Affiliations 

  • 1 National University Health System, Department of Medicine, Singapore. wkwong100@yahoo.com
  • 2 National University Health System, Department of Pathology, Singapore
  • 3 National University Health System, Department of Medicine, Singapore
Med J Malaysia, 2019 02;74(1):97-98.
PMID: 30846674

Abstract

Thymoma is a rare mediastinal tumour that can be accompanied by different paraneoplastic syndromes. Here we report a case of Type A thymoma associated with relapsing minimal change disease (MCD). This case highlights: (1) The need to balance rapid prednisolone weaning against risk for relapse in an elderly patient at risk for steroid-induced complications. (2) The addition of calcineurin inhibitor in relapsed thymoma-related MCD, to achieve steroid sparing effects. Resection of the offending tumour and prompt immunosuppressive therapy are critical in getting best renal and overall outcomes in this rare entity.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.