Artificial tissue sensitized with encapsulated methylene blue encapsulated by silica nanoparticles in photodynamic therapy

Makhadmeh GN 1 , Abdul Aziz A 2 , Abdul Razak K 3

Affiliations 

  • 1 a School of Physics, Universiti Sains Malaysia, USM , Penang , Malaysia
  • 2 c NanoBiotechnology Research and Innovation (NanoBRI), Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, USM , Penang , Malaysia
  • 3 b School of Materials and Mineral Resources Engineering, Universiti Sains Malaysia , Nibong Tebal, Penang , Malaysia
Artif Cells Nanomed Biotechnol, 2016 Aug;44(5):1285-9.
PMID: 25811998 DOI: 10.3109/21691401.2015.1024843

Abstract

The synthesis of methylene blue (MB) encapsulated in silica nanoparticles (SiNPs) as an application for photodynamic therapy is reported in this study. Semi-rigid tissues with optical properties similar to that of human tissues were used as sample materials to determine the applicability of MB encapsulated in SiNPs.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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