This paper aims to presents the implementation of Organizational Memory Information System (OMIS) framework in managing knowledge in organization. OMIS providing a way for organization to leveraging tacit knowledge in capturing, codifying, storing and transferring knowledge. Every year data, information and knowledge had increased then becomes wasted memories due to the retirement, replacement and resignation of staff. This can have a great impact if the knowledge is not used wisely for future purpose. This could give great impact when it is not used wisely. Organization become more efficient and competitive if they used the collections of memory in the form of collected data, information, and knowledge. Organizations which are not efficient will do the process, and study the same repeatedly. Implementation of this framework is a good way to increase effectiveness of knowledge sharing in university. But some knowledge is hard to capture especially tacit knowledge. Many organizations attempt to capture tacit knowledge and codify it so that it can be shared around the organization for greater value. So this paper is mainly focused on implementation of Organizational Memory Information System (OMIS) framework in order to manage knowledge more centralized and organized in organization.