Displaying publications 1 - 20 of 28 in total

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  1. Abd Aziz M, Hamzaid NA, Hasnan N
    J Vis Exp, 2022 Nov 11.
    PMID: 36440840 DOI: 10.3791/63149
    Execution of Sit-to-Stand (SitTS) in incomplete spinal cord injury (SCI) patients involves motor function in both upper and lower extremities. The use of arm support, in particular, is a significant assistive factor while executing SitTS movement in SCI population. In addition, the application of functional electrical stimulation (FES) onto quadriceps and gluteus maximus muscles is one of the prescribed management for incomplete SCI to improve muscle action for simple lower limb movements. However, the relative contribution of upper and lower extremities during SitTS has not been thoroughly investigated. Two motor incomplete SCI paraplegics performed repetitive SitTS to fatigue exercise challenge. Their performance was investigated as a mixed-method case-control study comparing SitTS with and without the assistance of FES. Three sets of SitTS tests were completed with 5-min resting period allocated in between sets, with mechanomyography (MMG) sensors attached over the rectus femoris muscles bilaterally. The exercise was separated into 2 sessions; Day 1 for voluntary SitTS and Day 2 for FES-assisted SitTS. Questionnaires were conducted after every session to gather the participants' input about their repetitive SitTS experience. The analysis confirmed that a SitTS cycle could be divided into three phases; Phase 1 (Preparation to stand), Phase 2 (Seat-off), and Phase 3 (Initiation of hip extension), which contributed to 23% ± 7%, 16% ± 4% and 61% ± 6% of the SitTS cycle, respectively. The contribution of arms and legs during SitTS movement varied in different participants based on their legs' Medical Research Council (MRC) muscle grade. In particular, the applied arm forces start to increase clearly when the leg forces start to decline during standing. This finding is supported by the significantly reduced MMG signal indicating leg muscle fatigue and their reported feeling of tiredness.
    Matched MeSH terms: Muscle Fatigue/physiology
  2. Abdullah, S., Putra, T.E., Nuawi, M.Z., Nopiah, Z.M.
    MyJurnal
    This paper presents a new approach to identify fatigue damaging potential locations using the Morlet wavelet coefficients. For solving the subject matter, the 122.4 second SAESUS strain signal was selected for the simulation purpose. As the result, the Morlet wavelet coefficients predicted that the maximum fatigue damage occurs at 40.4 - 42.6 seconds and 67.4 - 70 seconds. For the validation purpose, the Morrow’s fatigue damaging value was calculated and was obtained that the maximum fatigue damage occurs at 0 seconds and 99.7 seconds. The fatigue damaging value at the points was 0.0047 cycles to failure. Since both the plots had similar pattern, the Morlet wavelet coefficients could be used as the early warning of the fatigue damaging potential locations, although the locations were not entirely correct.
    Matched MeSH terms: Muscle Fatigue
  3. Ajit Singh DK, Bailey M, Lee R
    Muscle Nerve, 2011 Jul;44(1):74-9.
    PMID: 21488056 DOI: 10.1002/mus.21998
    Loss of lumbar extensor muscle strength and fatigue resistance may contribute to functional disability.
    Matched MeSH terms: Muscle Fatigue/physiology*
  4. Ali A, Sundaraj K, Badlishah Ahmad R, Ahamed NU, Islam A, Sundaraj S
    J Hum Kinet, 2015 Jun 27;46:69-76.
    PMID: 26240650 DOI: 10.1515/hukin-2015-0035
    The objective of the present study was to investigate the time to fatigue and compare the fatiguing condition among the three heads of the triceps brachii muscle using surface electromyography during an isometric contraction of a controlled forceful hand grip task with full elbow extension. Eighteen healthy subjects concurrently performed a single 90 s isometric contraction of a controlled forceful hand grip task and full elbow extension. Surface electromyographic signals from the lateral, long and medial heads of the triceps brachii muscle were recorded during the task for each subject. The changes in muscle activity among the three heads of triceps brachii were measured by the root mean square values for every 5 s period throughout the total contraction period. The root mean square values were then analysed to determine the fatiguing condition for the heads of triceps brachii muscle. Muscle fatigue in the long, lateral, and medial heads of the triceps brachii started at 40 s, 50 s, and 65 s during the prolonged contraction, respectively. The highest fatiguing rate was observed in the long head (slope = -2.863), followed by the medial head (slope = -2.412) and the lateral head (slope = -1.877) of the triceps brachii muscle. The results of the present study concurs with previous findings that the three heads of the triceps brachii muscle do not work as a single unit, and the fiber type/composition is different among the three heads.
    Matched MeSH terms: Muscle Fatigue
  5. Amir Bahram Kashiani, Kim, Geok Soh, Kim, Lam Soh, Swee, Leong Ong, Kittichottipanich, Boonsrin
    Movement Health & Exercise, 2020;9(1):45-66.
    MyJurnal
    Several studies have shown a positive association between variable resistance training (VRT) and improvements in muscular performance. However, the effects of VRT on body composition among untrained individuals remain unclear. The objective of this study was to examine the comparison between of methods of VRT on body composition, muscular strength and functional capacity among untrained male adults. Fifty healthy untrained males (age: 21.5 ± 1.95 years) were selected randomly and assigned into three groups: combined weight and chain (WC), combined weight and elastic band (WE), and free-weight (CG). All three groups completed 12 weeks of high intensity resistance training (70-80% of one-repetition maximum) with three sets of 8-12 repetitions two times per week. Approximately 65% of the whole resistance was provided by free-weights, while the other 35% of the resistance was provided by chains and elastic bands for the WC and WE groups, respectively. Dependent variables including body composition, muscular strength and functional capacity using bioelectrical impedance analyzer, one-repetition maximum and maximum repetitions to muscular fatigue were measured, respectively in pre-test, post-test 1 (week 6) and post-test 2. Significance level was set at P < 0.05. No differences existed among all groups at baseline for depended variables. A mixed model ANOVA with repeated measurements analysis revealed that although there were not significant differences in body composition among the groups (P > 0.05), all groups showed a significant reduction in fat mass and significant increase in fat-free mass during and after the intervention (P = 0.0001), and these differences were insignificantly greater in WE and WC groups compared with CG group. Furthermore, all three groups showed significant improvements in muscular strength and functional capacity during and after intervention (P = 0.0001), and muscular strength and functional capacity were greater in WE and WC groups compared with the CG group, but there were not significant differences in muscular strength and functional capacity between WE and WC groups. However, the WE group showed insignificantly more improvement in muscular strength and functional capacity compared with the WC group during and after the intervention. The results of this study show that VRT has a slightly better effect than free-weight to improve body composition during and after 12 weeks intervention. Also, WE training had a slightly better effect than WC training in improving muscular strength and functional capacity during and after 12 weeks of VRT among untrained male adults.
    Matched MeSH terms: Muscle Fatigue
  6. Ayuni Nabilah Alias, Karmegam Karuppiah, Vivien How, Velu Perumal
    MyJurnal
    In order to accomplish a wide range of duties and responsibilities that may be done under unpleasant working con- ditions, prolonged standing posture is common with school teachers. Nevertheless, standing upright for a long time or otherwise regarded as prolonged standing frequently contributes to body pain and discomfort, muscle fatigue and even health problems such as musculoskeletal disorders (MSDs). The aim of this paper is to review MSDs arising from prolonged standing and spread information on existing ergonomic and non-ergonomic interventions to alleviate prolonged standing discomfort. Systematic review on prolonged standing school teachers with specific keywords were recognized to discover the appropriate studies and information in a systematic search. The informations in this review may be helpful to guide teacher, school management and researchers to implement the suitable interventions in order to minimise the health issue due to MSDs among school teachers.
    Matched MeSH terms: Muscle Fatigue
  7. Glazier PS
    Hum Mov Sci, 2017 Dec;56(Pt A):139-156.
    PMID: 26725372 DOI: 10.1016/j.humov.2015.08.001
    Sports performance is generally considered to be governed by a range of interacting physiological, biomechanical, and psychological variables, amongst others. Despite sports performance being multi-factorial, however, the majority of performance-oriented sports science research has predominantly been monodisciplinary in nature, presumably due, at least in part, to the lack of a unifying theoretical framework required to integrate the various subdisciplines of sports science. In this target article, I propose a Grand Unified Theory (GUT) of sports performance-and, by elaboration, sports science-based around the constraints framework introduced originally by Newell (1986). A central tenet of this GUT is that, at both the intra- and inter-individual levels of analysis, patterns of coordination and control, which directly determine the performance outcome, emerge from the confluence of interacting organismic, environmental, and task constraints via the formation and self-organisation of coordinative structures. It is suggested that this GUT could be used to: foster interdisciplinary research collaborations; break down the silos that have developed in sports science and restore greater disciplinary balance to the field; promote a more holistic understanding of sports performance across all levels of analysis; increase explanatory power of applied research work; provide stronger rationale for data collection and variable selection; and direct the development of integrated performance monitoring technologies. This GUT could also provide a scientifically rigorous basis for integrating the subdisciplines of sports science in applied sports science support programmes adopted by high-performance agencies and national governing bodies for various individual and team sports.
    Matched MeSH terms: Muscle Fatigue/physiology
  8. Halim I, Arep H, Kamat SR, Abdullah R, Omar AR, Ismail AR
    Saf Health Work, 2014 Jun;5(2):97-105.
    PMID: 25180141 DOI: 10.1016/j.shaw.2014.04.002
    BACKGROUND: Prolonged standing has been hypothesized as a vital contributor to discomfort and muscle fatigue in the workplace. The objective of this study was to develop a decision support system that could provide systematic analysis and solutions to minimize the discomfort and muscle fatigue associated with prolonged standing.

    METHODS: The integration of object-oriented programming and a Model Oriented Simultaneous Engineering System were used to design the architecture of the decision support system.

    RESULTS: Validation of the decision support system was carried out in two manufacturing companies. The validation process showed that the decision support system produced reliable results.

    CONCLUSION: The decision support system is a reliable advisory tool for providing analysis and solutions to problems related to the discomfort and muscle fatigue associated with prolonged standing. Further testing of the decision support system is suggested before it is used commercially.

    Matched MeSH terms: Muscle Fatigue
  9. Hussain J, Sundaraj K, Subramaniam ID, Lam CK
    J Musculoskelet Neuronal Interact, 2019 09 01;19(3):276-285.
    PMID: 31475934
    OBJECTIVE: The objective of this study was to investigate fatigue in the three heads of the triceps brachii (TB) muscle using surface electromyography (sEMG) obtained at 30%, 45% and 60% of maximal voluntary contraction (MVC).

    METHODS: Twenty-five subjects performed isometric elbow extension until failure, and the rate of fatigue (ROF), time to fatigue (TTF) and normalized TTF (NTTF) were statistically analysed. Subsequently, the behaviour of root-mean-square (RMS), mean-power frequency (MPF) and median-power frequency (MDF) under pre-, onset- and post-fatigue conditions were compared.

    RESULTS: The findings indicated that, among the heads, ROF was statistically significant at 30% and 45% MVC (P<0.05) but TTF and NTTF at all intensities was statistically insignificant (P>0.05). For every head, only TTF was statistically significant (P<0.05) at different intensities. MPF and MDF under pre-, onset- and post-fatigue conditions were statistically significant (P<0.05) among the heads at all intensities, whereas RMS showed no such behaviour.

    CONCLUSION: The investigated parameters reveal that the three heads of TB act independently before fatigue onset and appear to work in union after fatigue. Synergist head pairs exhibit similar spectral and temporal behaviour in contrast to the non-synergist TB head pair. We find spectral parameters to be more specific predictors of fatigue.

    Matched MeSH terms: Muscle Fatigue/physiology*
  10. Hussain J, Sundaraj K, Subramaniam ID
    PLoS One, 2020;15(1):e0228089.
    PMID: 31999750 DOI: 10.1371/journal.pone.0228089
    INTRODUCTION: Cognitive stress (CS) changes the peripheral attributes of a muscle, but its effect on multi-head muscles has not been investigated. The objective of the current research was to investigate the impact of CS on the three heads of the triceps brachii (TB) muscle.

    METHODS: Twenty-five young and healthy university students performed a triceps push-down exercise at 45% one repetition maximum (1RM) with and without CS until task failure, and the rate of fatigue (ROF), endurance time (ET) and number of repetitions (NR) for both exercises were analyzed. In addition, the first and last six repetitions of each exercise were considered non-fatiguing (NF) and fatiguing (Fa), respectively, and the root mean square (RMS), mean power frequency (MPF) and median frequency (MDF) for each exercise repetition were evaluated.

    RESULTS: The lateral and long head showed significant differences (P<0.05) in the ROF between the two exercises, and all the heads showed significant (P<0.05) differences in the RMS between the two exercises under NF conditions. Only the long head showed a significant difference (P<0.05) in the MPF and MDF between the two exercises. CS increases the ET (24.74%) and NR (27%) of the exercise. The three heads showed significant differences (P<0.05) in the RMS, MPF and MDF under all exercise conditions.

    CONCLUSION: A lower ROF was obtained with CS. In addition, the RMS was found to be better approximator of CS, whereas MPF and MDF were more resistant to the effect of CS. The results showed that the three heads worked independently under all conditions, and the non-synergist and synergist head pairs showed similar behavior under Fa conditions. The findings from this study provide additional insights regarding the functioning of each TB head.

    Matched MeSH terms: Muscle Fatigue/physiology*
  11. Ibitoye MO, Estigoni EH, Hamzaid NA, Wahab AK, Davis GM
    Sensors (Basel), 2014;14(7):12598-622.
    PMID: 25025551 DOI: 10.3390/s140712598
    The evoked electromyographic signal (eEMG) potential is the standard index used to monitor both electrical changes within the motor unit during muscular activity and the electrical patterns during evoked contraction. However, technical and physiological limitations often preclude the acquisition and analysis of the signal especially during functional electrical stimulation (FES)-evoked contractions. Hence, an accurate quantification of the relationship between the eEMG potential and FES-evoked muscle response remains elusive and continues to attract the attention of researchers due to its potential application in the fields of biomechanics, muscle physiology, and rehabilitation science. We conducted a systematic review to examine the effectiveness of eEMG potentials to assess muscle force and fatigue, particularly as a biofeedback descriptor of FES-evoked contractions in individuals with spinal cord injury. At the outset, 2867 citations were identified and, finally, fifty-nine trials met the inclusion criteria. Four hypotheses were proposed and evaluated to inform this review. The results showed that eEMG is effective at quantifying muscle force and fatigue during isometric contraction, but may not be effective during dynamic contractions including cycling and stepping. Positive correlation of up to r = 0.90 (p < 0.05) between the decline in the peak-to-peak amplitude of the eEMG and the decline in the force output during fatiguing isometric contractions has been reported. In the available prediction models, the performance index of the eEMG signal to estimate the generated muscle force ranged from 3.8% to 34% for 18 s to 70 s ahead of the actual muscle force generation. The strength and inherent limitations of the eEMG signal to assess muscle force and fatigue were evident from our findings with implications in clinical management of spinal cord injury (SCI) population.
    Matched MeSH terms: Muscle Fatigue*
  12. Ibitoye MO, Hamzaid NA, Hasnan N, Abdul Wahab AK, Davis GM
    PLoS One, 2016;11(2):e0149024.
    PMID: 26859296 DOI: 10.1371/journal.pone.0149024
    BACKGROUND: Rapid muscle fatigue during functional electrical stimulation (FES)-evoked muscle contractions in individuals with spinal cord injury (SCI) is a significant limitation to attaining health benefits of FES-exercise. Delaying the onset of muscle fatigue is often cited as an important goal linked to FES clinical efficacy. Although the basic concept of fatigue-resistance has a long history, recent advances in biomedical engineering, physiotherapy and clinical exercise science have achieved improved clinical benefits, especially for reducing muscle fatigue during FES-exercise. This review evaluated the methodological quality of strategies underlying muscle fatigue-resistance that have been used to optimize FES therapeutic approaches. The review also sought to synthesize the effectiveness of these strategies for persons with SCI in order to establish their functional impacts and clinical relevance.

    METHODS: Published scientific literature pertaining to the reduction of FES-induced muscle fatigue was identified through searches of the following databases: Science Direct, Medline, IEEE Xplore, SpringerLink, PubMed and Nature, from the earliest returned record until June 2015. Titles and abstracts were screened to obtain 35 studies that met the inclusion criteria for this systematic review.

    RESULTS: Following the evaluation of methodological quality (mean (SD), 50 (6) %) of the reviewed studies using the Downs and Black scale, the largest treatment effects reported to reduce muscle fatigue mainly investigated isometric contractions of limited functional and clinical relevance (n = 28). Some investigations (n = 13) lacked randomisation, while others were characterised by small sample sizes with low statistical power. Nevertheless, the clinical significance of emerging trends to improve fatigue-resistance during FES included (i) optimizing electrode positioning, (ii) fine-tuning of stimulation patterns and other FES parameters, (iii) adjustments to the mode and frequency of exercise training, and (iv) biofeedback-assisted FES-exercise to promote selective recruitment of fatigue-resistant motor units.

    CONCLUSION: Although the need for further in-depth clinical trials (especially RCTs) was clearly warranted to establish external validity of outcomes, current evidence was sufficient to support the validity of certain techniques for rapid fatigue-reduction in order to promote FES therapy as an integral part of SCI rehabilitation. It is anticipated that this information will be valuable to clinicians and other allied health professionals administering FES as a treatment option in rehabilitation and aid the development of effective rehabilitation interventions.

    Matched MeSH terms: Muscle Fatigue/physiology*
  13. Islam MA, Sundaraj K, Ahmad RB, Ahamed NU
    PLoS One, 2013;8(3):e58902.
    PMID: 23536834 DOI: 10.1371/journal.pone.0058902
    BACKGROUND: Mechanomyography (MMG) has been extensively applied in clinical and experimental practice to examine muscle characteristics including muscle function (MF), prosthesis and/or switch control, signal processing, physiological exercise, and medical rehabilitation. Despite several existing MMG studies of MF, there has not yet been a review of these. This study aimed to determine the current status on the use of MMG in measuring the conditions of MFs.

    METHODOLOGY/PRINCIPAL FINDINGS: Five electronic databases were extensively searched for potentially eligible studies published between 2003 and 2012. Two authors independently assessed selected articles using an MS-Word based form created for this review. Several domains (name of muscle, study type, sensor type, subject's types, muscle contraction, measured parameters, frequency range, hardware and software, signal processing and statistical analysis, results, applications, authors' conclusions and recommendations for future work) were extracted for further analysis. From a total of 2184 citations 119 were selected for full-text evaluation and 36 studies of MFs were identified. The systematic results find sufficient evidence that MMG may be used for assessing muscle fatigue, strength, and balance. This review also provides reason to believe that MMG may be used to examine muscle actions during movements and for monitoring muscle activities under various types of exercise paradigms.

    CONCLUSIONS/SIGNIFICANCE: Overall judging from the increasing number of articles in recent years, this review reports sufficient evidence that MMG is increasingly being used in different aspects of MF. Thus, MMG may be applied as a useful tool to examine diverse conditions of muscle activity. However, the existing studies which examined MMG for MFs were confined to a small sample size of healthy population. Therefore, future work is needed to investigate MMG, in examining MFs between a sufficient number of healthy subjects and neuromuscular patients.

    Matched MeSH terms: Muscle Fatigue/physiology
  14. Jamaluddin FN, Ibrahim F, Ahmad SA
    J Healthc Eng, 2023;2023:1951165.
    PMID: 36756137 DOI: 10.1155/2023/1951165
    In sports, fatigue management is vital as adequate rest builds strength and enhances performance, whereas inadequate rest exposes the body to prolonged fatigue (PF) or also known as overtraining. This paper presents PF identification and classification based on surface electromyography (EMG) signals. An experiment was performed on twenty participants to investigate the behaviour of surface EMG during the inception of PF. PF symptoms were induced in accord with a five-day Bruce Protocol treadmill test on four lower extremity muscles: the biceps femoris (BF), rectus femoris (RF), vastus medialis (VM), and vastus lateralis (VL). The results demonstrate that the experiment successfully induces soreness, unexplained lethargy, and performance decrement and also indicate that the progression of PF can be observed based on changes in frequency features (ΔF med and ΔF mean) and time features (ΔRMS and ΔMAV) of surface EMG. This study also demonstrates the ability of wavelet index features in PF identification. Using a naïve Bayes (NB) classifier exhibits the highest accuracy based on time and frequency features with 98% in distinguishing PF on RF, 94% on BF, 9% on VL, and 97% on VM. Thus, this study has positively indicated that surface EMG can be used in identifying the inception of PF. The implication of the findings is significant in sports to prevent a greater risk of PF.
    Matched MeSH terms: Muscle Fatigue*
  15. Khong TK, Selvanayagam V, Yusof A
    Eur J Sport Sci, 2021 Feb;21(2):224-230.
    PMID: 32056510 DOI: 10.1080/17461391.2020.1730980
    Carbohydrate (CHO) mouth rinse has been shown to improve endurance performance and maintain the central drive of contracting muscles. Salt (NaCl) mouth rinse solution, often used in dentistry to desensitise the oral cavity to pain, could also activate cortical areas of the brain. Hence, the objective of this preliminary study was to investigate whether CHO (glucose) and NaCl mouth rinses could attenuate the reduction in maximum voluntary contraction (MVC) and sustained MVC (sMVC) following an endurance exercise (30-minute cycling at 70% VO2max). Ten subjects (male, age: 22 ± 1 years, weight: 65.3 ± 12.4 kg, height: 164.5 ± 7.5 cm, VO2max: 48.3 ± 6.1 mL kg-1 min-1) completed three trials of 30-minute cycling exercise. In a randomised cross-over study, in each trial, the participants rinsed using either water, 6% glucose, or 6% NaCl solution for 5 s immediately prior to and every 10 min during the cycling exercise. The MVC and sMVC were measured pre and post cycling. Analysis of variance showed significant interaction and time effects for MVC, while for sMVC there was a significant interaction with time and group effects. Both MVC and sMVC were higher post cycling in the glucose and NaCl groups compared to the water group, which suggests that activation of glucose and NaCl oral receptors could better preserve post-exercise force production. This is the first study to show that NaCl mouth rinse can produce a comparable effect on glucose. Hence, mouth rinses may be able to activate other distinct pathways that could attenuate fatigue.
    Matched MeSH terms: Muscle Fatigue/drug effects*
  16. Khong TK, Selvanayagam VS, Sidhu SK, Yusof A
    Scand J Med Sci Sports, 2017 Apr;27(4):376-384.
    PMID: 27714855 DOI: 10.1111/sms.12754
    Carbohydrate (CHO) depletion is linked to neuromuscular fatigue during exercise. While its role at peripheral level is relatively well understood, less is known about its impact centrally. The aim of this systematic review was to critically analyze the effects of CHO on central fatigue (CF) assessed by various neurophysiological techniques. Four databases were searched using PRISMA guidelines through February 2016. The inclusion criteria were: CHO as intervention against a placebo control, fatigue induced by prolonged exercise and assessed using neurophysiological measures [voluntary activation (VA), superimposed twitch (SIT), M-wave, electromyography], alongside maximal voluntary contraction (MVC). Seven papers were reviewed, where exercise duration lasted between 115 and 180 min. CHO improved exercise performance in three studies, whereby two of them attributed it to CF via attenuation of VA and SIT reductions, while the other indicated peripheral involvement via attenuation of M-wave reduction. Although a few studies suggest that CHO attenuates CF, data on its direct effects on neurophysiological outcome measures are limited and mixed. Generally, measures employed in these studies were inadequate to conclude central contribution to fatigue. Factors including the techniques used and the lack of controls render additional confounding factors to make definitive deductions. Future studies should employ consistent techniques and appropriate neurophysiological controls to distinguish CHO effect at central level. The use of pharmacological intervention should be incorporated to elucidate involvement of central mechanisms.
    Matched MeSH terms: Muscle Fatigue
  17. Manaf FA, Peiffer JJ, Maker GL, Fairchild TJ
    J Sci Med Sport, 2021 Apr;24(4):412-417.
    PMID: 33162329 DOI: 10.1016/j.jsams.2020.10.014
    OBJECTIVES: To investigate the effects of acute branched-chain amino acid (BCAA) supplementation on cycling performance and neuromuscular fatigue during a prolonged, self-paced cycling time-trial.

    DESIGN: Randomised double-blind counterbalanced crossover.

    METHODS: Eighteen recreationally active men (mean±SD; age: 24.7±4.8 years old; body-weight, BW: 67.1±6.1kg; height: 171.7±4.9cm) performed a cycling time-trial on an electromagnetically-braked cycle ergometer. Participants were instructed to complete the individualised total work in the shortest time possible, while ingesting either BCAAs (pre-exercise: 0.084gkg-1 BW; during exercise: 0.056gkg-1h-1) or a non-caloric placebo solution. Rating of perceived exertion, power, cadence and heart rate were recorded throughout, while maximal voluntary contraction, muscle voluntary activation level and electrically evoked torque using single and doublet stimulations were assessed at baseline, immediately post-exercise and 20-min post-exercise.

    RESULTS: Supplementation with BCAA reduced (287.9±549.7s; p=0.04) time-to-completion and ratings of perceived exertion (p≤0.01), while concomitantly increasing heart rate (p=0.02). There were no between-group differences (BCAA vs placebo) in any of the neuromuscular parameters, but significant decreases (All p≤0.01) in maximal voluntary contraction, muscle voluntary activation level and electrically evoked torque (single and doublet stimulations) were recorded immediately following the trial, and these did not recover to pre-exercise values by the 20min recovery time-point.

    CONCLUSIONS: Compared to a non-caloric placebo, acute BCAA supplementation significantly improved performance in cycling time-trial among recreationally active individuals without any notable changes in either central or peripheral factors. This improved performance with acute BCAA supplementation was associated with a reduced rating of perceived exertion.

    Matched MeSH terms: Muscle Fatigue/drug effects*
  18. Mohamad Ismail MR, Lam CK, Sundaraj K, Rahiman MHF
    J Musculoskelet Neuronal Interact, 2021 12 01;21(4):481-494.
    PMID: 34854387
    OBJECTIVE: This paper presents the analyses of the fatigue effect on the cross-talk in mechanomyography (MMG) signals of extensor and flexor forearm muscles during pre- and post-fatigue maximum voluntary isometric contraction (MVIC).

    METHODS: Twenty male participants performed repetitive submaximal (60% MVIC) grip muscle contractions to induce muscle fatigue and the results were analyzed during the pre- and post-fatigue MVIC. MMG signals were recorded on the extensor digitorum (ED), extensor carpi radialis longus (ECRL), flexor digitorum superficialis (FDS) and flexor carpi radialis (FCR) muscles. The cross-correlation coefficient was used to quantify the cross-talk values in forearm muscle pairs (MP1, MP2, MP3, MP4, MP5 and MP6). In addition, the MMG RMS and MMG MPF were calculated to determine force production and muscle fatigue level, respectively.

    RESULTS: The fatigue effect significantly increased the cross-talk values in forearm muscle pairs except for MP2 and MP6. While the MMG RMS and MMG MPF significantly decreased (p<0.05) based on the examination of the mean differences from pre- and post-fatigue MVIC.

    CONCLUSION: The presented results can be used as a reference for further investigation of cross-talk on the fatigue assessment of extensor and flexor muscles' mechanic.

    Matched MeSH terms: Muscle Fatigue
  19. Mohamad NZ, Hamzaid NA, Davis GM, Abdul Wahab AK, Hasnan N
    Sensors (Basel), 2017 Jul 14;17(7).
    PMID: 28708068 DOI: 10.3390/s17071627
    A mechanomyography muscle contraction (MC) sensor, affixed to the skin surface, was used to quantify muscle tension during repetitive functional electrical stimulation (FES)-evoked isometric rectus femoris contractions to fatigue in individuals with spinal cord injury (SCI). Nine persons with motor complete SCI were seated on a commercial muscle dynamometer that quantified peak torque and average torque outputs, while measurements from the MC sensor were simultaneously recorded. MC-sensor-predicted measures of dynamometer torques, including the signal peak (SP) and signal average (SA), were highly associated with isometric knee extension peak torque (SP: r = 0.91, p < 0.0001), and average torque (SA: r = 0.89, p < 0.0001), respectively. Bland-Altman (BA) analyses with Lin's concordance (ρC) revealed good association between MC-sensor-predicted peak muscle torques (SP; ρC = 0.91) and average muscle torques (SA; ρC = 0.89) with the equivalent dynamometer measures, over a range of FES current amplitudes. The relationship of dynamometer torques and predicted MC torques during repetitive FES-evoked muscle contraction to fatigue were moderately associated (SP: r = 0.80, p < 0.0001; SA: r = 0.77; p < 0.0001), with BA associations between the two devices fair-moderate (SP; ρC = 0.70: SA; ρC = 0.30). These findings demonstrated that a skin-surface muscle mechanomyography sensor was an accurate proxy for electrically-evoked muscle contraction torques when directly measured during isometric dynamometry in individuals with SCI. The novel application of the MC sensor during FES-evoked muscle contractions suggested its possible application for real-world tasks (e.g., prolonged sit-to-stand, stepping,) where muscle forces during fatiguing activities cannot be directly measured.
    Matched MeSH terms: Muscle Fatigue
  20. Mohd Safee MK, Abu Osman NA
    Occup Ther Int, 2021;2021:4357473.
    PMID: 34707468 DOI: 10.1155/2021/4357473
    Muscle fatigue is a decline in muscle maximum force during contraction and can influence the fall risk among people. This study is aimed at identifying the effect of fatigue on prospective fall risk in transfemoral amputees (TFA). Fourteen subjects were involved in this study with TFA (34.7 ± 8.1 yrs, n = 7) and normal subjects (31.1 ± 7.4 yrs, n = 7). Fatigue of lower limb muscles was induced with the fatigue protocol. Subjects were tested prefatigue and postfatigue using the standardized fall risk assessment. All results were calculated and compared between pre- and postfatigue to identify fatigue's effect on both groups of subjects. The results showed that the fall risk increased significantly during pre- and postfatigue for TFA (p = 0.018), while there were no significant differences in normal subjects (p = 0.149). Meanwhile, the fall risk between TFA and normal subjects for prefatigue (p = 0.082) and postfatigue (p = 0.084) also showed no significant differences. The percentage (%) of increased fall risk for TFA was 19.2% compared to normal subjects only 16.7%. However, 61.4% increased of % fall risk in TFA after fatigue by using the baseline of the normal subject as the normalized % of fall risk. The increasing fall risks for TFA after fatigue are three times higher than the potential fall risk in normal subjects. The result indicates that they need to perform more precautions while prolonging lower limb activities. These results showed the implications of fatigue that can increase the fall risk due to muscle fatigue from repetitive and prolonged activities. Therefore, rehabilitation programs can be done very safely and precisely so that therapists can pursue fitness without aggravating existing injuries.
    Matched MeSH terms: Muscle Fatigue
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