Cost analysis of utilising wound edge protector in open appendicectomy to prevent surgical site infection

Muniandy J 1 , Azman A 2 , Murugasan V 1 , Alwi RI 1 , Zuhdi Z 2 , Jarmin R 2 Show all authors , Osman S 3

Affiliations 

  • 1 Department of Surgery, Sultanah Aminah General Hospital, Johor Bahru, Johor, Malaysia
  • 2 Department of Surgery, University Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia
  • 3 Ministry of Health, Malaysia
Ann Med Surg (Lond), 2021 Aug;68:102573.
PMID: 34354831 DOI: 10.1016/j.amsu.2021.102573

Abstract

Background: The rate of surgical site infection (SSI) differ with variable nature with appendicitis with a global incidence of up to 11%. Several randomised trials describe a significant reduction in incisional SSI using wound edge protectors (WEP), mainly in elective procedures. This study was designed to analyse WEP use in emergency open appendicectomy.

Method: This randomised controlled trial enrolled 200 patients who underwent emergency open appendicectomy. Permuted block randomisation was used to assign subjects to either mechanical retraction or double ring WEP. The primary endpoints were SSI rates and cost analysis between the methods.

Results: The incidence of SSI was similar, n = 7 (7.4%) in the control group and n = 8 (8.4%) in the WEP group, and demonstrates no statistically significant difference (p > 0.05). Cost analysis showed a statistically significant (p 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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