Spirulina platensis based biorefinery for the production of value-added products for food and pharmaceutical applications

Chia SR 1 , Chew KW 1 , Show PL 2 , Xia A 3 , Ho SH 4 , Lim JW 5

Affiliations 

  • 1 Department of Chemical and Environmental Engineering, Faculty of Science and Engineering, University of Nottingham Malaysia, Jalan Broga, Semenyih 43500, Selangor, Malaysia
  • 2 Department of Chemical and Environmental Engineering, Faculty of Science and Engineering, University of Nottingham Malaysia, Jalan Broga, Semenyih 43500, Selangor, Malaysia. Electronic address: Pauloke.show@nottingham.edu.my
  • 3 Institute of Engineering Thermophysics, Chongqing University, No. 174, Shazheng Str, Shapingba District, Chongqing 400032, China
  • 4 State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin, China
  • 5 Department of Fundamental and Applied Sciences, Universiti Teknologi Petronas, Persiaran UTP, Seri Iskandar, 32610 Perak, Malaysia
Bioresour Technol, 2019 Oct;289:121727.
PMID: 31279318 DOI: 10.1016/j.biortech.2019.121727

Abstract

In this present study, microalgal phycobiliproteins were isolated and purified via potential biphasic processing technique for pharmaceutical as well as food applications. The algal pre-treatment techniques were studied to enhance the yield of microalgal phycobiliproteins from the biomass. The proposed methods were optimised to obtain the best recovery yield of phycobiliproteins that can be isolated from the biomass. The phycobiliproteins were further purified using liquid biphasic system. The results showed that microalgal phycobiliproteins of high purity and yield was achieved using sonication treatment (20% power, 50% duty cycle and 7 min of irradiation time) with the biphasic system, where the purification fold of 6.17 and recovery yield of 94.89% was achieved. This work will provide insights towards the effective downstream processing of biomolecules from microalgae.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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