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Can Kratom (Mitragyna speciosa) Alleviate COVID-19 Pain? A Case Study

Metastasio A 1 , Prevete E 2 , Singh D 3 , Grundmann O 4 , Prozialeck WC 5 , Veltri C 6 Show all authors , Bersani G 2 , Corazza O 1

Affiliations 

  • 1 School of Life and Medical Sciences, University of Hertfordshire, Hatfield, United Kingdom
  • 2 Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Rome, Italy
  • 3 Centre for Drug Research, Universiti Sains Malaysia, Minden, Malaysia
  • 4 Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL, United States
  • 5 Department of Pharmacology, Midwestern University, Downers Grove, IL, United States
  • 6 Department of Pharmaceutical Sciences, Midwestern University, Glendale, AZ, United States
Front Psychiatry, 2020;11:594816.
PMID: 33329145 DOI: 10.3389/fpsyt.2020.594816

Abstract

Among the symptoms of COVID-19 fever, general malaise, pain and aches, myalgia, fatigue, and headache can affect the quality of life of patients, even after the end of the acute phase of the infection and can be long lasting. The current treatment of these symptoms, also because COVID-19 patients have been asked not to use non-steroidal anti-inflammatory drugs (NSAIDs), in particular ibuprofen are often unsatisfactory. Among the above mentioned symptoms malaise and fatigue seem the most difficult to treat. In this case report we describe the use of kratom (Mitragyna speciosa) by a patient with confirmed COVID-19 infection. What we observed was a fast and sustained relieve of the above mentioned symptoms.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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