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Nanotechnology against the novel coronavirus (severe acute respiratory syndrome coronavirus 2): diagnosis, treatment, therapy and future perspectives

Rashidzadeh H 1 , Danafar H 2 , Rahimi H 2 , Mozafari F 2 , Salehiabar M 3 , Rahmati MA 2 Show all authors , Rahamooz-Haghighi S 4 , Mousazadeh N 2 , Mohammadi A 2 , Ertas YN 5 , Ramazani A 1 , Huseynova I 6 , Khalilov R 7 , Davaran S 7 , Webster TJ 8 , Kavetskyy T 7 , Eftekhari A 9 , Nosrati H 2 , Mirsaeidi M 10

Affiliations 

  • 1 Cancer Gene Therapy Research Center, Zanjan University of Medical Sciences, Zanjan, Iran
  • 2 Zanjan Pharmaceutical Biotechnology Research Center, Zanjan University of Medical Sciences, Zanjan, Iran
  • 3 Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz 51656-65811, Iran
  • 4 Department of Plant Production & Genetics, Faculty of Agriculture, University of Zanjan, Zanjan, Iran
  • 5 Department of Biomedical Engineering, Erciyes University, Kayseri 38039, Turkey
  • 6 Institute of Molecular Biology & Biotechnologies, Azerbaijan National Academy of Sciences, 11 Izzat Nabiyev, Baku AZ 1073, Azerbaijan
  • 7 Joint Ukraine-Azerbaijan International Research & Education Center of Nanobiotechnology & Functional Nanosystems, Drohobych, Ukraine, Baku, Azerbaijan
  • 8 Department of Chemical Engineering, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA
  • 9 Maragheh University of Medical Sciences, Maragheh 78151-55158, Iran
  • 10 Department of Public Health Sciences, University of Miami, Miami, FL 33146, USA
Nanomedicine (Lond), 2021 Mar;16(6):497-516.
PMID: 33683164 DOI: 10.2217/nnm-2020-0441

Abstract

COVID-19, as an emerging infectious disease, has caused significant mortality and morbidity along with socioeconomic impact. No effective treatment or vaccine has been approved yet for this pandemic disease. Cutting-edge tools, especially nanotechnology, should be strongly considered to tackle this virus. This review aims to propose several strategies to design and fabricate effective diagnostic and therapeutic agents against COVID-19 by the aid of nanotechnology. Polymeric, inorganic self-assembling materials and peptide-based nanoparticles are promising tools for battling COVID-19 as well as its rapid diagnosis. This review summarizes all of the exciting advances nanomaterials are making toward COVID-19 prevention, diagnosis and therapy.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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