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Global Antimicrobial Stewardship with a Focus on Low- and Middle-Income Countries

Pierce J 1 , Apisarnthanarak A 2 , Schellack N 3 , Cornistein W 4 , Maani AA 5 , Adnan S 6 Show all authors , Stevens MP 7

Affiliations 

  • 1 Virginia Commonwealth University School of Medicine, Department of Internal Medicine, Division of Infectious Diseases, 1000 E Marshall St. Richmond, VA, USA, 23298. Electronic address: Jacob.Pierce@vcuhealth.org
  • 2 Thammasart University Hospital, 8 95 Phahonyothin Rd, Khlong Nueng, Khlong Luang District, Pathum Thani 12120
  • 3 Sefako-Makgatho Health Sciences University, School of Pharmacy, Pretoria. Motlegi St, Ga-Rankuwa Zone 1, Ga-Rankuwa, 0208, South Africa
  • 4 Hospital Universitario Austral Av. Juan Domingo Perón 1500, Pilar Centro, Buenos Aires, Argentina
  • 5 Directorate General for Disease Surveillance & Control, MOH. P.O Box: 393, PC 100 Muscat, Oman
  • 6 Hospital Sungai Buloh (Infectious Disease center) Jalan Hospital, 47000 Sungai Buloh, Selangor, Malaysia
  • 7 Virginia Commonwealth University School of Medicine, Department of Internal Medicine, Division of Infectious Diseases, 1000 E Marshall St. Richmond, VA, USA, 23298
Int J Infect Dis, 2020 Jul;96:621-629.
PMID: 32505875 DOI: 10.1016/j.ijid.2020.05.126

Abstract

Antimicrobial resistance is a global public health crisis. Antimicrobial Stewardship involves adopting systematic measures to optimize antimicrobial use, decrease unnecessary antimicrobial exposure and to decrease the emergence and spread of resistance. Low- and middle-income countries (LMICs) face a disproportionate burden of antimicrobial resistance and also face challenges related to resource availability. Although challenges exist, the World Health Organization has created a practical toolkit for developing Antimicrobial Stewardship Programs (ASPs) that will be summarized in this article.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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