Sexual dysfunction in polycystic ovary syndrome: a systematic review and meta-analysis

Loh HH 1 , Yee A 2 , Loh HS 3 , Kanagasundram S 4 , Francis B 4 , Lim LL 5

Affiliations 

  • 1 Faculty of Medicine and Health Sciences, Universiti Malaysia Sarawak, Jalan Datuk Muhammad Musa, 94300, Kota Samarahan, Sarawak, Malaysia. hhloh@unimas.my
  • 2 Department of Psychological Medicine, University Malaya Centre of Addiction Science (UMCAS), Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia. annyee17@um.edu.my
  • 3 Clinical Academic Unit, Newcastle University Medicine Malaysia, Iskandar Puteri, 79200, Johor, Malaysia
  • 4 Department of Psychological Medicine, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia
  • 5 Department of Medicine, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia
Hormones (Athens), 2020 Sep;19(3):413-423.
PMID: 32462512 DOI: 10.1007/s42000-020-00210-0

Abstract

PURPOSE: Polycystic ovarian syndrome (PCOS) is a common disorder characterized by clinical or biochemical hyperandrogenism and ovulary dysfunction. Female sexual dysfunction (FSD) adversely affects quality of life and interpersonal relationships. We aimed to compare the prevalence of FSD in women with and without PCOS.

METHODS: We pooled data from 28 observational studies involving 6256 women. Apart from the total prevalence of FSD, subgroup analyses based on different PCOS diagnostic criteria and obesity status (body mass index [BMI] ≥ 25 kg/m2) were performed. The differences in total and subscale scores of the Female Sexual Function Index (FSFI) among women with and without PCOS were also compared.

RESULTS: Women with PCOS were younger (mean ± SD 28.56 ± 3.0 vs 31.5 ± 3.2 years, p 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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