Low-melting-point polymeric nanoshells for thermal-triggered drug release under hyperthermia condition

Dabbagh A 1 , Mahmoodian R 2 , Abdullah BJ 1 , Abdullah H 3 , Hamdi M 2 , Abu Kasim NH 3

Affiliations 

  • 1 a Department of Biomedical Imaging , Faculty of Medicine, University of Malaya , Kuala Lumpur
  • 2 c Department of Mechanical Engineering , Faculty of Engineering, University of Malaya , Kuala Lumpur
  • 3 d Department of Restorative Dentistry , Faculty of Dentistry, University of Malaya , Kuala Lumpur , and
Int J Hyperthermia, 2015;31(8):920-9.
PMID: 26670340 DOI: 10.3109/02656736.2015.1094147

Abstract

The aim of this paper was to synthesise core-shell nanostructures comprised of mesoporous silica core and a low melting-point polyethylene glycol (PEG) nanoshell with a sharp gel-liquid phase transition for rapid drug release at hyperthermia temperature range.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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