This study was conducted to compare the treatment outcome using patching in patients with strabismic amblyopia and refractive amblyopia. The treatment outcome was measured by visual acuity and refractive error. A total of 28 patients participated in this study. One group comprised of strabismic amblyopes who had either congenital esotropia or intermittent exotropia and spherical equivalent refractive error of less than -3.00 DS. Another group of patients were purely refractive amblyopes. Patients were first corrected with the best correction for a month. When the VA in the amblyopic eye did not improve over the month, then patching treatment was started. Patching was done daily for 2 h together with near activity. The treatment was carried out for 4 months, with the patients reviewed once every month. The results of the study revealed that VA improved by 17 alphabets or 3 lines after patching treatment for patients with strabismic amblyopia. In the refractive amblyopia group, the VA only improved by 8 alphabets or 1 line 3 alphabets. The mean spherical equivalent refractive error changed by less than -0.50DS and therefore was clinically not significant in both groups. This present study showed that patching treatment was better at improving the VA of patients with strabismic amblyopia.