A new mechanism of thermal sensitivity for rapid drug release and low systemic toxicity in hyperthermia and thermal ablation temperature ranges

Dabbagh A 1 , Abdullah BJ , Abu Kasim NH , Abdullah H , Hamdi M

Affiliations 

  • 1 Department of Biomedical Imaging, Faculty of Medicine, University of Malaya , Kuala Lumpur , Malaysia
Int J Hyperthermia, 2015 Jun;31(4):375-85.
PMID: 25716769 DOI: 10.3109/02656736.2015.1006268

Abstract

The aim of this paper was to introduce a new mechanism of thermal sensitivity in nanocarriers that results in a relatively low drug release at physiological temperature and rapid release of the encapsulated drug at hyperthermia and thermal ablation temperature range (40-60 °C).

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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