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Diagnosis and potential treatments for acute hepatopancreatic necrosis disease (AHPND): a review

Santos HM 1 , Tsai CY 1 , Maquiling KRA 2 , Tayo LL 2 , Mariatulqabtiah AR 3 , Lee CW 4 Show all authors , Chuang KP 1

Affiliations 

  • 1 International Program in Animal Vaccine Technology, International College, National Pingtung University of Science and Technology, Neipu, 912 Pingtung Taiwan
  • 2 School of Chemical, Biological and Materials Engineering and Sciences, Mapúa University, 1002 Intramuros, Manila Philippines
  • 3 Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor Malaysia
  • 4 Department of Post-Baccalaureate Veterinary Medicine, Asia University, Taichung, 41354 Taiwan
Aquac Int, 2020;28(1):169-185.
PMID: 32834683 DOI: 10.1007/s10499-019-00451-w

Abstract

Acute hepatopancreatic necrosis disease (AHPND) or formerly known as early mortality syndrome (EMS) is an emerging disease that has caused significant economic losses to the aquaculture industry. The primary causative agent of AHPND is Vibrio parahaemolyticus, a Gram-negative rod-shaped bacterium that has gained plasmids encoding the fatal binary toxins Pir A/Pir B that cause rapid death of the infected shrimp. In this review, the current research studies and information about AHPND in shrimps have been presented. Molecular diagnostic tools and potential treatments regarding AHPND were also included. This review also includes relevant findings which may serve as guidelines that can help for further investigation and studies on AHPND or other shrimp diseases.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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