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A literature review on beneficial role of vitamins and trace elements: Evidence from published clinical studies

Taheri S 1 , Asadi S 2 , Nilashi M 3 , Ali Abumalloh R 4 , Ghabban NMA 5 , Mohd Yusuf SY 6 Show all authors , Supriyanto E 7 , Samad S 8

Affiliations 

  • 1 Centre for Research in Biotechnology for Agriculture (CEBAR), University of Malaya, Kuala Lumpur, 50603, Malaysia
  • 2 Centre of Software Technology and Management, Faculty of Information Science and Technology, Universiti Kebangsaan Malaysia, Bangi, Selangor, 43600, Malaysia
  • 3 School of Biomedical Engineering and Health Sciences, Faculty of Engineering, Universiti Teknologi Malaysia, Skudai, Johor, 81310, Malaysia. Electronic address: nilashidotnet@hotmail.com
  • 4 Computer Department, Community College, Imam Abdulrahman Bin Faisal University, P.O. Box. 1982, Dammam, Saudi Arabia
  • 5 King Salman bin Abdulaziz Medical City, Madinah, Saudi Arabia
  • 6 Primary Care Medicine Department, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh, Selangor, 47000, Malaysia
  • 7 School of Biomedical Engineering and Health Sciences, Faculty of Engineering, Universiti Teknologi Malaysia, Skudai, Johor, 81310, Malaysia
  • 8 Department of Business Administration, College of Business and Administration, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia
J Trace Elem Med Biol, 2021 Sep;67:126789.
PMID: 34044222 DOI: 10.1016/j.jtemb.2021.126789

Abstract

COVID-19 is a kind of SARS-CoV-2 viral infectious pneumonia. This research aims to perform a bibliometric analysis of the published studies of vitamins and trace elements in the Scopus database with a special focus on COVID-19 disease. To achieve the goal of the study, network and density visualizations were used to introduce an overall picture of the published literature. Following the bibliometric analysis, we discuss the potential benefits of vitamins and trace elements on immune system function and COVID-19, supporting the discussion with evidence from published clinical studies. The previous studies show that D and A vitamins demonstrated a higher potential benefit, while Selenium, Copper, and Zinc were found to have favorable effects on immune modulation in viral respiratory infections among trace elements. The principles of nutrition from the findings of this research could be useful in preventing and treating COVID-19.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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