Affiliations 

  • 1 Centre for Biodiversity Conservation & Management, G.B. Pant National Institute of Himalayan Environment & Sustainable Development, Almora, India
  • 2 Department of Pharmaceutical Sciences, Faculty of Technology, Kumaun University Bhimtal Campus, Nainital, India
  • 3 Department of Pharmacognosy, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, India
  • 4 Department of Environmental Sciences, Faculty of Chemistry and Biology, Universidad de Santiago de Chile, Santiago, Chile
  • 5 Department of Pharmaceutical Botany, "Iuliu Hațieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania
  • 6 Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Division BIOCEV, Prague, Czechia
  • 7 Institute of Molecular Biology "Roumen Tsanev", Department of Biochemical Pharmacology and Drug Design, Bulgarian Academy of Sciences, Sofia, Bulgaria
  • 8 Department of Public Health, Xi'an Jiaotong-Liverpool University, Suzhou, China
  • 9 School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Malaysia
  • 10 Institute of Genetics and Animal Breeding of the Polish Academy of Sciences, Jastrzebiec, Poland
  • 11 Faculty of Chemistry, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego, Wrocław, Poland
Front Pharmacol, 2019;10:1593.
PMID: 32116660 DOI: 10.3389/fphar.2019.01593

Abstract

Excessive alcohol consumption is the cause of several diseases and thus is of a major concern for society. Worldwide alcohol consumption has increased by many folds over the past decades. This urgently calls for intervention and relapse counteract measures. Modern pharmacological solutions induce complete alcohol self-restraint and prevent relapse, but they have many side effects. Natural products are most promising as they cause fewer adverse effects. Here we discuss in detail the medicinal plants used in various traditional/folklore medicine systems for targeting alcohol abuse. We also comprehensively describe preclinical and clinical studies done on some of these plants along with the possible mechanisms of action.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.