. The CMF-iteMS recommends a PatchMatch-based CMF detection method that adapts Fourier-Mellin Transform (FMT) as the feature extraction technique while a new automatic threshold selection based on iterative means of regions size (iteMS) procedure is introduced to have flexibility in changing the threshold value for various characteristics (quality, sizes, and attacks) in each input image. To ensure the reliability of the proposed CMF-iteMS, the method is compared with four state-of-the-art CMF detection methods based on Scale Invariant Feature Transform (SIFT), patch matching, multi-scale analysis and symmetry techniques using three available datasets that cover the variety of characteristics in CMF images. The results show that the F-score of the CMF-iteMS outperformed existing CMF detection methods by exceeding an average of 90% F-score values for image-level evaluation and 82% of F-score value for pixel-level evaluation for all datasets in original size. As special attention is given to the image resizing attack, the method is able to maintain the highest performance even if the images in the datasets are resized to 0.25 parameter.
    Matched MeSH terms: Reproducibility of Results
  19. Cross-cultural adaptation and validation of the Malay health assessment questionnaire for use in rheumatoid arthritis
    Hussein H, Mustafa R, Quek KF, Hassanudin NS, Shahid S
    Int J Rheum Dis, 2008;11(3):237-240.
    DOI: 10.1111/j.1756-185X.2008.00384.x
    Objective: To validate the Malay version of the Health Assessment Questionnaire (Malay-HAQ) for use in Malay-speaking rheumatoid arthritis (RA) patients in the Malaysian setting. The HAQ - Disability Index has been validated in several languages, but not in Malay.Methods: The original HAQ was modified and translated into Malay by two translators, one of whom was aware of the objectives of the Questionnaire and the other as a lay translator. Two sets of Malay-HAQ were distributed to RA patients during their routine follow-up visits; one set to be completed immediately and another set to be completed 2 weeks later. A total of 61 patients completed the two sets of Malay-HAQ. The data collected was analysed using SPSS V. 11.0. Reliability of the data was evaluated using the test-retest method and internal consistency was assessed by Cronbach's alpha.Results: The study showed that the Malay-HAQ is feasible and reliable. The Spearman's correlation coefficient ranged from 0.65 to 0.82, while the internal consistency was 0.88-0.92.Conclusion: The Malay-HAQ is a sensitive, reliable and valid instrument for the measurement of functional status in RA patients in a Malay setting. © 2008 Asia Pacific League of Associations for Rheumatology.
    Matched MeSH terms: Reproducibility of Results
  20. Fulltext Validation and reliability of a prototype orthodontic bracket debonding device equipped with force-sensitive resistor (FSR): a novel method of measuring orthodontic bracket debonding force in vivo
    Ahmed T, Rahman NA, Alam MK
    Prog Orthod, 2019 Jul 08;20(1):26.
    PMID: 31281954 DOI: 10.1186/s40510-019-0277-x
    BACKGROUND: To introduce an orthodontic bracket debonding device capable of measuring debonding force clinically by a novel sensor mechanism MATERIALS AND METHOD: A prototype orthodontic debonding device was constructed utilizing a lift-off debonding instrument (LODI) and force-sensitive resistor (FSR). For data interpretation, the force sensor was equipped with a microcontroller and C++ programming software running on a computer. Ninety-nine (99) 0.022-in. conventional metallic brackets were bonded to premolar teeth in vitro by a single clinician applying the same adhesive and bonding technique. For validation, the mean debonding force measured by the prototype debonding device (n = 30) and the universal testing machine (n = 30) was compared. Both intra- and inter-examiner reliability tests were done by holding and operating the device in a standardized manner. Following debonding by the prototype device, the bracket failure pattern was evaluated (n = 30) by adhesive remnant index (ARI) under the stereomicroscope at × 30 magnification. Statistical analysis included independent samples t test for validation and intraclass correlation coefficient (ICC) with a 95% confidence interval for both intra- and inter-examiner reliability.

    RESULTS: Mean orthodontic bracket debonding force measured by the prototype device (9.36 ± 1.65 N) and the universal testing machine (10.43 ± 2.71 N) was not significantly different (p 

    Matched MeSH terms: Reproducibility of Results
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